vetpressАграрная наукаAgrarian science0869-81552686-701XРедакция журнала "Аграрная наука"10.32634/0869-8155-2024-380-3-80-84vetpress-2984Research ArticleВЕТЕРИНАРИЯVETERINARY MEDICINEЭффективность применения бактерий рода Bacillus в составе пробиотика Natupro® против штаммов патогенных бактерий in vitroThe effect of Bacillus in the composition of the probiotic Natupro® against bacterial pathogenic strains in vitrohttps://orcid.org/0000-0001-6755-5180ИльяшенкоА. Н.IlyashenkoA. N.

Артур Николаевич Ильяшенко, кандидат биологических наук

ул. Рапуланкату, 2, Каарина, 20780

Arthur Nikolaevich Ilyashenko, Candidate of Biological Sciences, Production and Office

arthur.ilyashenko@bioproton.comBioproton Europe OYФинляндияBioproton Europe OyFinland202425032024038084Copyright © Ильяшенко А.Н., 20242024Ильяшенко А.Н.Ilyashenko A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.vetpress.ru/jour/article/view/2984Актуальность

Актуальность. Использование пробиотиков с пользой для здоровья становится популярным в связи с поиском более безопасных продуктов, обладающих защитным и терапевтическим действием против болезней и инфекционных агентов. Появление и распространение устойчивости к противомикробным препаратам среди патогенных микроорганизмов привели к введению ограничений на нетерапевтическое применение антибиотиков для профилактики и стимулирования роста, особенно в животноводстве. В то время как пробиотики с одним штаммом полезны для здоровья, пробиотики с несколькими штаммами могут быть более полезными из-за синергизма и аддитивных эффектов отдельных изолятов.

Методы

Методы. В данном исследовании была изучена эффективность мультиштаммового пробиотика Natupro в отношении патогенных штаммов бактерий (Escherichia coli 320, Salmonella typhimurium 415, Staphylococcus aureus 12600, Streptococcus uberis 700407, Klebsiella pneumoniae 13883, Listeria monocitogenes 766/20) in vitro.

Результаты

Результаты. По результатам работы было установлено, что штаммы бактерий в составе Natupro® проявляют литическую активность в отношении патогенных штаммов Salmonella typhimurium 415 и Klebsiella pneumoniae 13883 и оказывают бактериостатическое действие на штамм Escherichia coli 320 и Salmonella typhimurium 415.

Relevance

Relevance. The use of probiotics for health benefits is becoming popular because of the quest for safer products with protective and therapeutic effects against diseases and infectious agents. The emergence and spread of antimicrobial resistance among pathogens had prompted restrictions over the nontherapeutic use of antibiotics for prophylaxis and growth promotion, especially in animal husbandry. While single-strain probiotics are beneficial to health, multi-strain probiotics might be more helpful because of synergy and additive effects among the individual isolates.

Methods

Methods. In this study, the effectiveness of the multi-strain probiotic Natupro on pathogenic bacterial strains (Escherichia coli 320, Salmonella typhimurium 415, Staphylococcus aureus 12600, Streptococcus uberis 700407, Klebsiella pneumoniae 13883, Listeria monocitogenes 766/20) in vitro was studied.

Results

Results. According to the results of the work carried out, it was found that the bacterial strains in Natupro® exhibit lytic activity against pathogenic strains of Salmonella typhimurium 415 and Klebsiella pneumoniae 13883 and have a bacteriostatic effect on Escherichia coli strain 320 and Salmonella typhimurium 415.

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The authors declare that there are no conflicts of interest present.