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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vetpress</journal-id><journal-title-group><journal-title xml:lang="ru">Аграрная наука</journal-title><trans-title-group xml:lang="en"><trans-title>Agrarian science</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-8155</issn><issn pub-type="epub">2686-701X</issn><publisher><publisher-name>Редакция журнала "Аграрная наука"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.32634/0869-8155-2025-400-11-167-186</article-id><article-id custom-type="elpub" pub-id-type="custom">vetpress-3904</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АГРОИНЖЕНЕРИЯ И ПИЩЕВЫЕ ТЕХНОЛОГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>AGROENGINEERING AND FOOD TECHNOLOGIES</subject></subj-group></article-categories><title-group><article-title>Методы определения полициклических ароматических углеводородов в молоке и молочных продуктах</article-title><trans-title-group xml:lang="en"><trans-title>Methods for determination of polycyclic aromatic hydrocarbons in milk and dairy products</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4753-3210</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lukin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Александр Анатольевич Лукин, кандидат технических наук, доцент </p><p> ул. им. Гагарина, 13, Троицк, 457100 </p><p> пр-т им. Ленина, 76, Челябинск, 454080 </p></bio><bio xml:lang="en"><p> Aleksandеr Anatolyevich Lukin, Candidate of Technical Sciences, Associate Professor </p><p> 13 Gagarin Str., Troitsk, 457100</p><p> 76 Lenin Аve., Chelyabinsk, 454080 </p></bio><email xlink:type="simple">lukin3415@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1179-4227</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кан</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Can</surname><given-names>Ö. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Озлем Пелин Кан, доктор философских наук, профессор кафедры гигиены и технологии пищевых продуктов факультета ветеринарной медицины </p><p> Кампус университета, Сивас, 58140 </p></bio><bio xml:lang="en"><p> Özlem Pelin Can, Doctor of Philosophy, Professor, Department of Hygiene and Food Technology, Faculty of Veterinary Medicine </p><p> Campus Central Sivas, Sivas, 58140 </p></bio><email xlink:type="simple">opcan@cumhuriyet.edu.tr</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Южно-Уральский государственный аграрный университет; Южно-Уральский государственный университет (национальный исследовательский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>South Ural State Agrarian University; South Ural State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Университет Сивас Джумхуриет</institution><country>Турция</country></aff><aff xml:lang="en"><institution>Sivas Cumhuriyet University</institution><country>Turkey</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>19</day><month>11</month><year>2025</year></pub-date><volume>0</volume><issue>11</issue><fpage>167</fpage><lpage>186</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лукин А.А., Кан О.П., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Лукин А.А., Кан О.П.</copyright-holder><copyright-holder xml:lang="en">Lukin A.A., Can Ö.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vetpress.ru/jour/article/view/3904">https://www.vetpress.ru/jour/article/view/3904</self-uri><abstract><p>Научный обзор посвящен методам определения полициклических ароматических углеводородов (ПАУ) в молоке и молочных продуктах. Основное внимание уделено точности, надежности и доступности используемых методик, обеспечивающих контроль качества пищевых продуктов. Рассматриваются разнообразные техники анализа, включая жидкостную и газовую хроматографию, спектроскопию и микрофлуоресценцию. Отмечается, что существующие технологии обеспечивают достаточную точность и воспроизводимость результатов, способствуя повышению безопасности молочных продуктов. Несмотря на сложность процедур, современная техника обеспечивает надежные результаты и способствует контролю качества продуктов питания. ПАУ классифицируются по молекулярной массе и происхождению, различаются по уровню токсичности и способности накапливаться в живых организмах. Подробно рассматриваются методы экстракции и очистки, включая жидкостную и газовую хроматографию, рамановскую микроскопию и инфракрасную спектроскопию. Приводятся международные рекомендации и ограничения на содержание ПАУ в пищевых продуктах, установленные Агентством по охране окружающей среды США и Европейским агентством по безопасности пищевых продуктов. Оцениваются перспективы использования различных методов анализа в реальных условиях, подчеркивая важность точного контроля содержания ПАУ в молочных продуктах. Научный обзор подчеркивает необходимость дальнейшего совершенствования методов анализа и контроля ПАУ, а также важность сотрудничества между молочной промышленностью и профессиональными лабораториями для минимизации риска загрязнений.</p></abstract><trans-abstract xml:lang="en"><p>This scientific review is dedicated to analytical methods for the determination of polycyclic aromatic hydrocarbons (PAHs) in milk and dairy products. The primary focus is placed on the accuracy, reliability, and accessibility of the methodologies employed for food quality control. A comprehensive examination of various analytical techniques is provided, including liquid and gas chromatography, spectroscopy, and micro-fluorescence. It is noted that existing technologies ensure sufficient accuracy and reproducibility of results, thereby enhancing the safety of dairy products. Despite the complexity of the procedures, modern instrumentation delivers reliable outcomes and supports effective food quality control. PAHs are classified based on their molecular weight and origin, differing in their toxicity levels and capacity for bioaccumulation in living organisms. The review offers a detailed assessment of extraction and purification methods, encompassing liquid and gas chromatography, Raman microscopy, and infrared spectroscopy. International guidelines and regulatory limits for PAH content in foodstuffs, as established by the US Environmental Protection Agency (EPA) and the European Food Safety Authority (EFSA), are presented. The prospects for the application of various analytical methods in real-world settings are evaluated, emphasizing the critical importance of precise monitoring of PAH levels in dairy products. This review underscores the necessity for the continued refinement of PAH analysis and control methods, as well as the significance of collaboration between the dairy industry and specialized laboratories to minimize contamination risks.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>молоко</kwd><kwd>молочные продукты</kwd><kwd>полициклические ароматические углеводороды</kwd><kwd>окружающая среда</kwd><kwd>загрязнители</kwd><kwd>безопасность</kwd><kwd>токсичность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>milk</kwd><kwd>dairy products</kwd><kwd>polycyclic aromatic hydrocarbons</kwd><kwd>environment</kwd><kwd>pollutants</kwd><kwd>safety</kwd><kwd>toxicity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rebezov M.B., Temerbaeva M.V., Uryumtseva T.I. Results of mathematical analysis of experimental data fermentation of skimmed milk to produce a fermented milk product. Bulletin of the Innovative University of Eurasia. 2022; (3): 65–71. https://www.elibrary.ru/wonjpw</mixed-citation><mixed-citation xml:lang="en">Rebezov M.B., Temerbaeva M.V., Uryumtseva T.I. Results of mathematical analysis of experimental data fermentation of skimmed milk to produce a fermented milk product. Bulletin of the Innovative University of Eurasia. 2022; (3): 65–71. https://www.elibrary.ru/wonjpw</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Serikova A. et al. Development of Technology of Fermented Milk Drink With Immune Stimulating Properties. