<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vetpress</journal-id><journal-title-group><journal-title xml:lang="ru">Аграрная наука</journal-title><trans-title-group xml:lang="en"><trans-title>Agrarian science</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-8155</issn><issn pub-type="epub">2686-701X</issn><publisher><publisher-name>Редакция журнала "Аграрная наука"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.32634/0869-8155-2021-351-7-8-68-70</article-id><article-id custom-type="elpub" pub-id-type="custom">vetpress-1727</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОРМЛЕНИЕ И КОРМОПРОИЗВОДСТВО С/Х ЖИВОТНЫХ</subject></subj-group></article-categories><title-group><article-title>Влияние альфа-монолаурина на продуктивность свиней на откорме в промышленных условиях</article-title><trans-title-group xml:lang="en"><trans-title>Effect of alpha-monolaurin on perfomance of fattening pigs under industrial conditions</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потапова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Potapova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Москва, Дмитровское ш., 163а, корп.2 , 127495</p></bio><bio xml:lang="en"><p>Moscow, Dmitrovskoe sh., 163a, building 2, 127495</p></bio><email xlink:type="simple">info@vitomek.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Журавлев</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhuravlev</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Москва, ул. Тимирязевская, 49, 127550</p></bio><bio xml:lang="en"><p>Moscow, st. Timiryazevskaya, 49, 127550</p></bio><email xlink:type="simple">mikhail.sterh@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Буряков</surname><given-names>Н. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Buryakov</surname><given-names>N. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Москва, ул. Тимирязевская, 49, 127550</p></bio><bio xml:lang="en"><p>Moscow, st. Timiryazevskaya, 49, 127550</p></bio><email xlink:type="simple">mikhail.sterh@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Езерская</surname><given-names>Ю. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ezerskaya</surname><given-names>Yu. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Москва, ул. Коптевская, д.6 7, 125239</p></bio><bio xml:lang="en"><p>Moscow, st. Koptevskaya, 67, 125239</p></bio><email xlink:type="simple">ye@misma.pro</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ООО «ВитОМЭК»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>LLC “VitOMEK”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>РГАУ — МСХА имени К.А. Тимирязева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>RSAU – MAA named after K.A. Timiryazev</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ООО «Мисма Про»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>LLC “Misma Pro”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>23</day><month>09</month><year>2021</year></pub-date><volume>0</volume><issue>7-8</issue><fpage>68</fpage><lpage>70</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Потапова Л.В., Журавлев М.С., Буряков Н.П., Езерская Ю.А., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Потапова Л.В., Журавлев М.С., Буряков Н.П., Езерская Ю.А.</copyright-holder><copyright-holder xml:lang="en">Potapova L.V., Zhuravlev M.S., Buryakov N.P., Ezerskaya Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vetpress.ru/jour/article/view/1727">https://www.vetpress.ru/jour/article/view/1727</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Моноглицериды органических кислот рассматриваются как перспективная замена кормовых антибиотиков в рационах свиней и птиц, так какони обладают выраженными бактериостатическими и бактерицидными свойствами. Одним из самых перспективных соединений является альфа-монолаурин, обладающий значительным антибактериальным действием на грамположительные микроорганизмы.