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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vetpress</journal-id><journal-title-group><journal-title xml:lang="ru">Аграрная наука</journal-title><trans-title-group xml:lang="en"><trans-title>Agrarian science</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-8155</issn><issn pub-type="epub">2686-701X</issn><publisher><publisher-name>Редакция журнала "Аграрная наука"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.32634/0869-8155-2023-373-8-41-47</article-id><article-id custom-type="elpub" pub-id-type="custom">vetpress-2745</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗООТЕХНИЯ И ВЕТЕРИНАРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ZOOTECHNICS AND VETERINARY MEDICINE</subject></subj-group></article-categories><title-group><article-title>Анализ взаимосвязи компонентного состава молока и биомаркеров крови голштинизированных коров</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of the relationship between the component composition of milk and blood biomarkers of Holsteinized cows</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9021-1404</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карликова</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Karlikova</surname><given-names>G. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галина Геннадьевна Карликова, доктор сельскохозяйственных наук, старший научный сотрудник отдела популяционной генетики и  генетических основ разведения животных</p><p>пос. Дубровицы, д. 60, Подольск, Московская обл.,142132, Россия</p></bio><bio xml:lang="en"><p>Galina Gennadievna Karlikova, Doctor of Agricultural Sciences, Senior Researcher Department of Population Genetics and Genetic Basis of Animal Breeding</p><p>60 Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132, Russia </p></bio><email xlink:type="simple">karlikovagalina@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лашнева</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lashneva</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ирина Алексеевна Лашнева, ведущий специалист отдела популяционной генетики и генетических основ разведения животных</p><p>пос. Дубровицы, д. 60, Подольск, Московская обл.,142132, Россия</p><p>https://orcid.org/0000-0009-4276-8782</p></bio><bio xml:lang="en"><p>Irina Alekseevna Lashneva, Leading Specialist Department of Population Genetics and Genetic Basis of Animal Breeding</p><p>60 Dubrovitsy, Podolsk Municipal District, Moscow Region,142132, Russia</p><p>https://orcid.org/0000-0009-4276-8782 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1799-6014</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сермягин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sermyagin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Александрович Сермягин, кандидат сельскохозяйственных наук, заведующий отделом популяционной генетики и генетических основ разведения животных</p><p>пос. Дубровицы, д. 60, Подольск, Московская обл.,142132, Россия</p></bio><bio xml:lang="en"><p>Alexander Alexandrovich Sermyagin, Candidate of Agricultural Sciences, Head of the Department of Population Genetics and Genetic Basis of Animal Breeding</p><p>60 Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132, Russia </p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральный исследовательский центр животноводства — ВИЖ им. академика Л.К. Эрнста</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Research Center for Animal Husbandry named after Academy Member L.K. Ernst</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>27</day><month>08</month><year>2023</year></pub-date><volume>1</volume><issue>8</issue><fpage>41</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Карликова Г.Г., Лашнева И.А., Сермягин А.А., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Карликова Г.Г., Лашнева И.А., Сермягин А.А.</copyright-holder><copyright-holder xml:lang="en">Karlikova G.G., Lashneva I.A., Sermyagin A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vetpress.ru/jour/article/view/2745">https://www.vetpress.ru/jour/article/view/2745</self-uri><abstract><p>Поиск потенциальных биомаркеров, сигнализирующих о состоянии физиологического статуса организма высокопродуктивных коров, учитываемых в дальнейшей селекции, направленной на увеличение количества и качества молочных продуктов, становится актуальным во многих странах, занимающихся молочным скотоводством.Исследование проведено на базе племенного завода «Ладожский» (Краснодарский край) — филиала ФГБНУ «ФИЦ ВИЖ им. Л.К. Эрнста». Исследования проб крови проведены на автоматическом биохимическом и иммуноферментном анализаторе Chem Well. Анализ расширенного компонентного состава молока сделан на анализаторе Combi Foss 7 (ИФС).По результатам исследований рассчитаны взаимосвязи компонентного состава молока и крови коров. Для суточного удоя умеренные положительные корреляции отмечались с фосфолипидами (r = 0,364), холестерином (r = 0,324), альбумином (r = 0,316) и магнием (r = 0,309). Умеренная взаимосвязь между холестерином и лактозой составила r = 0,408 и между холестерином и СОМО — r = 0,307. Прямая умеренная взаимосвязь r = 0,376 между лактозой и АЛТ, r = 0,361 — альбумином, r = 0,455 — фосфолипидами. Умеренная прямая корреляция между трансизомерами и щелочной фосфатазой составила r = 0,309, хлором — r = 0,259. Умеренные обратные корреляции проявились в отношении «суточный удой — эритроциты» r = 0,312. Умеренные обратные корреляции между трансизомерами и холестерином r = -0,385, мочевиной — r = -0,428. Взаимосвязи остальных компонентов молока и крови (как прямые, так и обратные) оказались слабыми и очень слабыми.</p></abstract><trans-abstract xml:lang="en"><p>The search for potential biomarkers that signal the state of the physiological status of the organism of highly productive cows, which are taken into account in further selection aimed at increasing the quantity and quality of dairy products, is becoming relevant in many countries engaged in dairy cattle breeding. The study was conducted on the basis of the Ladozhsky breeding plant (Krasnodar Krai) — a branch of the L.K. Ernst Federal State Budgetary Institution. Studies of blood samples were carried out on an automatic biochemical and enzyme immunoassay analyzer «Chem Well». The analysis of the expanded component composition of milk was made on the analyzer «Combi Foss 7» (IFS). Based on the results of the studies, we calculated the relationship between the component composition of milk and blood of cows. For daily milk yield, moderate positive correlations were observed with phospholipids r = 0.364, cholesterol r = 0.324, albumin r = 0.316 and magnesium r = 0.309. Moderate relationship between cholesterol and lactose was r = 0.408 and between cholesterol and SOMO r = 0.307. Direct moderate relationship r = 0.376 between lactose and ALT, r = 0.361 — albumin, r = 0.455 — phospholipids. Moderate direct correlation between trans-isomers and alkaline phosphatase was r = 0.309, chlorine — r = 0.259. Moderate inverse correlations appeared in relation to daily milk yield — erythrocytes r = 0.312. Moderate inverse correlations between transisomers and cholesterol r = -0.385, urea r = -0.428. The relationships of other components of milk and blood, both direct and inverse, turned out to be weak and very weak.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>крупный рогатый скот</kwd><kwd>молоко</kwd><kwd>биомаркер</kwd><kwd>селекция</kwd><kwd>генетический потенциал</kwd><kwd>жирные кислоты молока</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cattle</kwd><kwd>milk</kwd><kwd>biomarker</kwd><kwd>selection</kwd><kwd>genetic potential</kwd><kwd>milk fatty acids</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бондаренко Г.А. Метаболические тесты у крупного рогатого скота и перспективы их использования для повышения молочной продуктивности. Сельскохозяйственная биология. 1983; (10): 108–115.</mixed-citation><mixed-citation xml:lang="en">Bondarenko G.A. Metabolic tests in cattle and prospects for their use to increase milk productivity. 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