vetpressАграрная наукаAgrarian science0869-81552686-701XРедакция журнала "Аграрная наука"10.32634/0869-8155-2025-393-04-28-33vetpress-3569Research ArticleВЕТЕРИНАРИЯVETERINARY MEDICINEДиагностика аритмогенной дисплазии правого желудочка у собак, приводящей к прекапиллярной легочной гипертензииDiagnosis of arrhythmogenic right ventricular dysplasia in dogs leading to precapillary pulmonary hypertensionhttps://orcid.org/0000-0003-3160-8062СпиринаО. А.SpirinaO. A.

Ольга Александровна Спирина, ветеринарный врач

Волоколамское шоссе, 11, Москва, 125080

Olga Alexandrovna Spirina, Veterinarian

11 Volokolamsk Highway, Moscow, 125080

SpirinaOA@gmail.comhttps://orcid.org/0000-0001-7138-6463СотниковаЛ. Ф.SotnikovaL. F.

Лариса Фёдоровна Сотникова, доктор ветеринарных наук, профессор

Волоколамское шоссе, 11, Москва, 125080

Larisa Fedorovna Sotnikova, Doctor of Veterinary Sciences, Professor

11 Volokolamsk Highway, Moscow, 125080

lfsotnikova@mail.ruРоссийский биотехнологический университет (РОСБИОТЕХ)РоссияRussian Biotechnological University (ROSBIOTECH)Russian Federation202525042025142833Copyright © Спирина О.А., Сотникова Л.Ф., 20252025Спирина О.А., Сотникова Л.Ф.Spirina O.A., Sotnikova L.F.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.vetpress.ru/jour/article/view/3569Актуальность

Актуальность. В работе представлен научно обоснованный подход к диагностике аритмогенной дисплазии правого желудочка у собак пород боксер, английский бульдог и метисов данных пород. Актуальность исследования определяется увеличенной частотой встречаемости заболевания, являющегося в дальнейшем (при несвоевременной диагностике) причиной развития легочной гипертензии.

Методы и материалы

Методы и материалы. Использовался комплексно-методический подход, включающий поверхностное клиническое обследование, исследования зоны патологического процесса с помощью методов визуальной диагностики и электрокардиографии. Исследования были проведены на клиническом материале из 25 больных собак в возрасте 5–7 лет пород боксер, английский бульдог и метисов этих пород с симптомами одышки, вялости и потерей сознания. Использовался комплексный диагностический подход, включающий в себя эхокардиографическое обследование, электрокардиографию.

Результаты

Результаты. На основании полученных данных в зависимости от степени тяжести состояния животного определялись наиболее точные методы исследования и прогностические факторы возникновения синдрома легочной гипертензии и выживаемости. Выявлены основные факторы возникновения застойной сердечной недостаточности и риска внезапной смерти.

Relevance

Relevance. The paper presents a scientifically based approach to the diagnosis of arrhythmogenic dysplasia of the right ventricle in dogs of the Boxer, English Bulldog and mestizos breeds of these breeds. The relevance of the study is determined by the increased frequency of the disease, which is later (with untimely diagnosis) the cause of the development of pulmonary hypertension.

Methods and materials

Methods and materials. A comprehensive methodological approach was used, including a superficial clinical examination, examination of the area of the pathological process using visual diagnostics and electrocardiography. The studies were conducted on clinical material from 25 sick dogs aged 5–7 years of the Boxer, English Bulldog and Mestizo breeds with symptoms of shortness of breath, lethargy and loss of consciousness. A comprehensive diagnostic approach was used, including echocardiographic examination and electrocardiography.

Results

Results. Based on the data obtained, depending on the severity of the animal’s condition, the most accurate research methods and prognostic factors for the occurrence of pulmonary hypertension syndrome and survival were determined. The main factors of congestive heart failure and the risk of sudden death have been identified.