</p></sec><sec><title>Методы</title><p>Методы. Опыт проведен на одном из свинокомплексов Ростовской области 5–27 сентября 2020 г. на свиньях на откорме весом от 36 кг и до достижения живой массы в 75 кг. Поросята опытной группы в составе премикса для комбикорма марки СК-5 получали 0,4 кг/т альфа-монолаурина. В условиях производственной площадки проводились контрольные взвешивания перед началом и по завершении опыта. Фиксировали показатели прироста живой массы за период опыта, потребление корма, сохранность, конверсию корма.</p></sec><sec><title>Результаты</title><p>Результаты. Изучена возможность применения альфа-моноглицерида лауриновой кислоты (GML, глицерол монолаурат) в рационе свиней первого периода откорма в условиях действующего свинокомплекса. Установлено, что альфа-монолаурин улучшает конверсию корма, снижает потребление корма, а также увеличивает сохранность свиней на откорме. Применение альфа-монолаурина привело к увеличению экономической эффективности выращивания свиней на 37,63 руб./гол., или на каждый вложенный рубль было получено 2,38 рубля прибыли.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Monoglycerides of organic acids are considered as a promising replacement for feed antibiotics in the diets of pigs and poultry, as they have pronounced bacteriostatic and bactericidal properties. Alpha-monolaurin is a one of the most promising compound, which has a significant antibacterial effect on gram-positive microorganisms.</p></sec><sec><title>Methods</title><p>Methods. The experiment was carried out at one of the pig farms of the Rostov region on September 5–27, 2020 on fattening pigs weighing from 36 kg and up to achievinga live weight of 75 kg. Piglets of the experimental group received 0.4 kg/t of alpha-monolaurin as part of the premix for compound feed CK-5. In the conditions of the production site, control weighing was carried out before the beginning and at the end of the experiment. Weight gain, feed consumption, survival rate and feed conversion were recorded.</p></sec><sec><title>Results</title><p>Results. The possibility of using alpha-monoglyceride lauric acid (GML, glycerol monolaurate) in the ration of pigs of the first period of fattening under the industrial conditions of an operating pig farm has been studied. It has been found that alphamonolaurin improves feed conversion, reduces feed intake, and also increases the survival rate of fattening pigs. The use of alpha-monolaurin led to an increase in the economic efficiency of raising pigs by 37.63 rubles/head, or 1:2.38 ROI.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>альфа-монолаурин</kwd><kwd>лауриновая кислота</kwd><kwd>СЦЖК</kwd><kwd>кормовые добавки</kwd><kwd>свиноводство</kwd><kwd>свиньи на откорме</kwd><kwd>альтернативы антибиотикам</kwd></kwd-group><kwd-group xml:lang="en"><kwd>alpha-monolaurin</kwd><kwd>lauric acid</kwd><kwd>SCFA</kwd><kwd>feed additives</kwd><kwd>pig production</kwd><kwd>fattening pigs</kwd><kwd>antibiotic alternatives</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Adil, S., Banday, M. T., Bhat, G. A., &amp; Mir, M. S. Alternative strategies to antibiotic growth promoters-A review. Vet Scan | Online Veterinary Medical Journal, 2011;6(1), 76-76.</mixed-citation><mixed-citation xml:lang="en">Adil, S., Banday, M. T., Bhat, G. A., &amp; Mir, M. S. Alternative strategies to antibiotic growth promoters-A review. Vet Scan | Online Veterinary Medical Journal, 2011;6(1), 76-76.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Suiryanrayna, M. V., &amp; Ramana, J. V. A review of the effects of dietary organic acids fed to swine. Journal of animal science and biotechnology, 2015;6(1), 1-11.</mixed-citation><mixed-citation xml:lang="en">Suiryanrayna, M. V., &amp; Ramana, J. V. A review of the effects of dietary organic acids fed to swine. Journal of animal science and biotechnology, 2015;6(1), 1-11.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Cochrane, R. A., Dritz, S. S., Woodworth, J. C., Huss, A. R., Stark, C. R., Saensukjaroenphon, M. &amp; Jones, C. K. Evaluating the Inclusion Level of Medium Chain Fatty Acids to Reduce the Risk of Porcine Epidemic Diarrhea Virus in Complete Feed and SprayDried Animal Plasma. Kansas Agricultural Experiment Station Research Reports, 2016;2(8), 2.