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2018; 9(4): 495–500. https://www.elibrary.ru/xrwrfr</mixed-citation><mixed-citation xml:lang="en">Serikova A. et al. Development of Technology of Fermented Milk Drink With Immune Stimulating Properties. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2018; 9(4): 495–500. https://www.elibrary.ru/xrwrfr</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Итбалакова А.Б., Мухтарханова Р.Б., Матибаева А.И., Ребезов М.Б. Разработка технологии нового кисломолочного продукта с использованием микробиологического консорциума (патентный поиск). Научно-практическое развитие АПК и производства продуктов здорового питания. Материалы Международной научно-практической конференции, посвященной юбилею заслуженного работника высшей школы Российской Федерации доктора технических наук, профессора Н.Б. Гавриловой. Омск: Омский государственный аграрный университет. 2025; 38–42. https://www.elibrary.ru/lryjwd</mixed-citation><mixed-citation xml:lang="en">Itbalakova A.B., Mukhtarkhanova R.B., Matibayeva A.I., Rebezov M.B. Development of a new fermented milk product technology using a microbiological consortium (patent search). Scientific and practical development of the agro-industrial complex and the production of healthy food products. Proceedings of the International scientific and practical conference dedicated to the anniversary of Honored Worker of Higher Education of the Russian Federation Doctor of Engineering, Professor N.B. Gavrilova. Omsk: Omsk State Agrarian University. 2025; 38–42 (in Russian). https://www.elibrary.ru/lryjwd</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Темербаева М.В., Гаврилова Н.Б., Ребезов М.Б. Разработка биотехнологии молочного продукта для питания диабетиков. Современное состояние, перспективы развития АПК и производства специализированных продуктов питания. Материалы Международной научно-практической конференции посвященной юбилею заслуженного работника высшей школы Российской Федерации доктора технических наук, профессора Н.Б. Гавриловой. Омск: Омский государственный аграрный университет. 2020; 520–527. https://www.elibrary.ru/ndipln</mixed-citation><mixed-citation xml:lang="en">Temerbaeva M.V., Gavrilova N.B., Rebezov M.B. Development of biotechnology of dairy product for nutrition of diabetics. Current state and prospects for development of the agro-industrial complex and production of specialized food products. Proceedings of the International scientific and practical conference dedicated to the anniversary of Honored Worker of Higher Education of the Russian Federation Doctor of Engineering, Professor N.B. Gavrilova. Omsk: Omsk State Agrarian University. 2020; 520–527 (In Russian). https://www.elibrary.ru/ndipln</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Павлова Я.С., Харина П.Д. Полезные свойства коровьего молока. Приоритетные направления развития аграрной науки и технологий. Сборник тезисов научно-практической конференции, посвященной 75-летнему юбилею факультета биотехнологии и пищевой инженерии. Екатеринбург: Уральский государственный аграрный университет. 2024; 2: 589–591. https://www.elibrary.ru/rmjupe</mixed-citation><mixed-citation xml:lang="en">Pavlova Ya.S., Kharina P.D. Useful properties of cow’s milk. Priority directions for the development of agricultural science and technology. Collection of abstracts of the scientific and practical conference dedicated to the 75th anniversary of the Faculty of Biotechnology and Food Engineering. Yekaterinburg: Ural State Agrarian University. 2024; 2: 589–591 (In Russian). https://www.elibrary.ru/rmjupe</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Smolnikova F. et al. Developing milk-fruit drinks for school nutrition. Journal of Natural Remedies. 2021; 21(9-1): 72–77. https://www.elibrary.ru/fwcshs</mixed-citation><mixed-citation xml:lang="en">Smolnikova F. et al. Developing milk-fruit drinks for school nutrition. Journal of Natural Remedies. 2021; 21(9-1): 72–77. https://www.elibrary.ru/fwcshs</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Белооков А.А., Белоокова О.В., Горелик О.В., Ребезов М.Б. Состав и свойства молока коров черно-пестрой породы разных генотипов. Аграрная наука. 2023; (3): 62–69. https://doi.org/10.32634/0869-8155-2023-368-3-62-69</mixed-citation><mixed-citation xml:lang="en">Belookov A.A., Belookova O.V., Gorelik O.V., Rebezov M.B. The composition and properties of the milk of black-and-white cows of different genotypes. Agrarian science. 2023; (3): 62–69 (In Russian). https://doi.org/10.32634/0869-8155-2023-368-3-62-69</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Temerbaeva M. et al. Technology of Sour Milk Product For Elderly Nutrition. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2018; 9(1): 291–295. https://www.elibrary.ru/xnjgkt</mixed-citation><mixed-citation xml:lang="en">Temerbayeva M. et al. Technology of Sour Milk Product For Elderly Nutrition. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2018; 9(1): 291–295. https://www.elibrary.ru/xnjgkt</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Иванникова Е.В., Дудинская Е.Н., Ткачева О.Н. Вопросы питания и нутритивной поддержки при остеопорозе. Российский журнал гериатрической медицины. 2023; (2): 92–104. https://doi.org/10.37586/2686-8636-2-2023-92-104</mixed-citation><mixed-citation xml:lang="en">Ivannikova E.V., Dudinskaya E.N., Tkacheva O.N. Nutrients and Dietary Patterns for Osteoporosis. Russian Journal of Geriatric Medicine. 2023; (2): 92–104 (In Russian). https://doi.org/10.37586/2686-8636-2-2023-92-104</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Епураш С.Д. Молочные белки. Польза молочных продуктов. Кузбасс: образование, наука, инновации. Материалы XII Инновационного конвента. Кемерово: Кемеровский государственный университет. 2024; 199–200. https://www.elibrary.ru/axolun</mixed-citation><mixed-citation xml:lang="en">Epurash S.D. Milk proteins. The benefits of dairy products. Kuzbass: education, science, innovation. Proceedings of the XII Innovation Convention. Kemerovo: Kemerovo State University. 2024; 199–200 (In Russian). https://www.elibrary.ru/axolun</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Смольникова Ф.Х., Наурзбаева Г.К., Асенова Б.К., Ребезов М.Б. Использование вторичных молочных продуктов пахты и сыворотки. Развитие биотехнологии: новая реальность. Сборник Международной научно-практической конференции, приуроченной к 100-летнему юбилею почетного ректора НГАУ профессора, доктора сельскохозяйственных наук И.И. Гудилина. Новосибирск: Золотой колос. 2022; 154–159. https://www.elibrary.ru/fdixfh</mixed-citation><mixed-citation xml:lang="en">Smolnikova F.Kh., Naurzbaeva G.K., Asenova B.K., Rebezov M.B. Use of secondary dairy products buttermium and wHEY. Biotechnology development: a new reality. Proceedings of the International scientific and practical conference dedicated to the 100th anniversary of the Honorary Rector of NSAU, Professor Doctor of Agricultural Sciences I.I. Gudilin. Novosibirsk: Zolotoy kolos. 2022; 154–159 (In Russian). https://www.elibrary.ru/fdixfh</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Temerbaeva M. et al. Using of Creamy Bioadditives in the Production of Melted Cheese. International Journal of Engineering and Technology. 2018; 7(4.38): 1240–1242. https://doi.org/10.14419/ijet.v7i4.38.27796</mixed-citation><mixed-citation xml:lang="en">Temerbaeva M. et al. Using of Creamy Bioadditives in the Production of Melted Cheese. International Journal of Engineering and Technology. 2018; 7(4.38): 1240–1242. https://doi.org/10.14419/ijet.v7i4.38.27796</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Нарузбаева Г.К., Смольникова Ф.Х., Ребезов М.