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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vetpress</journal-id><journal-title-group><journal-title xml:lang="ru">Аграрная наука</journal-title><trans-title-group xml:lang="en"><trans-title>Agrarian science</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-8155</issn><issn pub-type="epub">2686-701X</issn><publisher><publisher-name>Редакция журнала "Аграрная наука"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.32634/0869-8155-2024-379-2-44-47</article-id><article-id custom-type="elpub" pub-id-type="custom">vetpress-2935</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВЕТЕРИНАРИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>VETERINARY MEDICINE</subject></subj-group></article-categories><title-group><article-title>Изменчивость метаболических маркеров в крови у молочных коз с разной динамикой удоя в первой половине лактации</article-title><trans-title-group xml:lang="en"><trans-title>Variability of metabolic markers in the blood of dairy goats with different dynamics of milk yield in the first half of lactation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7017-9988</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лейбова</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Leibova</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виктория Борисовна Лейбова – кандидат биологических наук </p><p>Московское шоссе, 55А, Пушкин, Санкт-Петербург, 196601</p></bio><bio xml:lang="en"><p>Victoriia Borisovna Leibova – Candidate of Biological Sciences </p><p>55А Moskovskoe Shosse, Pushkin, St. Petersburg, 196601</p></bio><email xlink:type="simple">leib1406@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8658-2026</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Позовникова</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pozovnikova</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Марина Владимировна Позовникова – кандидат биологических наук </p><p>Московское шоссе, 55А, Пушкин, Санкт-Петербург, 196601</p></bio><bio xml:lang="en"><p>Marina Vladimirovna Pozovnikova – Candidate of Biological Sciences </p><p>55А Moskovskoe Shosse, Pushkin, St. Petersburg, 196601</p></bio><email xlink:type="simple">pozovnikova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Всероссийский научно-исследовательский институт генетики и разведения сельскохозяйственных животных — филиал ФГБНУ «Федеральный исследовательский центр животноводства — ВИЖ им. академика Л.К. Эрнста<country>Россия</country></aff><aff xml:lang="en">The All-Russian Scientific Research Institute of Genetics and Breeding of Farm Animals is a branch of the L.K. Ernst Federal Research Center for Animal Husbandry<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><fpage>44</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лейбова В.Б., Позовникова М.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Лейбова В.Б., Позовникова М.В.</copyright-holder><copyright-holder xml:lang="en">Leibova V.B., Pozovnikova M.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vetpress.ru/jour/article/view/2935">https://www.vetpress.ru/jour/article/view/2935</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. Цель исследования — изучение биохимического профиля крови в первые три месяца после окота у коз-первокоток с разной динамикой удоя в первую половину лактации.</p></sec><sec><title>Методы</title><p>Методы. Работу проводили в хозяйстве с интенсивной технологией содержания коз зааненской породы (Ленинградская обл.). Отбор проб крови осуществляли в весенне-летний период: на 20–30-е сутки, 50–60-е сутки и 80–90-е сутки после окота. В сыворотке крови определяли концентрацию общего белка, альбумина, мочевины, креатинина, глюкозы, общего холестерина, триглицеридов. Для анализа биохимического профиля крови по окончании 4-го месяца лактации козы были разделены на две группы. В группу I (n = 9) вошли животные, достигшие максимального удоя во 2-м месяце лактации, к группе II (n = 8) отнесены особи с выходом на пик удоя в 3-м месяце лактации.</p></sec><sec><title>Результаты</title><p>Результаты. Удой за первые три месяца после окота не имел различий между группами. На 4-й месяц лактации удой был на 22,3% выше в группе II (pAdjusted &lt; 0,05). По двум из семи биохимических показателей крови было выявлено различие: в группе I концентрация глюкозы в крови на 50–60-е сутки после окота была на 7,7% ниже (pAdjusted &lt; 0,05), а содержание сывороточного креатинина на 80–90-е сутки — на 10,1% выше (pAdjusted &lt; 0,01) по сравнению с группой II. Данные различия могут быть обусловлены особенностями адаптации к метаболической нагрузке у коз-первокоток с разным временным периодом от окота до выхода на максимальный удой.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. The aim of the study was to study the biochemical profile of blood in the first three months after lambing in first-year goats with different dynamics of milk yield in the first half of lactation.</p></sec><sec><title>Methods</title><p>Methods. The work was carried out on a farm with intensive technology for keeping goats of the Zaanen breed (Leningrad region). Blood sampling was carried out in the spring and summer period: on the 20th– 30th day, 50–60 days and 80–90 days after lambing. The concentration of total protein, albumin, urea, creatinine, glucose, total cholesterol, and triglycerides was determined in the blood serum. To analyze the biochemical profile of the blood at the end of the 4th month of lactation, the goats were divided into two groups. Group I (n = 9) included animals that reached maximum milk yield in the 2nd month of lactation, group II (n = 8) included individuals with peak milk yield in the 3rd month of lactation. Milk yield for the first three months after lambing did not differ between the groups.</p></sec><sec><title>Results</title><p>Results. At the 4th month of lactation, milk yield was 22.3% higher in group II (pAdjusted &lt; 0.05). Two of the seven biochemical blood parameters showed a difference: in group I, the blood glucose concentration on the 50–60 days after lambing was 7.7% lower (pAdjusted &lt; 0.05), and the serum creatinine content on the 80–90 days was 10.1% higher (pAdjusted &lt; 0.01) compared with group II. These differences may be due to the peculiarities of adaptation to metabolic load in first-year goats with different time periods from lambing to reaching maximum milk yield.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>козы</kwd><kwd>лактационная кривая</kwd><kwd>биохимический профиль крови</kwd><kwd>креатинин</kwd><kwd>глюкоза</kwd></kwd-group><kwd-group xml:lang="en"><kwd>goats</kwd><kwd>lactation curve</kwd><kwd>biochemical blood profile</kwd><kwd>creatinine</kwd><kwd>glucose</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Работа выполнена в рамках Государственного задания по проекту № 124020200029-4.</funding-statement></funding-group><funding-group xml:lang="en"><funding-statement>The research was carried out within the framework of the State assignment for project No. 124020200029-4.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Солоднева Е.В., Смольников Р.В., Баженов С.А., Воробьева Д.А., Столповский Ю.А. 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