vetpressАграрная наукаAgrarian science0869-81552686-701XРедакция журнала "Аграрная наука"10.32634/0869-8155-2024-380-3-66-71vetpress-2982Research ArticleВЕТЕРИНАРИЯVETERINARY MEDICINEМикробный пейзаж при остром гнойно-катаральном послеродовом эндометрите у коровMicrobial landscape in acute purulent-catarrhal postpartum endometritis in cowshttps://orcid.org/0009-0003-4668-2545ЛуцайВ. И.LutsayV. I.

Владимир Иванович Луцай, доктор ветеринарных наук, заведующий кафедрой ветеринарной медицины

Волоколамское шоссе, 11, Москва, 125080

Vladimir Ivanovich Lutsaу, Doctor of Veterinary Sciences, Head of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080

recaro21@bk.ruhttps://orcid.org/0009-0005-4230-8307СолошенкоН. Ю.SoloshenkoN. Yu.

Наталья Юрьевна Солошенко, директор лаборатории «Виварий» кафедры ветеринарной медицины

Волоколамское шоссе, 11, Москва, 125080

Natalya Yurievna Soloshenko, Director of the laboratory “Vivarium” of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080

soloshenko-n@mail.ruhttps://orcid.org/0009-0002-6908-2895НефедовА. М.NefedovA. M.

Антон Максимович Нефедов, аспирант кафедры ветеринарной медицины

Волоколамское шоссе, 11, Москва, 125080

Anton Maksimovich Nefedov, Postgraduate Student of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080

goose322@mail.ruhttps://orcid.org/0009-0002-5302-3321СибирцевВ. Д.SibirtsevV. D.

Владимир Дмитриевич Сибирцев, аспирант кафедры ветеринарной медицины

Волоколамское шоссе, 11, Москва, 125080

Vladimir Dmitrievich Sibirtsev, Postgraduate Student of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080

sibircev_vd@mail.ruhttps://orcid.org/0000-0002-6434-3497РуденкоА. А.RudenkoA. A.

Андрей Анатольевич Руденко, доктор ветеринарных наук, профессор кафедры ветеринарной медицины

Волоколамское шоссе, 11, Москва, 125080

Andrey Anatolievich Rudenko, Doctor of Veterinary Sciences, Professor of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080

rudenkoaa@mgupp.ruhttps://orcid.org/0000-0002-0418-9918РуденкоП. А.RudenkoP. A.

Павел Анатольевич Руденко, доктор ветеринарных наук, профессор департамента ветеринарной медицины

Волоколамское шоссе, 11, Москва, 125080

ул. им. Миклухо-Маклая, 6, Москва, 117198

Pavel Anatolievich Rudenko, Doctor of Veterinary Sciences, Professor of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080

6 Miklukho-Maclay Str., Moscow, 117198

pavelrudenko76@yandex.ruРоссийский биотехнологический университет (РОСБИОТЕХ)РоссияRussian Biotechnological UniversityRussian FederationРоссийский биотехнологический университет (РОСБИОТЕХ); Российский университет дружбы народов им. Патриса ЛумумбыРоссияRussian Biotechnological University; Peoples’ Friendship University of RussiaRussian Federation202425032024036671Copyright © Луцай В.И., Солошенко Н.Ю., Нефедов А.М., Сибирцев В.Д., Руденко А.А., Руденко П.А., 20242024Луцай В.И., Солошенко Н.Ю., Нефедов А.М., Сибирцев В.Д., Руденко А.А., Руденко П.А.Lutsay V.I., Soloshenko N.Y., Nefedov A.M., Sibirtsev V.D., Rudenko A.A., Rudenko P.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.vetpress.ru/jour/article/view/2982

Особое место среди факторов окружающей среды, влияющих на организм животных, занимают микроорганизмы — возбудители инфекционных заболеваний. В связи с этим остро стоит проблема циркуляции ассоциаций условно-патогенных микроорганизмов, способных вызывать достаточно широкий спектр патологий у крупного рогатого скота.

В статье приведено изучение микробного фона вагинально-маточного содержимого, отобранного при остром гнойно-катаральном послеродовом эндометрите у коров. Показано, что от 20 коров, больных острым гнойно-катаральным эндометритом, изолированы 58 штаммов условно-патогенных микроорганизмов 13 видов, отнесенных к 6 родам. Чаще всего выделяли культуры St. аureus, E. сoli (серотипов О4, О9 и О83), Str. pyogenes, Str. agalactiae, P. aeruginosa, Str. uberis и Str. faecalis. Чаще развитие острого гнойно-катарального эндометрита у коров обусловливали грамположительные бактерии. Из 58 изолированных штаммов микроорганизмов 22 (37,9%) культуры вызывали гибель белых мышей при их внутрибрюшинном введении. При этом патогенными свойствами чаще обладали грамположительные кокки, а именно представители родов Streptococcus spp. (11— 50,0%) и Staphylococcus spp. (6 — 27,3%) изолятов соответственно. Установлено, что чаще эндометриты вызывают ассоциации условно-патогенных микроорганизмов, в состав которых входили три сочлена — в 14 (50,0%) случаях, реже четыре сочлена — в 7 (25,0%) случаях. Изолированные микроорганизмы были чувствительны лишь к трем антибактериальным препаратам: цефкиному, цефепиму и марбофлоксацину.

A special place among environmental factors affecting the body of animals is occupied by microorganisms— pathogens of infectious diseases. In this regard, the problem of circulation of associations of conditionally pathogenic microorganisms capable of causing a fairly wide range of pathologies in cattle in cattle is acute. The article provides a study of the microbial background of the vaginal-luminous contents selected in the acute purulent-catarrhal postpartum endomethry in cows. It was shown that 58 strains of opportunistic microorganisms of 13 species, classified into 6 genera, were isolated from 20 cows suffering from acute purulent catarrhal endometritis. The most frequently isolated cultures were St. aureus, E. coli (serotypes O4, O9 and O83), Str. pyogenes, Str. agalactiae, P. aeruginosa, Str. uberis and Str. faecalis. Moreover, the development of acute purulent-catarrhal endometritis in cows was more often caused by grampositive bacteria. Of the 58 isolated strains of microorganisms, 22 (37.9%) cultures caused the death of white mice when administered intraperitoneally. At the same time, gram-positive cocci were more likely to have pathogenic properties, namely representatives of the genera Streptococcus spp. (11 — 50.0%) and Staphylococcus spp. (6 — 27.3%) isolates, respectively. It was found that endometritis more often causes associations of opportunistic microorganisms, which included three joints in 14 (50.0%) cases, less often four joints in 7 (25.0%) cases. The isolated microorganisms were sensitive to only three antibacterial drugs: cefkin, cefepime and marbofloxacin.

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The authors declare that there are no conflicts of interest present.