Б. Совершенствование технологии сливочного масла. Наука, образование и инновации для АПК: состояние, проблемы и перспективы. Материалы VI Международной научно-практической онлайн-конференции. Майкоп: Магарин О.Г. 2020; 513–515. https://www.elibrary.ru/ulejxf</mixed-citation><mixed-citation xml:lang="en">Naruzbayeva G.K., Smolnikova F.Kh., Rebezov M.B. Improving butter technology. Science, education and innovation for the agroindustrial complex: status, problems and prospects. Proceedings of the VI International scientific and practical online conference. Maykop: Magarin O.G. 2020; 513–515 (In Russian). https://www.elibrary.ru/ulejxf</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Смольникова Ф.Х. Наурзбаева Г.К., Ребезов М.Б., Окусханова Э.К., Кулуштаева Б.М. Исследование пищевой безопасности сливочного масла с растительными компонентами. Вестник Университета Шакарима. Серия: Технические науки. 2024; (4): 190–199. https://doi.org/10.53360/2788-7995-2024-4(16)-25</mixed-citation><mixed-citation xml:lang="en">Smolnikova F.H., Naurzbaeva G.K., Rebezov M.B., Okuskhanova E.K., Kulushtaeva B.M. Investigation of the food safety of butter with vegetable components. Bulletin of Shakarim University. Series: Technical Sciences. 2024; (4): 190–199 (In Russian). https://doi.org/10.53360/2788-7995-2024-4(16)-25</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Расулов У.И., Боймуратова Х.Ш., Солиева И. Молоко — продукт с высокой пищевой ценностью (анализ литературных данных). Молодые ученые — науке и практике АПК. Материалы Международной научно-практической конференции аспирантов и молодых ученых. Витебск: Витебская государственная академия ветеринарной медицины. 2024; 385–388. https://www.elibrary.ru/hrjvaa</mixed-citation><mixed-citation xml:lang="en">Rasulov U.I., Boymuratova Kh.Sh., Solieva I. Milk is a product with high nutritional value (analysis of literary data). Young scientists — for science and practice of the agro-industrial complex. Proceedings of the International scientific and practical conference of postgraduate students and young scientists. Vitebsk: Vitebsk State Academy of Veterinary Medicine. 2024; 385–388 (In Russian). https://www.elibrary.ru/hrjvaa</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Зобнина И.Н., Чепуштанова О.В. Физико-химические показатели овечьего молока. Современные технологии птицеводства и мелкого животноводства. Сборник материалов круглого стола. Екатеринбург: Уральский государственный аграрный университет. 2023; 1: 191–192. https://www.elibrary.ru/wsucpq</mixed-citation><mixed-citation xml:lang="en">Zobnina I.N., Chepushtanova O.V. Physicochemical parameters of sheep milk. Modern technologies of poultry farming and smallscale livestock farming. Collection of materials from a round table. Yekaterinburg: Ural State Agrarian University. 2023; 1: 191–192 (In Russian). https://www.elibrary.ru/wsucpq</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Temerbaeva M. et al. Development of Yoghurt from Combination of Goat and Cow Milk. Annual Research &amp; Review in Biology. 2018; 23(6): 38800. https://doi.org/10.9734/ARRB/2018/38800</mixed-citation><mixed-citation xml:lang="en">Temerbaeva M. et al. Development of Yoghurt from Combination of Goat and Cow Milk. Annual Research &amp; Review in Biology. 2018; 23(6): 38800. https://doi.org/10.9734/ARRB/2018/38800</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Темербаева М.В., Бестиева М.С., Урюмцева Т.И., Ребезов М.Б. Разработка технологии фруктовых десертов с бифидогенными свойствами на основе козьего молока. Вестник Алматинского технологического университета. 2019; (3): 56–59. https://www.elibrary.ru/rchhlw</mixed-citation><mixed-citation xml:lang="en">Temerbaeva M.V., Bestieva M.S., Uryumtseva T.I., Rebezov M.B. Development of fruit dessert technology with bifidogenic properties based on goat’s milk. The Journal of Almaty Technological University. 2019; (3): 56–59 (In Russian). https://www.elibrary.ru/rchhlw</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Темербаева М.В., Бестиева М.С., Урюмцева Т.И., Ребезов М.Б. Методология проведения исследований при разработке десертов на основе козьего молока. Вестник Алматинского технологического университета. 2019; (4): 16–19. https://www.elibrary.ru/anscah</mixed-citation><mixed-citation xml:lang="en">Temerbaeva M.V., Bestieva M.S., Uryumtceva T.I., Rebezov M.B. Research methodology in the development of desserts based on goat milk. The Journal of Almaty Technological University. 2019; (4): 16–19 (In Russian). https://www.elibrary.ru/anscah</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Темербаева М.В., Ребезов М.Б. Разработка технологии кисломолочного продукта на основе козьего молока для питания беременных и кормящих женщин. Научные инновации — аграрному производству. Материалы Международной научнопрактической конференции, посвященной 100-летнему юбилею Омского ГАУ. Омск: Омский государственный аграрный университет. 2018; 1436–1440. https://www.elibrary.ru/xmoqlz</mixed-citation><mixed-citation xml:lang="en">Temerbaeva M.V., Rebezov M.B. Development of technology of fermented milk product based on goat milk for nutrition pregnant and lactating women. Scientific innovations for agricultural production. Proceedings of the International scientific and practical conference dedicated to the 100th anniversary of Omsk State Agrarian University. Omsk: Omsk State Agrarian University. 2018; 1436–1440 (In Russian). https://www.elibrary.ru/xmoqlz</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Горелик А.С., Горелик О.В., Ребезов М.Б., Харлап С.Ю. Динамика молочной продуктивности коров голштинской породы в зависимости от возраста в лактациях. Вестник Ошского государственного университета. Сельское хозяйство: агрономия, ветеринария и зоотехния. 2025; (1): 146–157. https://www.elibrary.ru/wmyenz</mixed-citation><mixed-citation xml:lang="en">Gorelik A.S., Gorelik O.V., Rebezov M.B., Kharlap S.Yu. Dynamics of milk productivity of Holstein cows depending on age in lactations. Journal of Osh State University. Agriculture: Agronomy, Veterinary and Zootechnics. 2025; (1): 146–157 (In Russian). https://www.elibrary.ru/wmyenz</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Ребезов М.Б., Наумова Н.Л., Альхамова Г.К., Кожевникова Е.Ю., Сорокин А.В. Конъюнктура предложения обогащенных молочных продуктов на примере Челябинска. Молочная промышленность. 2011; (8): 38–39. https://www.elibrary.ru/nygqsr</mixed-citation><mixed-citation xml:lang="en">Rebezov M.B., Naumova N.L., Alhamova G.K., Kozhevnikova E.Yu., Sorokin A.V. Offers of the enriched milk products in Chelyabinsk. Dairy industry. 2011; (8): 38–39 (In Russian). https://www.elibrary.ru/nygqsr</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Қалибекқызы Ж., Жакупбекова Ш.К., Ребезов М.Б., Смольникова Ф.Х., Майжанова А.О. Исследование качественных характеристик, показателей пищевой безопасности цельного молока, используемого для производства курта. Вестник Университета Шакарима. Серия: Технические науки. 2025; (1): 312–321. https://doi.org/10.1016/10.53360/2788-7995-2025-1(17)-40</mixed-citation><mixed-citation xml:lang="en">Kalibekkyzy Zh., Zhakupbekova Sh.K., Rebezov M.B., Smolnikova F.H., Maizhanova A.O. Research of qualitative characteristics, indicators of food safety of whole milk used for the production of kurt. Bulletin of Shakarim University. Series: Technical Sciences. 2025; (1): 312–321 (In Russian). https://doi.org/10.53360/2788-7995-2025-1(17)-40</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Gavrilova N. et al. Development of specialized food products for nutrition of sportsmen. Journal of Critical Reviews. 2020; 7(4): 233–236. https://www.elibrary.ru/rhzgio</mixed-citation><mixed-citation xml:lang="en">Gavrilova N. et al. Development of specialized food products for nutrition of sportsmen. Journal of Critical Reviews. 