аритмогенная дисплазиясобакиэхокардиографияэлектрокардиографиялегочная гипертензияarrhythmogenic dysplasiadogsechocardiographyelectrocardiographypulmonary hypertensionReferencesHarpster N.K. Boxer Cardiomyopathy: A Review of the Long-Term Benefits of Antiarrhythmic Therapy. Veterinary Clinics of North America:.Small.Animal.Practice. 1991; 21(5): 989‒1004. https://doi.org/10.1016/s0195-5616(91)50107-8Harpster N.K. Boxer Cardiomyopathy: A Review of the Long-Term Benefits of Antiarrhythmic Therapy. Veterinary Clinics of North America:.Small.Animal.Practice. 1991; 21(5): 989‒1004. https://doi.org/10.1016/s0195-5616(91)50107-8Holdt S.L., Peckens N.K., Rosenthal S., Cober R. Arrhythmogenic right ventricular cardiomyopathy in Bulldogs: Evaluation of clinical and histopathologic features, progression, and outcome in 71 dogs (2004–2016). Journal of Veterinary Cardiology. 2022; 40: 170‒183. https://doi.org/10.1016/j.jvc.2021.10.003Holdt S.L., Peckens N.K., Rosenthal S., Cober R. Arrhythmogenic right ventricular cardiomyopathy in Bulldogs: Evaluation of clinical and histopathologic features, progression, and outcome in 71 dogs (2004–2016). Journal of Veterinary Cardiology. 2022; 40: 170‒183. https://doi.org/10.1016/j.jvc.2021.10.003Cunningham S.M., Dos Santos L. Arrhythmogenic right ventricular cardiomyopathy in dogs. Journal of Veterinary Cardiology. 2022; 40: 156‒169. https://doi.org/10.1016/j.jvc.2021.07.001Cunningham S.M., Dos Santos L. Arrhythmogenic right ventricular cardiomyopathy in dogs. Journal of Veterinary Cardiology. 2022; 40: 156‒169. https://doi.org/10.1016/j.jvc.2021.07.001Cunningham S.M., Sweeney J.T., MacGregor J., Barton B.A., Rush J.E. Clinical Features of English Bulldogs with Presumed Arrhythmogenic Right Ventricular Cardiomyopathy: 31 Cases (2001–2013). Journal of the American Animal Hospital Association. 2018; 54(2): 95‒102. https://doi.org/10.5326/JAAHA-MS-6550Cunningham S.M., Sweeney J.T., MacGregor J., Barton B.A., Rush J.E. Clinical Features of English Bulldogs with Presumed Arrhythmogenic Right Ventricular Cardiomyopathy: 31 Cases (2001–2013). Journal of the American Animal Hospital Association. 2018; 54(2): 95‒102. https://doi.org/10.5326/JAAHA-MS-6550Palermo V., Stafford Johnson M.J., Sala E., Brambilla P.G., Martin M.W.S. Cardiomyopathy in Boxer dogs: A retrospective study of the clinical presentation, diagnostic findings and survival. Journal of Veterinary Cardiology. 2011; 13(1): 45‒55. https://doi.org/10.1016/j.jvc.2010.06.005Palermo V., Stafford Johnson M.J., Sala E., Brambilla P.G., Martin M.W.S. Cardiomyopathy in Boxer dogs: A retrospective study of the clinical presentation, diagnostic findings and survival. Journal of Veterinary Cardiology. 2011; 13(1): 45‒55. https://doi.org/10.1016/j.jvc.2010.06.005Wess G. Screening for dilated cardiomyopathy in dogs. Journal of Veterinary Cardiology. 2022; 40: 51‒68. https://doi.org/10.1016/j.jvc.2021.09.004Wess G. Screening for dilated cardiomyopathy in dogs. Journal of Veterinary Cardiology. 2022; 40: 51‒68. https://doi.org/10.1016/j.jvc.2021.09.004Vila J. et.al. Structural and molecular pathology of the atrium in boxer arrhythmogenic right ventricular cardiomyopathy. Journal of Veterinary Cardiology. 2017; 19(1): 57‒67. https://doi.org/10.1016/j.jvc.2016.09.001Vila J. et.al. Structural and molecular pathology of the atrium in boxer arrhythmogenic right ventricular cardiomyopathy. Journal of Veterinary Cardiology. 2017; 19(1): 57‒67. https://doi.org/10.1016/j.jvc.2016.09.001Kiès P., Bootsma M., Bax J., Schalij M.J., van der Wall E.E. Arrhythmogenic right ventricular dysplasia/cardiomyopathy: screening, diagnosis, and treatment. Heart Rhythm. 2006; 3(2): 225‒234. https://doi.org/10.1016/j.hrthm.2005.10.018Kiès P., Bootsma M., Bax J., Schalij M.J., van der Wall E.E. Arrhythmogenic right ventricular dysplasia/cardiomyopathy: screening, diagnosis, and treatment. Heart Rhythm. 