</mixed-citation><mixed-citation xml:lang="en">Cochrane, R. A., Dritz, S. S., Woodworth, J. C., Huss, A. R., Stark, C. R., Saensukjaroenphon, M. &amp; Jones, C. K. Evaluating the Inclusion Level of Medium Chain Fatty Acids to Reduce the Risk of Porcine Epidemic Diarrhea Virus in Complete Feed and SprayDried Animal Plasma. Kansas Agricultural Experiment Station Research Reports, 2016;2(8), 2.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Gebhardt, J. T., Thomson, K. A., Woodworth, J. C., Dritz, S. S., Tokach, M. D., DeRouchey, J. M., &amp; Burkey, T. E. Effect of dietary medium-chain fatty acids on nursery pig growth performance, fecal microbial composition, and mitigation properties against porcine epidemic diarrhea virus following storage. Journal of animal science, 2020;98(1), 358.</mixed-citation><mixed-citation xml:lang="en">Gebhardt, J. T., Thomson, K. A., Woodworth, J. C., Dritz, S. S., Tokach, M. D., DeRouchey, J. M., &amp; Burkey, T. E. Effect of dietary medium-chain fatty acids on nursery pig growth performance, fecal microbial composition, and mitigation properties against porcine epidemic diarrhea virus following storage. Journal of animal science, 2020;98(1), 358.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Fortuoso, B. F., Dos Reis, J. H., Gebert, R. R., Barreta, M., Griss, L. G., Casagrande, R. A. &amp; Da Silva, A. S. Glycerol monolaurate in the diet of broiler chickens replacing conventional antimicrobials: Impact on health, performance and meat quality. Microbial pathogenesis, 2019;129, 161-167.</mixed-citation><mixed-citation xml:lang="en">Fortuoso, B. F., Dos Reis, J. H., Gebert, R. R., Barreta, M., Griss, L. G., Casagrande, R. A. &amp; Da Silva, A. S. Glycerol monolaurate in the diet of broiler chickens replacing conventional antimicrobials: Impact on health, performance and meat quality. Microbial pathogenesis, 2019;129, 161-167.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hegde, B. M. Coconut oil–ideal fat next only to mother’s milk (scanning coconut’s horoscope). Journal, Indian Academy of clinical medicine, 2006;7(1), 16-19.</mixed-citation><mixed-citation xml:lang="en">Hegde, B. M. Coconut oil–ideal fat next only to mother’s milk (scanning coconut’s horoscope). Journal, Indian Academy of clinical medicine, 2006;7(1), 16-19.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Oo, K. C., &amp; Stumpf, P. K. Some enzymic activities in the germinating oil palm (Elaeis guineensis) seedling. Plant physiology, 1983;73(4), 1028-1032.</mixed-citation><mixed-citation xml:lang="en">Oo, K. C., &amp; Stumpf, P. K. Some enzymic activities in the germinating oil palm (Elaeis guineensis) seedling. Plant physiology, 1983;73(4), 1028-1032.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Clarke, N. M. &amp; May, J. T. Effect of antimicrobial factors in human milk on rhinoviruses and milk-borne cytomegalovirus in vitro. Journal of medical microbiology, 2000;49(8), 719-723.</mixed-citation><mixed-citation xml:lang="en">Clarke, N. M. &amp; May, J. T. Effect of antimicrobial factors in human milk on rhinoviruses and milk-borne cytomegalovirus in vitro. Journal of medical microbiology, 2000;49(8), 719-723.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Milne, G. W. Gardner's commercially important chemicals: synonyms, trade names, and properties. John Wiley &amp; Sons 2005. 1177 p.</mixed-citation><mixed-citation xml:lang="en">Milne, G. W. Gardner's commercially important chemicals: synonyms, trade names, and properties. John Wiley &amp; Sons 2005. 1177 p.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Isaacs, C. E., Kim, K. S. &amp; Thormar, H. Inactivation of enveloped viruses in human bodily fluids by purified lipids. Annals of the New York Academy of Sciences, 1994;724, 457-464.</mixed-citation><mixed-citation xml:lang="en">Isaacs, C. E., Kim, K. S. &amp; Thormar, H. Inactivation of enveloped viruses in human bodily fluids by purified lipids. Annals of the New York Academy of Sciences, 1994;724, 457-464.