2020; 7(4): 233–236. https://www.elibrary.ru/rhzgio</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Gavrilova N. et al. Advanced Biotechnology of Specialized Fermented Milk Products. International Journal of Recent Technology and Engineering. 2019; 8(2): 2718–2722. https://doi.org/10.35940/ijrte.B3158.078219</mixed-citation><mixed-citation xml:lang="en">Gavrilova N. et al. Advanced Biotechnology of Specialized Fermented Milk Products. International Journal of Recent Technology and Engineering. 2019; 8(2): 2718–2722. https://doi.org/10.35940/ijrte.B3158.078219</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Gavrilova N. et al. Biotechnology application in production of specialized dairy products using probiotic cultures immobilization. International Journal of Innovative Technology and Exploring Engineering. 2019; 8(6): 642–648. https://www.elibrary.ru/pydnoh</mixed-citation><mixed-citation xml:lang="en">Gavrilova N. et al. Biotechnology application in production of specialized dairy products using probiotic cultures immobilization. International Journal of Innovative Technology and Exploring Engineering. 2019; 8(6): 642–648. https://www.elibrary.ru/pydnoh</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Chernopolskaya N. et al. Biotechnology of specialized fermented product for elderly nutrition. International Journal of Pharmaceutical Research. 2019; 11(1): 545–550. https://www.elibrary.ru/jqfiot</mixed-citation><mixed-citation xml:lang="en">Chernopolskaya N. et al. Biotechnology of specialized fermented product for elderly nutrition. International Journal of Pharmaceutical Research. 2019; 11(1): 545–550. https://www.elibrary.ru/jqfiot</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Chernopolskaya N. et al. Biotechnology of specialized product for sports nutrition. International Journal of Engineering and Advanced Technology. 2019; 8(4): 40–45. https://www.elibrary.ru/strlxl</mixed-citation><mixed-citation xml:lang="en">Chernopolskaya N. et al. Biotechnology of specialized product for sports nutrition. International Journal of Engineering and Advanced Technology. 2019; 8(4): 40–45. https://www.elibrary.ru/strlxl</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Сапожникова О.О., Улыбина Л.В. Конъюнктура мирового рынка молочной продукции. Молодежь и инновации. Материалы XXI Всероссийской (национальной) научно-практической конференции молодых ученых, аспирантов и студентов. Чебоксары: Чувашский государственный аграрный университет. 2025; 445–447. https://www.elibrary.ru/jsvarb</mixed-citation><mixed-citation xml:lang="en">Sapozhnikova O.O., Ulybina L.V. World dairy products market conjuncture. Youth and Innovation. Proceedings of the XXI All-Russian (national) scientific and practical conference of young scientists, postgraduates, and students. Cheboksary: Chuvash State Agrarian University. 2025; 445–447 (In Russian). https://www.elibrary.ru/jsvarb</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Pereira P.C. Milk nutritional composition and its role in human health. Nutrition. 2014; 30(6): 619–627. https://doi.org/10.1016/J.NUT.2013.10.011</mixed-citation><mixed-citation xml:lang="en">Pereira P.C. Milk nutritional composition and its role in human health. Nutrition. 2014; 30(6): 619–627. https://doi.org/10.1016/J.NUT.2013.10.011</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Опополь Н.И., Сырку Р.Ф., Пынзару Ю.В., Богдевич О.П., Кадочников О.П. Гигиеническая оценка содержания полициклических ароматических углеводородов в продуктах питания и их поступления в организм населения. Гигиена и санитария. 2015; 94(4): 52–56. https://www.elibrary.ru/uhkwbj</mixed-citation><mixed-citation xml:lang="en">Opopol N.I., Syrku R.F., Pynzaru Yu.V., Bogdevich O.P., Kadochnikov O.P. Hygienic assessment of polycyclic aromatic hydrocarbons content and estimation of their intake with food by the population. Hygiene and Sanitation. 2015; 94(4): 52–56 (In Russian). https://www.elibrary.ru/uhkwbj</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Фрумин Г.Т. Прогресс химии и экологии. Часть II. Полициклические ароматические углеводороды и другие загрязняющие вещества. Экологическая химия. 2024; 33(5): 233–240. https://www.elibrary.ru/rjhjae</mixed-citation><mixed-citation xml:lang="en">Frumin G.T. Progress of chemistry and ecology. Part II. Polycyclic aromatic hydrocarbons and other pollutants. Ekologicheskaya khimiya. 2024; 33(5): 233–240 (In Russian). https://www.elibrary.ru/rjhjae</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Cuesta-Triana F., Verdejo-Bravo C., Fernández-Pérez C., Martín-Sánchez F.J. Effect of Milk and Other Dairy Products on the Risk of Frailty, Sarcopenia, and Cognitive Performance Decline in the Elderly: A Systematic Review. Advances in Nutrition. 2019; 10(S2): S105–S119. https://doi.org/10.1093/advances/nmy105</mixed-citation><mixed-citation xml:lang="en">Cuesta-Triana F., Verdejo-Bravo C., Fernández-Pérez C., Martín-Sánchez F.J. Effect of Milk and Other Dairy Products on the Risk of Frailty, Sarcopenia, and Cognitive Performance Decline in the Elderly: A Systematic Review. Advances in Nutrition. 2019; 10(S2): S105–S119. https://doi.org/10.1093/advances/nmy105</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Zanini B., Simonetto A., Zubani M., Castellano M., Gilioli G. The Effects of Cow-Milk Protein Supplementation in Elderly Population: Systematic Review and Narrative Synthesis. Nutrients. 2020; 12(9): 2548. https://doi.org/10.3390/nu12092548</mixed-citation><mixed-citation xml:lang="en">Zanini B., Simonetto A., Zubani M., Castellano M., Gilioli G. The Effects of Cow-Milk Protein Supplementation in Elderly Population: Systematic Review and Narrative Synthesis. Nutrients. 2020; 12(9): 2548. https://doi.org/10.3390/nu12092548</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Kuramshina N. et al. Heavy metals content in meat and milk of Orenburg region of Russia. International Journal of Pharmaceutical Research. 2019; 11(1): 1031–1035. https://www.elibrary.ru/zsxhdf</mixed-citation><mixed-citation xml:lang="en">Kuramshina N. et al. Heavy metals content in meat and milk of Orenburg region of Russia. International Journal of Pharmaceutical Research. 2019; 11(1): 1031–1035. https://www.elibrary.ru/zsxhdf</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Лаврушина Е.Е., Ребезов М.Б., Топурия Г.М., Топурия Л.Ю., Ступина М.Ю. Гигиеническая оценка молока коз по содержанию радионуклидов. Актуальные проблемы интенсивного развития животноводства. Сборник научных трудов Международной научно-практической конференции, посвященный памяти заслуженного работника Высшей школы РФ, почетного работника высшего профессионального образования РФ, почетного профессора Брянской ГСХА, почетного гражданина Брянской области доктора биологических наук, профессора Е.П. Ващекина. Брянск: Брянский государственный аграрный университет. 2025; 115–119. https://www.elibrary.ru/bliide</mixed-citation><mixed-citation xml:lang="en">Lavrushina E.E., Rebezov M.B., Topuria G.M., Topuria L.Yu., Stupina M.Yu. Hygienic evaluation of goat milk by radionuclide content. Actual problems of intensive development of animal husbandry. Collection of scientific papers of the International Scientific and Practical Conference dedicated to the memory of the Honored Worker of Higher Education of the Russian Federation, Honorary Worker of Higher Professional Education of the Russian Federation, Honorary Professor of the Bryansk State Agricultural Academy, Honorary citizen of the Bryansk region, Doctor of Biological Sciences, Professor E.P. Vashchekina. Bryansk: Bryansk State Agrarian University. 2025; 115–119 (In Russian). https://www.elibrary.ru/bliide</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Смольникова Ф.Х., Ребезов М.Б., Искакова З.