2006; 3(2): 225‒234. https://doi.org/10.1016/j.hrthm.2005.10.018Meurs K.M. Boxer dog cardiomyopathy: an update. Veterinary Clinics of North America: Small Animal Practice. 2004; 34(5): 1235‒1244. https://doi.org/10.1016/j.cvsm.2004.05.003Meurs K.M. Boxer dog cardiomyopathy: an update. Veterinary Clinics of North America: Small Animal Practice. 2004; 34(5): 1235‒1244. https://doi.org/10.1016/j.cvsm.2004.05.003Oxford E.M. et.al. Ultrastructural changes in cardiac myocytes from Boxer dogs with arrhythmogenic right ventricular cardiomyopathy. Journal of Veterinary Cardiology. 2011; 13(2): 101‒113. https://doi.org/10.1016/j.jvc.2011.03.002Oxford E.M. et.al. Ultrastructural changes in cardiac myocytes from Boxer dogs with arrhythmogenic right ventricular cardiomyopathy. Journal of Veterinary Cardiology. 2011; 13(2): 101‒113. https://doi.org/10.1016/j.jvc.2011.03.002Potter B.M., Scansen B.A., Chi I.B., Gagnon A.L., Orton E.C. Trifoliate left atrioventricular valve with and without intact septal structures in four dogs: echocardiographic findings and surgical repair. Journal of Veterinary Cardiology. 2022; 41: 70‒78. https://doi.org/10.1016/j.jvc.2022.01.009Potter B.M., Scansen B.A., Chi I.B., Gagnon A.L., Orton E.C. Trifoliate left atrioventricular valve with and without intact septal structures in four dogs: echocardiographic findings and surgical repair. Journal of Veterinary Cardiology. 2022; 41: 70‒78. https://doi.org/10.1016/j.jvc.2022.01.009Vila B.C.P., Camacho A.A., Sousa M.G. T-wave peak-end interval and ratio of T-wave peak-end and QT intervals: novel arrhythmogenic and survival markers for dogs with myxomatous mitral valve disease. Journal of Veterinary Cardiology. 2021; 35: 25‒41. https://doi.org/10.1016/j.jvc.2021.02.004Vila B.C.P., Camacho A.A., Sousa M.G. T-wave peak-end interval and ratio of T-wave peak-end and QT intervals: novel arrhythmogenic and survival markers for dogs with myxomatous mitral valve disease. Journal of Veterinary Cardiology. 2021; 35: 25‒41. https://doi.org/10.1016/j.jvc.2021.02.004Keene B.W. et.al. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. Journal of Veterinary Internal Medicine.2019; 33(3): 1127‒1140. https://doi.org/10.1111/jvim.15488Keene B.W. et.al. ACVIM consensus guidelines for the diagnosis and treatment of myxomatous mitral valve disease in dogs. Journal of Veterinary Internal Medicine.2019; 33(3): 1127‒1140. https://doi.org/10.1111/jvim.15488Kong P.K., Lam E.M., Sheikh Abdul Kader M.A. Systolic pulmonary artery pressure derived from pulmonary artery acceleration time could cross-check with pressure derived from simplified Bernoulli Eq. International Journal of Cardiology. 2021; 345(S): 42‒43. https://doi.org/10.1016/j.ijcard.2021.10.123Kong P.K., Lam E.M., Sheikh Abdul Kader M.A. Systolic pulmonary artery pressure derived from pulmonary artery acceleration time could cross-check with pressure derived from simplified Bernoulli Eq. International Journal of Cardiology. 2021; 345(S): 42‒43. https://doi.org/10.1016/j.ijcard.2021.10.123Khan Z., Abumedian M., Yousif Y., Gupta A., Myo S.L., Mlawa G. Arrhythmogenic Right Ventricular Cardiomyopathy in a Patient Experiencing Out-of-Hospital Ventricular Fibrillation Arrest Twice: Case Report and Review of the Literature Cureus. 2022; 14(1): e21457. https://doi.org/10.7759/cureus.21457Khan Z., Abumedian M., Yousif Y., Gupta A., Myo S.L., Mlawa G. Arrhythmogenic Right Ventricular Cardiomyopathy in a Patient Experiencing Out-of-Hospital Ventricular Fibrillation Arrest Twice: Case Report and Review of the Literature Cureus. 2022; 14(1): e21457. https://doi.org/10.7759/cureus.21457

The authors declare that there are no conflicts of interest present.