vetpressАграрная наукаAgrarian science0869-81552686-701XРедакция журнала "Аграрная наука"10.32634/0869-8155-2022-355-1-24-29vetpress-1925Research ArticleТЕРАПИЯ ЖИВОТНЫХANIMALS’ THERAPYОценка эффективности терапии компенсированного дисбактериоза кишечника у кошекEvaluation of the effectiveness of therapy for compensated intestinal dysbiosis in catsВатниковЮ. А.VatnikovYu. A.

Ватников Юрий Анатольевич, доктор ветеринарных наук, профессор, директор Департамента ветеринарной медицины

117198, г. Москва, ул. Миклухо-Маклая, 6

Vatnikov Yuri A., Doctor of Veterinary Sciences, Professor, Director of the Department of Veterinary Medicine

117198, Moscow, st. Miklukho-Maclay, 6

РуденкоП. А.RudenkoP. A.

Руденко Павел Анатольевич, доктор ветеринарных наук, доцент Департамента ветеринарной медицины

117198, г. Москва, ул. Миклухо-Маклая, 6, 

109472, г. Москва, ул. Ак. Скрябина, 23

Rudenko Pavel A., Doctor of Veterinary Sciences, Associate Professor of the Department of Veterinary Medicine

117198, Moscow, st. Miklukho-Maclay, 6, 

109472, Moscow, Academician Skryabin street, 23

БугровН. С.BugrovN. S.

Бугров Николай Сергеевич, аспирант Департамента ветеринарной медицины

117198, г. Москва, ул. Миклухо-Маклая, 6

Bugrov Nikolai S., Post-graduate Student of the Department of Veterinary Medicine

117198, Moscow, st. Miklukho-Maclay, 6

РуденкоА. А.RudenkoA. A.

Руденко Андрей Анатольевич, доктор ветеринарных наук, профессор кафедры ветеринарной медицины

125080, г. Москва, Волоколамское ш., 11

Rudenko Andrey A., Doctor of Veterinary Sciences, Professor of the Department of Veterinary Medicine

125080, Moscow, Volokolamskoe sh., 11

Российский университет дружбы народовРоссияPeoples’ Friendship University of RussiaRussian FederationРоссийский университет дружбы народов; Московская государственная академия ветеринарной медицины и биотехнологии — МВА им. К.И. СкрябинаРоссияPeoples’ Friendship University of Russia; Moscow State Academy of Veterinary Medicine and Biotechnology — MVA named after K.I. ScryabinRussian FederationФГБОУ ВО «Московский государственный университет пищевых производств»РоссияFGBOU VO “Moscow State University of Food Production”Russian Federation202228022022012429Copyright © Ватников Ю.А., Руденко П.А., Бугров Н.С., Руденко А.А., 20222022Ватников Ю.А., Руденко П.А., Бугров Н.С., Руденко А.А.Vatnikov Y.A., Rudenko P.A., Bugrov N.S., Rudenko A.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.vetpress.ru/jour/article/view/1925Актуальность

Актуальность. Несмотря на постоянное совершенствование методов коррекции микробиоты кишечника, частота возникновения дисбактериозов при различных патологических процессах не только не уменьшается, а наоборот, увеличивается. Поэтому выбор оптимальной терапевтической схемы при коррекции наиболее легкой компенсированной степени дисбактериоза кишечника у кошек, на наш взгляд, является актуальным направлением научных исследований в ветеринарии.

Методы

Методы. Дана оценка эффективности фармакотерапии кошек с компенсированным дисбактериозом кишечника (n = 15). Животные были разделены методом конвертов на две опытные группы: А1 (n = 6) и А2 (n = 9). Показана динамика отдельных гематологических и иммунологических показателей крови кошек при дисбактериозе 1-й степени в процессе их терапии (до лечения, на 7-е и 14-е сутки).

Результаты

Результаты. При компенсированном дисбактериозе кишечника у кошек назначение диетического корма Purina Pro Plan показывает терапевтический эффект, что приводит к общему клиническому улучшению уже через 6,16±0,60 суток. Однако применение пробиотика «Лактобифадола» на фоне диетотерапии нормализует аппетит через 2,39 суток, неприятный запах из ротовой полости через 0,84 суток, стул через 0,89 суток, ускоряет общее клиническое улучшение животных при кишечном дисбактериозе 1-й степени на 2,16 суток раньше при сравнении с показателями кошек группы А1.

 

 

Relevance

Relevance. Despite the constant improvement of methods for correcting the intestinal microbiota, the occurrence of dysbacteriosis in various pathological processes not only does not decrease, but, on the contrary, increases. Therefore, the choice of the optimal therapeutic regimen for the correction of the lightest compensated degree of intestinal dysbiosis in cats, in our opinion, is an urgent direction of scientific research in veterinary medicine.

Methods

Methods. Evaluation of the effectiveness of pharmacotherapy in cats with compensated intestinal dysbiosis (n = 15) is given. The animals were divided by the envelope method into two experimental groups: A1 (n = 6) and A2 (n = 9). The dynamics of individual hematological and immunological blood parameters of cats with grade 1 dysbiosis in the course of their therapy (before treatment, on days 7 and 14) is shown.

Results

Results. With compensated intestinal dysbiosis in cats, the appointment of the Purina Pro Plan dietary food shows a therapeutic effect, which leads to an overall clinical improvement as early as after 6.16±0.60 days. However, the use of the probiotic «Lactobifadol» against the background of diet therapy normalizes appetite after 2.39 days, an unpleasant odor from the oral cavity after 0.84 days, feces after 0.89 days, accelerates the overall clinical improvement of animals with intestinal dysbiosis of the 1st degree by 2.16 days earlier, when compared with the indicators of cats of the A1 group.

 

 

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The authors declare that there are no conflicts of interest present.