И. Пищевая безопасность национальных молочных продуктов. Продовольственная безопасность и импортозамещение в условиях современного социально-экономического развития России. Материалы Международной научно-практической конференции. Коломна: Московский государственный областной социально-гуманитарный институт. 2015; 86–90. https://www.elibrary.ru/zalygd</mixed-citation><mixed-citation xml:lang="en">Smolnikova F.Kh., Rebezov M.B., Iskakova Z.I. Food safety of national dairy products. Food security and import substitution in the context of modern socio-economic development of Russia. Proceedings of the International scientific and practical conference. Kolomna: Moscow State Regional Social and Humanitarian Institute. 2015; 86–90 (In Russian). https://www.elibrary.ru/zalygd</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Суесинова Ж.А. Проблемы метрологического обеспечения качества и безопасности молока и молочной продукции. Россия — Евразия — мир: интеграция — развитие — перспектива. Материалы XIV Евразийского экономического форума молодежи. Екатеринбург: Уральский государственный экономический университет. 2024; 3: 99–101. https://www.elibrary.ru/iervkn</mixed-citation><mixed-citation xml:lang="en">Suesinova Zh.A. Problems of metrological assurance of quality and safety of milk and dairy products. Russia — Eurasia — the world: integration — development — prospect. Proceedings of the XIV Eurasian Economic Youth Forum. Yekaterinburg: Ural State University of Economics. 2024; 3: 99–101 (In Russian). https://www.elibrary.ru/iervkn</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Чупракова А.М., Ребезов М.Б. Анализ результатов проб молока и молочных продуктов, хлебобулочных и кондитерских изделий на содержание токсичных элементов. Вестник Южно-Уральского государственного университета. Серия: Пищевые и биотехнологии. 2016; 4(1): 47–54. https://doi.org/10.14529/food160106</mixed-citation><mixed-citation xml:lang="en">Chuprakova A.M., Rebezov M.B. Analysis of the results of the samples of milk and dairy products, as well as bakery and confectionery products on the content of toxic elements. Bulletin of South Ural State University. Series: Food and Biotechnology. 2016; 4(1): 47–54 (In Russian). https://doi.org/10.14529/food160106</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Ogori A.F., Girgih A.T., Abu J.O., Eke M.O. Food Derived Bioactive Peptides for Health Enhancement and Management of Some Chronic Diseases. Asian Food Science Journal. 2019; 8(1): 1–11. https://doi.org/10.9734/afsj/2019/v8i129981</mixed-citation><mixed-citation xml:lang="en">Ogori A.F., Girgih A.T., Abu J.O., Eke M.O. Food Derived Bioactive Peptides for Health Enhancement and Management of Some Chronic Diseases. Asian Food Science Journal. 2019; 8(1): 1–11. https://doi.org/10.9734/afsj/2019/v8i129981</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Żbik K., Onopiuk A., Górska-Horczyczak E., Wierzbicka A. Trends and Opportunities in the Dairy Industry: A2 Milk and Processing Methods. Applied Sciences. 2024; 14(15): 6513. https://doi.org/10.3390/app14156513</mixed-citation><mixed-citation xml:lang="en">Żbik K., Onopiuk A., Górska-Horczyczak E., Wierzbicka A. Trends and Opportunities in the Dairy Industry: A2 Milk and Processing Methods. Applied Sciences. 2024; 14(15): 6513. https://doi.org/10.3390/app14156513</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Wang C., Wang X., Yuan X., Ren J., Gong P. Organochlorine pesticides and polychlorinated biphenyls in air, grass and yak butter from Namco in the central Tibetan Plateau. Environmental Pollution. 2015; 201: 50–57. https://doi.org/10.1016/j.envpol.2015.02.037</mixed-citation><mixed-citation xml:lang="en">Wang C., Wang X., Yuan X., Ren J., Gong P. Organochlorine pesticides and polychlorinated biphenyls in air, grass and yak butter from Namco in the central Tibetan Plateau. Environmental Pollution. 2015; 201: 50–57. https://doi.org/10.1016/j.envpol.2015.02.037</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Balthazar C.F. et al. Sheep Milk: Physicochemical Characteristics and Relevance for Functional Food Development. Comprehensive Reviews in Food Science and Food Safety. 2017; 16(2): 247–262. https://doi.org/10.1111/1541-4337.12250</mixed-citation><mixed-citation xml:lang="en">Balthazar C.F. et al. Sheep Milk: Physicochemical Characteristics and Relevance for Functional Food Development. Comprehensive Reviews in Food Science and Food Safety. 2017; 16(2): 247–262. https://doi.org/10.1111/1541-4337.12250</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Lad S.S., Aparnathi K.D., Mehta B., Velpula S. Goat Milk in Human Nutrition and Health — A Review. International Journal of Current Microbiology and Applied Sciences. 2017; 6(5): 1781–1792. https://doi.org/10.20546/ijcmas.2017.605.194</mixed-citation><mixed-citation xml:lang="en">Lad S.S., Aparnathi K.D., Mehta B., Velpula S. Goat Milk in Human Nutrition and Health — A Review. International Journal of Current Microbiology and Applied Sciences. 2017; 6(5): 1781–1792. https://doi.org/10.20546/ijcmas.2017.605.194</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Venkatraman G. et al. Environmental impact and human health effects of polycyclic aromatic hydrocarbons and remedial strategies: A detailed review. Chemosphere. 2024; 351: 141227. https://doi.org/10.1016/j.chemosphere.2024.141227</mixed-citation><mixed-citation xml:lang="en">Venkatraman G. et al. Environmental impact and human health effects of polycyclic aromatic hydrocarbons and remedial strategies: A detailed review. Chemosphere. 2024; 351: 141227. https://doi.org/10.1016/j.chemosphere.2024.141227</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Domingo J.L., Nadal M. Human dietary exposure to polycyclic aromatic hydrocarbons: A review of the scientific literature. Food and Chemical Toxicology. 2015; 86: 144–153. https://doi.org/10.1016/j.fct.2015.10.002</mixed-citation><mixed-citation xml:lang="en">Domingo J.L., Nadal M. Human dietary exposure to polycyclic aromatic hydrocarbons: A review of the scientific literature. Food and Chemical Toxicology. 2015; 86: 144–153. https://doi.org/10.1016/j.fct.2015.10.002</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Ellickson K.M., Herbrandson C., Krause M.J., Pratt G.C., Kellock K.A. Comparative risk estimates of an expanded list of PAHs from community and source-influenced air sampling. Chemosphere. 2020; 253: 126680. https://doi.org/10.1016/j.chemosphere.2020.126680</mixed-citation><mixed-citation xml:lang="en">Ellickson K.M., Herbrandson C., Krause M.J., Pratt G.C., Kellock K.A. Comparative risk estimates of an expanded list of PAHs from community and source-influenced air sampling. Chemosphere. 2020; 253: 126680. https://doi.org/10.1016/j.chemosphere.2020.126680</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Cai C., Wu P., Zhou P., Yang D., Hu Z. Detection, Risk Assessment, and Survey of Four Polycyclic Aromatic Hydrocarbon Markers in Infant Formula Powder. Journal of Food Quality. 2020; 2020: 2959532. https://doi.org/10.1155/2020/2959532</mixed-citation><mixed-citation xml:lang="en">Cai C., Wu P., Zhou P., Yang D., Hu Z. Detection, Risk Assessment, and Survey of Four Polycyclic Aromatic Hydrocarbon Markers in Infant Formula Powder. Journal of Food Quality. 2020; 2020: 2959532. https://doi.org/10.1155/2020/2959532</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Amirdivani S. et al. Polycyclic aromatic hydrocarbons in milk and dairy products. International Journal of Dairy Technology. 2019; 72(1): 120–131. https://doi.org/10.1111/1471-0307.12567</mixed-citation><mixed-citation xml:lang="en">Amirdivani S. et al. Polycyclic aromatic hydrocarbons in milk and dairy products. International Journal of Dairy Technology. 