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Schlievert, P. M., Deringer, J. R., Kim, M. H., Projan, S. J., &amp; Novick, R. P. Effect of glycerol monolaurate on bacterial growth and toxin production. Antimicrobial agents and chemotherapy, 1992;36(3), 626-631.</mixed-citation><mixed-citation xml:lang="en">Schlievert, P. M., Deringer, J. R., Kim, M. H., Projan, S. J., &amp; Novick, R. P. Effect of glycerol monolaurate on bacterial growth and toxin production. Antimicrobial agents and chemotherapy, 1992;36(3), 626-631.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Vetter, S. M., &amp; Schlievert, P. M. Glycerol monolaurate inhibits virulence factor production in Bacillus anthracis. Antimicrobial agents and chemotherapy, 2005;49(4), 1302-1305.</mixed-citation><mixed-citation xml:lang="en">Vetter, S. M., &amp; Schlievert, P. M. Glycerol monolaurate inhibits virulence factor production in Bacillus anthracis. Antimicrobial agents and chemotherapy, 2005;49(4), 1302-1305.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Projan, S. J., Brown-Skrobot, S., Schlievert, P. M., Vandenesch, F., &amp; Novick, R. P. Glycerol monolaurate inhibits the production of beta-lactamase, toxic shock toxin-1, and other staphylococcal exoproteins by interfering with signal transduction. Journal of bacteriology, 1994;176(14), 4204-4209.</mixed-citation><mixed-citation xml:lang="en">Projan, S. J., Brown-Skrobot, S., Schlievert, P. M., Vandenesch, F., &amp; Novick, R. P. Glycerol monolaurate inhibits the production of beta-lactamase, toxic shock toxin-1, and other staphylococcal exoproteins by interfering with signal transduction. Journal of bacteriology, 1994;176(14), 4204-4209.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Li, Q., Estes, J. D., Schlievert, P. M., Duan, L., Brosnahan, A. J., Southern, P. J &amp; Haase, A. T. Glycerol monolaurate prevents mucosal SIV transmission. Nature, 2009;458(7241), 1034-1038.</mixed-citation><mixed-citation xml:lang="en">Li, Q., Estes, J. D., Schlievert, P. M., Duan, L., Brosnahan, A. J., Southern, P. J &amp; Haase, A. T. Glycerol monolaurate prevents mucosal SIV transmission. Nature, 2009;458(7241), 1034-1038.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Thormar, H., Isaacs, C. E., Brown, H. R., Barshatzky, M. R., &amp; Pessolano, T. Inactivation of enveloped viruses and killing of cells by fatty acids and monoglycerides. Antimicrobial agents and chemotherapy, 1987;31(1), 27-31.</mixed-citation><mixed-citation xml:lang="en">Thormar, H., Isaacs, C. E., Brown, H. R., Barshatzky, M. R., &amp; Pessolano, T. Inactivation of enveloped viruses and killing of cells by fatty acids and monoglycerides. Antimicrobial agents and chemotherapy, 1987;31(1), 27-31.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Thormar, H., Isaacs, C. E., Kim, K. S., &amp; Brown, H. R. Inactivation of visna virus and other enveloped viruses by free fatty acids and monoglycerides. Annals of the New York Academy of Sciences, 1994;724, 465-471.</mixed-citation><mixed-citation xml:lang="en">Thormar, H., Isaacs, C. E., Kim, K. S., &amp; Brown, H. R. Inactivation of visna virus and other enveloped viruses by free fatty acids and monoglycerides. Annals of the New York Academy of Sciences, 1994;724, 465-471.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Schlievert PM, Peterson ML. Glycerol monolaurate antibacterial activity in broth and biofilm cultures. PLoS One. 2012;7(7), e40350.</mixed-citation><mixed-citation xml:lang="en">Schlievert PM, Peterson ML. Glycerol monolaurate antibacterial activity in broth and biofilm cultures. PLoS One. 2012;7(7), e40350.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Kabara, J. J. Antimicrobial agents derived from fatty acids. Journal of the American Oil Chemists' Society, 1984;61(2), 397- 403.</mixed-citation><mixed-citation xml:lang="en">Kabara, J. J. Antimicrobial agents derived from fatty acids. Journal of the American Oil Chemists' Society, 1984;61(2), 397- 403.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
