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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vetpress</journal-id><journal-title-group><journal-title xml:lang="ru">Аграрная наука</journal-title><trans-title-group xml:lang="en"><trans-title>Agrarian science</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-8155</issn><issn pub-type="epub">2686-701X</issn><publisher><publisher-name>Редакция журнала "Аграрная наука"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.32634/0869-8155-2021-348-4-35-43</article-id><article-id custom-type="elpub" pub-id-type="custom">vetpress-1630</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОРМОПРОИЗВОДСТВО, КОРМЛЕНИЕ С/Х ЖИВОТНЫХ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FORAGE PRODUCTION, FEEDING OF AGRICULTURAL ANIMALS</subject></subj-group></article-categories><title-group><article-title>Полиферментные препараты в кормлении моногастричных животных</article-title><trans-title-group xml:lang="en"><trans-title>Polyenzyme preparations in feeding of monogastric animals</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крюков</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kryukov</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><bio xml:lang="en"><p>Moscow </p></bio><email xlink:type="simple">kryukov.v.s@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зиновьев</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zinoviev</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>п. Ржавки Московской обл.</p></bio><bio xml:lang="en"><p>Rzhavki village, Moscow region </p></bio><email xlink:type="simple">neollit_13@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Некрасов</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Nekrasov</surname><given-names>R. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Подольск пос., Дубровицы</p></bio><bio xml:lang="en"><p>Podolsk, Dubrovitsy, Moscow Region </p></bio><email xlink:type="simple">nek_roman@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глебова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Glebova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Курск</p></bio><bio xml:lang="en"><p> Kursk</p></bio><email xlink:type="simple">snow1968@inbox.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галецкий</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Galetsky</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ленинградская обл., Гатчинский р-н, д. Малые Колпаны</p></bio><bio xml:lang="en"><p>Leningrad region. Gatchinsky district, Malye Kolpany village </p></bio><email xlink:type="simple">vl.galetski@gmail.com</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ООО «Кормогран»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kormogran LLC</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution> ВНИИПП – филиал ФНЦ ВНИТИП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>VNIIPP — branch of the VNITIP Federal Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБНУ ФИЦ ВИЖ им. Л.К. Эрнста</institution><country>Россия</country></aff><aff xml:lang="en"><institution>L.K. Ernst Federal Research Center for Animal Husbandry</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Курская ГСХА</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kursk State Agricultural Academy</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Гатчинский ККЗ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Gatchina KKZ</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>18</day><month>06</month><year>2021</year></pub-date><volume>0</volume><issue>4</issue><fpage>35</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Крюков В.С., Зиновьев С.В., Некрасов Р.В., Глебова И.В., Галецкий В.Б., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Крюков В.С., Зиновьев С.В., Некрасов Р.В., Глебова И.В., Галецкий В.Б.</copyright-holder><copyright-holder xml:lang="en">Kryukov V.S., Zinoviev S.V., Nekrasov R.V., Glebova I.V., Galetsky V.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vetpress.ru/jour/article/view/1630">https://www.vetpress.ru/jour/article/view/1630</self-uri><abstract><p> Для кормовых целей в основном используют ферментные препараты, которые содержат ферменты, не  вырабатываемые в организме животных, хотя у цыплят  первых недель жизни и поросят после отъема образуется  недостаточное количество собственных протеаз и амилаз, поэтому их включение в корма тоже оказывается полезным. К настоящему времени созданы и производятся  высокоактивные ферментные препараты, обладающие  различными специфическими активностями. В кормах, приготовленных с использованием традиционного сырья,  до 30% питательных веществ недоступны для  переваривания ферментами, секретируемыми в ЖКТ. Включение в корма экзогенных ферментов обеспечивает дополнительное использование непереваримой фракции. Достичь полной переваримости кормов невозможно, хотя  in vitro экзогенные ферменты переваривают почти до 100% целевых субстратов. Проблема обусловлена тем, что в  естественных кормах нет чистых субстратов — они связаны с другими веществами, которые ограничивают доступность к ним ферментов. Свойства естественных субстратов, их  концентрация и доступность даже в одном и том же сырье  изменчивы, что исключает надежное прогнозирование  эффективности действия кормовых ферментов. Частично эти трудности преодолевают путем использования  полиферментных препаратов. Необходимо дальнейшее изучение специфики нативных субстратов и факторов, повышающих их доступность для действия ферментов.  </p></abstract><trans-abstract xml:lang="en"><p> In animal feeding enzyme preparations are mainly used, which are not produced in the body of animals, although in chickens in the first weeks of life and piglets after weaning an insufficient amount of their own proteases and amylases is formed, so their inclusion in feed is also useful. By now highly active enzyme preparations with various specific activities have been created and are being produced. In feeds prepared using traditional raw materials up to 30% of nutrients are not available for digestion by enzymes secreted in the gastrointestinal tract. The inclusion of exogenous enzymes in the feed provides additional use of the indigestible fraction. It is impossible to achieve complete digestibility of feed, although in vitro exogenous enzymes digest almost 100% of the target substrates. The problem is due to the fact that natural feed does not contain pure substrates — they are associated with other substances that  limit the availability of enzymes to them. The properties of natural substrates, their concentration and availability even in the same raw material are variable, which excludes reliable prediction of the effectiveness of the action of feed enzymes. Partially these difficulties are overcomed by the use of polyenzyme drugs. It is necessary to further study the specificity of native substrates and factors that increase their availability for the action of enzymes. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>ферментные препараты</kwd><kwd>карбоксилазы</kwd><kwd>протеазы</kwd><kwd>фитазы</kwd><kwd>переваримость</kwd><kwd>эффективность использования</kwd></kwd-group><kwd-group xml:lang="en"><kwd>enzyme preparations</kwd><kwd>carbohydrases</kwd><kwd>proteases</kwd><kwd>phytases</kwd><kwd>digestibility</kwd><kwd>efficiency of use</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Крюков В.С, Глебова И.В., Антипов А.А. Оценка действия фитаз в пищеварительном тракте и использование препаратов фитазы в питании животных (обзор). Проблемы биологии продуктивных животных. 2019, 2: 19–43.</mixed-citation><mixed-citation xml:lang="en">Kryukov, V. S, Glebova, I. V., and Antipov, A. 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