2019; 72(1): 120–131. https://doi.org/10.1111/1471-0307.12567</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Yebra-Pimentel I., Fernández-González R., Martínez Carballo E., Simal-Gándara J. Searching ingredients polluted by polycyclic aromatic hydrocarbons in feeds due to atmospheric or pyrolytic sources. Food Chemistry. 2012; 135(3): 2043–2051. https://doi.org/10.1016/j.foodchem.2012.06.069</mixed-citation><mixed-citation xml:lang="en">Yebra-Pimentel I., Fernández-González R., Martínez Carballo E., Simal-Gándara J. Searching ingredients polluted by polycyclic aromatic hydrocarbons in feeds due to atmospheric or pyrolytic sources. Food Chemistry. 2012; 135(3): 2043–2051. https://doi.org/10.1016/j.foodchem.2012.06.069</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Ge Y., Wu S., Yan K. Concentrations, influencing factors, risk assessment methods, health hazards and analyses of polycyclic aromatic hydrocarbons in dairies: a review. Critical Reviews in Food Science and Nutrition. 2023; 63(23): 6168–6181. https://doi.org/10.1080/10408398.2022.2028717</mixed-citation><mixed-citation xml:lang="en">Ge Y., Wu S., Yan K. Concentrations, influencing factors, risk assessment methods, health hazards and analyses of polycyclic aromatic hydrocarbons in dairies: a review. Critical Reviews in Food Science and Nutrition. 2023; 63(23): 6168–6181. https://doi.org/10.1080/10408398.2022.2028717</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Rengarajan T., Rajendran P., Nandakumar N., Lokeshkumar B., Rajendran P., Nishigaki I. Exposure to polycyclic aromatic hydrocarbons with special focus on cancer. Asian Pacific Journal of Tropical Biomedicine. 2015; 5(3): 182–189. https://doi.org/10.1016/S2221-1691(15)30003-4</mixed-citation><mixed-citation xml:lang="en">Rengarajan T., Rajendran P., Nandakumar N., Lokeshkumar B., Rajendran P., Nishigaki I. Exposure to polycyclic aromatic hydrocarbons with special focus on cancer. Asian Pacific Journal of Tropical Biomedicine. 2015; 5(3): 182–189. https://doi.org/10.1016/S2221-1691(15)30003-4</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Shoaei F., Talebi-Ghane E., Amirsadeghi S., Mehri F. The investigation of polycyclic aromatic hydrocarbons (PAHs) in milk and its products: A global systematic review, meta-analysis and health risk assessment. International Dairy Journal. 2023; 142: 105645. https://doi.org/10.1016/j.idairyj.2023.105645</mixed-citation><mixed-citation xml:lang="en">Shoaei F., Talebi-Ghane E., Amirsadeghi S., Mehri F. The investigation of polycyclic aromatic hydrocarbons (PAHs) in milk and its products: A global systematic review, meta-analysis and health risk assessment. International Dairy Journal. 2023; 142: 105645. https://doi.org/10.1016/j.idairyj.2023.105645</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Chen B.-H., Inbaraj B.S., Hsu K.-C. Recent advances in the analysis of polycyclic aromatic hydrocarbons in food and water. Journal of Food and Drug Analysis. 2022; 30(4): 494–522. https://doi.org/10.38212/2224-6614.3429</mixed-citation><mixed-citation xml:lang="en">Chen B.-H., Inbaraj B.S., Hsu K.-C. Recent advances in the analysis of polycyclic aromatic hydrocarbons in food and water. Journal of Food and Drug Analysis. 2022; 30(4): 494–522. https://doi.org/10.38212/2224-6614.3429</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Mogashane T.M., Mokoena L., Tshilongo J. A Review on Recent Developments in the Extraction and Identification of Polycyclic Aromatic Hydrocarbons from Environmental Samples. Water. 2024; 16(17): 2520. https://doi.org/10.3390/w16172520</mixed-citation><mixed-citation xml:lang="en">Mogashane T.M., Mokoena L., Tshilongo J. A Review on Recent Developments in the Extraction and Identification of Polycyclic Aromatic Hydrocarbons from Environmental Samples. Water. 2024; 16(17): 2520. https://doi.org/10.3390/w16172520</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Soursou V., Campo J., Picó Y. Revisiting the analytical determination of PAHs in environmental samples: n update on recent advances. Trends in Environmental Analytical Chemistry. 2023; 37: e00195. https://doi.org/10.1016/j.teac.2023.e00195</mixed-citation><mixed-citation xml:lang="en">Soursou V., Campo J., Picó Y. Revisiting the analytical determination of PAHs in environmental samples: n update on recent advances. Trends in Environmental Analytical Chemistry. 2023; 37: e00195. https://doi.org/10.1016/j.teac.2023.e00195</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Liu L., Chen X., Duan Y., Wu Z., Xu L. Distribution, sources and health risk assessment of polycyclic aromatic hydrocarbons in urban soils under different landform conditions of Taiyuan, China. Frontiers in Environmental Science. 2024; 12: 1363297. https://doi.org/10.3389/fenvs.2024.1363297</mixed-citation><mixed-citation xml:lang="en">Liu L., Chen X., Duan Y., Wu Z., Xu L. Distribution, sources and health risk assessment of polycyclic aromatic hydrocarbons in urban soils under different landform conditions of Taiyuan, China. Frontiers in Environmental Science. 2024; 12: 1363297. https://doi.org/10.3389/fenvs.2024.1363297</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Sahoo B.M., Kumar B.V.V.R., Banik B.K., Borah P. Polyaromatic Hydrocarbons (PAHs): Structures, Synthesis and Their Biological Profile. Current Organic Synthesis. 2020; 17(8): 625–640. https://doi.org/10.2174/1570179417666200713182441</mixed-citation><mixed-citation xml:lang="en">Sahoo B.M., Kumar B.V.V.R., Banik B.K., Borah P. Polyaromatic Hydrocarbons (PAHs): Structures, Synthesis and Their Biological Profile. Current Organic Synthesis. 2020; 17(8): 625–640. https://doi.org/10.2174/1570179417666200713182441</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Santonicola S., Albrizio S., Murru N., Ferrante M.C., Mercogliano R. Study on the occurrence of polycyclic aromatic hydrocarbons in milk and meat/fish based baby food available in Italy. Chemosphere. 2017; 184: 467–472. https://doi.org/10.1016/j.chemosphere.2017.06.017</mixed-citation><mixed-citation xml:lang="en">Santonicola S., Albrizio S., Murru N., Ferrante M.C., Mercogliano R. Study on the occurrence of polycyclic aromatic hydrocarbons in milk and meat/fish based baby food available in Italy. Chemosphere. 2017; 184: 467–472. https://doi.org/10.1016/j.chemosphere.2017.06.017</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Chatzimichail S., Rahimi F., Saifuddin A., Surman A.J., Taylor-Robinson S.D., Salehi-Reyhani A. Hand-portable HPLC with broadband spectral detection enables analysis of complex polycyclic aromatic hydrocarbon mixtures. Communications Chemistry. 2021; 4: 17. https://doi.org/10.1038/s42004-021-00457-7</mixed-citation><mixed-citation xml:lang="en">Chatzimichail S., Rahimi F., Saifuddin A., Surman A.J., Taylor-Robinson S.D., Salehi-Reyhani A. Hand-portable HPLC with broadband spectral detection enables analysis of complex polycyclic aromatic hydrocarbon mixtures. Communications Chemistry. 2021; 4: 17. https://doi.org/10.1038/s42004-021-00457-7</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Liu T., Zhang L., Pan L., Yang D. Polycyclic Aromatic Hydrocarbons’ Impact on Crops and Occurrence, Sources, and Detection Methods in Food: A Review. Foods. 2024; 13(13): 1977. https://doi.org/10.3390/foods13131977</mixed-citation><mixed-citation xml:lang="en">Liu T., Zhang L., Pan L., Yang D. Polycyclic Aromatic Hydrocarbons’ Impact on Crops and Occurrence, Sources, and Detection Methods in Food: A Review. Foods. 2024; 13(13): 1977. https://doi.org/10.3390/foods13131977</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Sampaio G.R. et al. Polycyclic Aromatic Hydrocarbons in Foods: Biological Effects, Legislation, Occurrence, Analytical Methods, and Strategies to Reduce Their Formation. International Journal of Molecular Sciences. 