vetpressАграрная наукаAgrarian science0869-81552686-701XРедакция журнала "Аграрная наука"10.32634/0869-8155-2024-386-9-71-76vetpress-3272Research ArticleЗООТЕХНИЯZOOTECHNICSГенетическая архитектура мясных показателей свиноматок крупной белой породыGenetic architecture of meat traits in Large White sowshttps://orcid.org/0000-0002-5208-3376ТребунскихЕ. А.TrebunskikhE. A.

Елена Алексеевна Требунских, заместитель директора по племенному делу

ул. им. Калинина, 1, с. Верхняя Хава, Верхнехавский р-н, Воронежская обл., 396110

Elena Alekseevna Trebunskikh, Deputy Director of Breeding

1 Kalinin Str., Verkhnyaya Khava village, Verkhnekhava district, Voronezh region, 396110

terramio7@mail.ruhttps://orcid.org/0000-0001-7533-4281БелоусА. А.BelousA. A.

Анна Александровна Белоус, кандидат биологических наук, доцент, заведующая лабораторией

пос. Дубровицы, 60, г. о. Подольск, Московская обл., 142132

Anna Alexandrovna Belous, Candidate of Biological Sciences, Associate Professor, Head of the Laboratory

60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132

belousa663@gmail.comhttps://orcid.org/0000-0002-1153-5815ОтрадновП. И.OtradnovP. I.

Пётр Ильич Отраднов, младший научный сотрудник

пос. Дубровицы, 60, г. о. Подольск, Московская обл., 142132

Pyotr Ilyich Otradnov, Junior Researcher

60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132

deriteronard@gmail.comhttps://orcid.org/0000-0003-4877-0883КонтэА. Ф.ConteA. F.

Александр Фёдорович Контэ, кандидат сельскохозяйственных наук, старший научный сотрудник

пос. Дубровицы, 60, г. о. Подольск, Московская обл., 142132

Alexander Fedorovich Conte, Candidate of Agricultural Sciences, Senior Researcher

60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132

alexandrconte@yandex.ruhttps://orcid.org/0000-0002-4874-2615РешетниковаА. А.ReshetnikovaA. A.

Анастасия Александровна Решетникова, младший научный сотрудник

пос. Дубровицы, 60, г. о. Подольск, Московская обл., 142132

Anastasia Alexandrovna Reshetnikova, Junior Research Assistant

60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132

reshetnikova.aa@yandex.ruhttps://orcid.org/0000-0002-2080-0182ВолковаВ. В.VolkovaV. V.

Валерия Владимировна Волкова, кандидат биологических наук, старший научный сотрудник

пос. Дубровицы, 60, г. о. Подольск, Московская обл., 142132

Valeria Vladimirovna Volkova, Candidate of Biological Sciences, Senior Researcher

60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132

moonlit-elf@mail.ruhttps://orcid.org/0000-0003-4017-6863ЗиновьеваН. А.ZinovievaN. A.

Наталия Анатольевна Зиновьева, директор, доктор биологических наук, академик Российской академии наук, профессор

пос. Дубровицы, 60, г. о. Подольск, Московская обл., 142132

Natalia Anatolyevna Zinovieva, Director, Doctor of Biological Sciences, Academician of the Russian  Academy of Sciences, Professor

60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132

priemnaya-vij@mail.ruООО Селекционно-гибридный центр «Топ Ген»РоссияTop Gen Breeding and Hybrid Center LLCRussian FederationФедеральный исследовательский центр животноводства — ВИЖ им. академика Л.К. ЭрнстаРоссияL.K. Ernst Federal Research Center for Animal HusbandryRussian Federation202412102024197176Copyright © Требунских Е.А., Белоус А.А., Отраднов П.И., Контэ А.Ф., Решетникова А.А., Волкова В.В., Зиновьева Н.А., 20242024Требунских Е.А., Белоус А.А., Отраднов П.И., Контэ А.Ф., Решетникова А.А., Волкова В.В., Зиновьева Н.А.Trebunskikh E.A., Belous A.A., Otradnov P.I., Conte A.F., Reshetnikova A.A., Volkova V.V., Zinovieva N.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.vetpress.ru/jour/article/view/3272

В настоящее время полногеномный анализ ассоциаций является современным и достоверным методом анализа геномной информации о животных, а также определения взаимосвязи «генотип — фенотип». Данное исследование направлено на использование метода GWAS для выявления значимых SNP, находящихся внутри или сцепленных с генами по мясным показателям свиней крупной белой породы — толщине шпика над 6–7-м и 10–12-м позвонками, глубине «мышечного глазка». Проведенный GWA-анализ показал наличие 60 генов, из которых 17 имеют связь с биологическим функционалом, аннотация которых проведена в программе DAVID. Были обнаружены три гена, имеющие кодификацию в базе Pig QTL. Гены были разделены на 10 групп на основании генной онтологии (GO). Из всех генов наибольший интерес представляет ген AUTS2, расположенный на 3-й хромосоме и прогнозирующий количество желтых тел у свиноматок. Результаты данной научной работы будут способствовать разработке системы генетической оценки и улучшению мясных качеств свиней.

Currently, genome-wide association analysis is a modern and reliable method for analyzing genomic information about animals, as well as determining the “genotype — phenotype” relationship. This study aims to use the GWAS method to identify significant SNPs located within or linked to genes for meat traits in Large White pigs — backfat thickness over the 6–7th and 10–12th vertebrae, and loin muscle depth. The conducted GWA analysis revealed 60 genes, of which 17 are associated with biological functionality, annotated using the DAVID program. Three genes were found to have codification in the Pig QTL database. The genes were divided into 10 groups based on gene ontology (GO). Of all the genes, the AUTS2 gene, located on chromosome 3 and predicting the number of corpora lutea in sows, is of greatest interest. The results of this scientific work will contribute to the development of a genetic evaluation system and improvement of meat qualities in pigs.

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The authors declare that there are no conflicts of interest present.