2021; 22(11): 6010. https://doi.org/10.3390/ijms22116010</mixed-citation><mixed-citation xml:lang="en">Sampaio G.R. et al. Polycyclic Aromatic Hydrocarbons in Foods: Biological Effects, Legislation, Occurrence, Analytical Methods, and Strategies to Reduce Their Formation. International Journal of Molecular Sciences. 2021; 22(11): 6010. https://doi.org/10.3390/ijms22116010</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Islam F. et al. Natural Small Molecules in Gastrointestinal Tract and Associated Cancers: Molecular Insights and Targeted Therapies. Molecules. 2022; 27(17): 5686. https://doi.org/10.3390/molecules27175686</mixed-citation><mixed-citation xml:lang="en">Islam F. et al. Natural Small Molecules in Gastrointestinal Tract and Associated Cancers: Molecular Insights and Targeted Therapies. Molecules. 2022; 27(17): 5686. https://doi.org/10.3390/molecules27175686</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Korsh J., Shen A., Aliano K., Davenport T. Polycyclic Aromatic Hydrocarbons and Breast Cancer: A Review of the Literature. Breast Care. 2015; 10(5): 316–318. https://doi.org/10.1159/000436956</mixed-citation><mixed-citation xml:lang="en">Korsh J., Shen A., Aliano K., Davenport T. Polycyclic Aromatic Hydrocarbons and Breast Cancer: A Review of the Literature. Breast Care. 2015; 10(5): 316–318. https://doi.org/10.1159/000436956</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Mallah M.A. et al. Polycyclic aromatic hydrocarbon and its effects on human health: An overeview. Chemosphere. 2022; 296: 133948. https://doi.org/10.1016/j.chemosphere.2022.133948</mixed-citation><mixed-citation xml:lang="en">Mallah M.A. et al. Polycyclic aromatic hydrocarbon and its effects on human health: An overeview. Chemosphere. 2022; 296: 133948. https://doi.org/10.1016/j.chemosphere.2022.133948</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Bodduluru L.N., Kasala E.R., Barua C.C., Karnam K.C., Dahiya V., Ellutla M. Antiproliferative and antioxidant potential of hesperetin against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice. Chemico-Biological Interactions. 2015; 242: 345–352. https://doi.org/10.1016/j.cbi.2015.10.020</mixed-citation><mixed-citation xml:lang="en">Bodduluru L.N., Kasala E.R., Barua C.C., Karnam K.C., Dahiya V., Ellutla M. Antiproliferative and antioxidant potential of hesperetin against benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice. Chemico-Biological Interactions. 2015; 242: 345–352. https://doi.org/10.1016/j.cbi.2015.10.020</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Singh T.P., Arora S., Sarkar M. Yak milk and milk products: Functional, bioactive constituents and therapeutic potential. International Dairy Journal. 2023; 142: 105637. https://doi.org/10.1016/j.idairyj.2023.105637</mixed-citation><mixed-citation xml:lang="en">Singh T.P., Arora S., Sarkar M. Yak milk and milk products: Functional, bioactive constituents and therapeutic potential. International Dairy Journal. 2023; 142: 105637. https://doi.org/10.1016/j.idairyj.2023.105637</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Chalupa-Krebzdak S., Long C.J., Bohrer B.M. Nutrient density and nutritional value of milk and plant-based milk alternatives. International Dairy Journal. 2018; 87: 84–92. https://doi.org/10.1016/j.idairyj.2018.07.018</mixed-citation><mixed-citation xml:lang="en">Chalupa-Krebzdak S., Long C.J., Bohrer B.M. Nutrient density and nutritional value of milk and plant-based milk alternatives. International Dairy Journal. 2018; 87: 84–92. https://doi.org/10.1016/j.idairyj.2018.07.018</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Gil Á., Ortega R.M. Introduction and Executive Summary of the Supplement, Role of Milk and Dairy Products in Health and Prevention of Noncommunicable Chronic Diseases: A Series of Systematic Reviews. Advances in Nutrition. 2019; 10(S2): S67–S73. https://doi.org/10.1093/advances/nmz020</mixed-citation><mixed-citation xml:lang="en">Gil Á., Ortega R.M. Introduction and Executive Summary of the Supplement, Role of Milk and Dairy Products in Health and Prevention of Noncommunicable Chronic Diseases: A Series of Systematic Reviews. Advances in Nutrition. 2019; 10(S2): S67–S73. https://doi.org/10.1093/advances/nmz020</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Hu C. et al. Association of polycyclic aromatic hydrocarbons exposure with atherosclerotic cardiovascular disease risk: A role of mean platelet volume or club cell secretory protein. Environmental Pollution. 2018; 233: 45–53. https://doi.org/10.1016/j.envpol.2017.10.042</mixed-citation><mixed-citation xml:lang="en">Hu C. et al. Association of polycyclic aromatic hydrocarbons exposure with atherosclerotic cardiovascular disease risk: A role of mean platelet volume or club cell secretory protein. Environmental Pollution. 2018; 233: 45–53. https://doi.org/10.1016/j.envpol.2017.10.042</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Wei R., Yang M., Yao C., Chen W., Yang L., Ni J. Characteristics and Biodegradation of Nonextractable Residues of Polycyclic Aromatic Hydrocarbons in Historically Polluted Soils. Water Air and Soil Pollution. 2024; 235(5): 300. https://doi.org/10.1007/s11270-024-07115-3</mixed-citation><mixed-citation xml:lang="en">Wei R., Yang M., Yao C., Chen W., Yang L., Ni J. Characteristics and Biodegradation of Nonextractable Residues of Polycyclic Aromatic Hydrocarbons in Historically Polluted Soils. Water Air and Soil Pollution. 2024; 235(5): 300. https://doi.org/10.1007/s11270-024-07115-3</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Wang Z., Ng K., Warner R.D., Stockmann R., Fang Z. Reduction strategies for polycyclic aromatic hydrocarbons in processed foods. Comprehensive Reviews in Food Science and Food Safety. 2022; 21(2): 1598–1626. https://doi.org/10.1111/1541-4337.12905</mixed-citation><mixed-citation xml:lang="en">Wang Z., Ng K., Warner R.D., Stockmann R., Fang Z. Reduction strategies for polycyclic aromatic hydrocarbons in processed foods. Comprehensive Reviews in Food Science and Food Safety. 2022; 21(2): 1598–1626. https://doi.org/10.1111/1541-4337.12905</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Hamidi E.N., Hajeb P., Selamat J., Razis A.F.A. Polycyclic Aromatic Hydrocarbons (PAHs) and their Bioaccessibility in Meat: a Tool for Assessing Human Cancer Risk. Asian Pacific Journal of Cancer Prevention. 2016; 17(1): 15–23. http://doi.org/10.7314/APJCP.2016.17.1.15</mixed-citation><mixed-citation xml:lang="en">Hamidi E.N., Hajeb P., Selamat J., Razis A.F.A. Polycyclic Aromatic Hydrocarbons (PAHs) and their Bioaccessibility in Meat: a Tool for Assessing Human Cancer Risk. Asian Pacific Journal of Cancer Prevention. 2016; 17(1): 15–23. http://doi.org/10.7314/ APJCP.2016.17.1.15</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Onopiuk A., Kołodziejczak K., Szpicer A., Wojtasik-Kalinowska I., Wierzbicka A., Półtorak A. Analysis of factors that influence the PAH profile and amount in meat products subjected to thermal processing. Trends in Food Science and Technology. 2021; 115: 366–379. https://doi.org/10.1016/j.tifs.2021.06.043</mixed-citation><mixed-citation xml:lang="en">Onopiuk A., Kołodziejczak K., Szpicer A., Wojtasik-Kalinowska I., Wierzbicka A., Półtorak A. Analysis of factors that influence the PAH profile and amount in meat products subjected to thermal processing. Trends in Food Science and Technology. 2021; 115: 366–379. https://doi.org/10.1016/j.tifs.2021.06.043</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Chen B.H., Chen Y.C. Formation of Polycyclic Aromatic Hydrocarbons in the Smoke from Heated Model Lipids and Food Lipids. Journal of Agricultural and Food Chemistry. 2001; 49(11): 5238–5243. https://doi.org/10.1021/jf0106906</mixed-citation><mixed-citation xml:lang="en">Chen B.H., Chen Y.C. Formation of Polycyclic Aromatic Hydrocarbons in the Smoke from Heated Model Lipids and Food Lipids. Journal of Agricultural and Food Chemistry. 2001; 49(11): 5238–5243. https://doi.org/10.1021/jf0106906</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Maciejczyk M., Tyrpień-Golder K., Janoszka B., Gierat B., Muzyka R. Mutagenic and carcinogenic polycyclic aromatic hydrocarbons (PAHs) in food — occurrence, human health effects, and assessment methods of exposure. Environmental Medicine. 2023; 26(1–2): 8–15. https://doi.org/10.26444/ms/168971</mixed-citation><mixed-citation xml:lang="en">Maciejczyk M., Tyrpień-Golder K., Janoszka B., Gierat B., Muzyka R. Mutagenic and carcinogenic polycyclic aromatic hydrocarbons (PAHs) in food — occurrence, human health effects, and assessment methods of exposure. Environmental Medicine. 2023; 26(1–2): 8–15. https://doi.org/10.26444/ms/168971</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Polycyclic Aromatic Hydrocarbons in Food. Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on Polycyclic Aromatic Hydrocarbons in Food: Question N°EFSA-Q-2007-136. EFSA Journal No. 724. European Food Safety Authority. 2008; 114.</mixed-citation><mixed-citation xml:lang="en">Polycyclic Aromatic Hydrocarbons in Food. Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on Polycyclic Aromatic Hydrocarbons in Food: Question N°EFSA-Q-2007-136. EFSA Journal No. 724. European Food Safety Authority. 2008; 114.</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Zelinkova Z., Wenzl T. The Occurrence of 16 EPA PAHsin Food — A Review. Polycyclic Aromatic Compounds. 2015; 35(2–4): 248–284. https://doi.org/10.1080/10406638.2014.918550</mixed-citation><mixed-citation xml:lang="en">Zelinkova Z., Wenzl T. The Occurrence of 16 EPA PAHsin Food — A Review. Polycyclic Aromatic Compounds. 2015; 35(2–4): 248–284. https://doi.org/10.1080/10406638.2014.918550</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Majumder D., Sarkar C., Debnath R., Tribedi P., Maiti D. Mechanistic insight into the synergism of IL-27 and IL-28B in regulation of benzo(a)pyrene-induced lung carcinogenesis associated ROS/NF-κB/NLRP3 crosstalk. Chemico-Biological Interactions. 2022; 354: 109807. https://doi.org/10.1016/j.cbi.2022.109807</mixed-citation><mixed-citation xml:lang="en">Majumder D., Sarkar C., Debnath R., Tribedi P., Maiti D. Mechanistic insight into the synergism of IL-27 and IL-28B in regulation of benzo(a)pyrene-induced lung carcinogenesis associated ROS/NF-κB/NLRP3 crosstalk. Chemico-Biological Interactions. 2022; 354: 109807. https://doi.org/10.1016/j.cbi.2022.109807</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Badibostan H. et al. Polycyclic aromatic hydrocarbons in infant formulae, follow-on formulae, and baby foods in Iran: An assessment of risk. Food and Chemical Toxicology. 2019; 131: 110640. https://doi.org/10.1016/j.fct.2019.110640</mixed-citation><mixed-citation xml:lang="en">Badibostan H. et al. Polycyclic aromatic hydrocarbons in infant formulae, follow-on formulae, and baby foods in Iran: An assessment of risk. Food and Chemical Toxicology. 2019; 131: 110640. https://doi.org/10.1016/j.fct.2019.110640</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Nie C. et al. Structure, Biological Functions, Separation, Properties, and Potential Applications of Milk Fat Globule Membrane (MFGM): A Review. Nutrients. 2024; 16(5): 587. https://doi.org/10.3390/nu16050587</mixed-citation><mixed-citation xml:lang="en">Nie C. et al. Structure, Biological Functions, Separation, Properties, and Potential Applications of Milk Fat Globule Membrane (MFGM): A Review. Nutrients. 2024; 16(5): 587. https://doi.org/10.3390/nu16050587</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Belo R.F.C., Pissinatti R., de Souza S.V.C., Junqueira R.G. Evaluating Matrix Effects in the Analysis of Polycyclic Aromatic Hydrocarbons from Food: Can These Interferences Be Neglected for Isotope Dilution?. Food Analytical Methods. 2017; 10(5): 1488–1499. https://doi.org/10.1007/s12161-016-0706-0</mixed-citation><mixed-citation xml:lang="en">Belo R.F.C., Pissinatti R., de Souza S.V.C., Junqueira R.G. Evaluating Matrix Effects in the Analysis of Polycyclic Aromatic Hydrocarbons from Food: Can These Interferences Be Neglected for Isotope Dilution?. Food Analytical Methods. 2017; 10(5): 1488–1499. https://doi.org/10.1007/s12161-016-0706-0</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Anselmo S., Sancataldo G., Foderà V., Vetri V. α α-casein micellesmembranes interaction: Flower-like lipid protein coaggregates formation. Biochimica et Biophysica Acta (BBA) — General Subjects. 2022; 1866(10): 130196. https://doi.org/10.1016/j.bbagen.2022.130196</mixed-citation><mixed-citation xml:lang="en">Anselmo S., Sancataldo G., Foderà V., Vetri V. α α-casein micellesmembranes interaction: Flower-like lipid protein coaggregates formation. Biochimica et Biophysica Acta (BBA) — General Subjects. 2022; 1866(10): 130196. https://doi.org/10.1016/j.bbagen.2022.130196</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Palacios Colón L., Rascón A.J., Ballesteros E. Trace-Level Determination of Polycyclic Aromatic Hydrocarbons in Dairy Products Available in Spanish Supermarkets by Semi-Automated Solid-Phase Extraction and Gas Chromatography–Mass Spectrometry Detection. Foods. 2022; 11(5): 713. https://doi.org/10.3390/foods11050713</mixed-citation><mixed-citation xml:lang="en">Palacios Colón L., Rascón A.J., Ballesteros E. Trace-Level Determination of Polycyclic Aromatic Hydrocarbons in Dairy Products Available in Spanish Supermarkets by Semi-Automated Solid-Phase Extraction and Gas Chromatography–Mass Spectrometry Detection. Foods. 2022; 11(5): 713. https://doi.org/10.3390/foods11050713</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Alahmad W., Kaya S.I., Cetinkaya A., Varanusupakul P., Ozkan S.A. Green chemistry methods for food analysis: Overview of sample preparation and determination. Advances in Sample Preparation. 2023; 5: 100053. https://doi.org/10.1016/j.sampre.2023.100053</mixed-citation><mixed-citation xml:lang="en">Alahmad W., Kaya S.I., Cetinkaya A., Varanusupakul P., Ozkan S.A. Green chemistry methods for food analysis: Overview of sample preparation and determination. Advances in Sample Preparation. 2023; 5: 100053. https://doi.org/10.1016/j.sampre.2023.100053</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Jagirani M.S., Ozalp O., Soylak M. New Trend in the Extraction of Pesticides from the Environmental and Food Samples Applying Microextraction Based Green Chemistry Scenario: A Review. Critical Reviews in Analytical Chemistry. 2022; 52(6): 1343–1369. https://doi.org/10.1080/10408347.2021.1874867</mixed-citation><mixed-citation xml:lang="en">Jagirani M.S., Ozalp O., Soylak M. New Trend in the Extraction of Pesticides from the Environmental and Food Samples Applying Microextraction Based Green Chemistry Scenario: A Review. Critical Reviews in Analytical Chemistry. 2022; 52(6): 1343–1369. https://doi.org/10.1080/10408347.2021.1874867</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">Galmiche M., Delhomme O., François Y.-N., Millet M. Environmental analysis of polar and non-polar Polycyclic Aromatic Compounds in airborne particulate matter, settled dust and soot: Part II: Instrumental analysis and occurrence. TrAC Trends in Analytical Chemistry. 2021; 134: 116146. https://doi.org/10.1016/j.trac.2020.116146</mixed-citation><mixed-citation xml:lang="en">Galmiche M., Delhomme O., François Y.-N., Millet M. Environmental analysis of polar and non-polar Polycyclic Aromatic Compounds in airborne particulate matter, settled dust and soot: Part II: Instrumental analysis and occurrence. TrAC Trends in Analytical Chemistry. 2021; 134: 116146. https://doi.org/10.1016/j.trac.2020.116146</mixed-citation></citation-alternatives></ref><ref id="cit88"><label>88</label><citation-alternatives><mixed-citation xml:lang="ru">Rawash E.-S.A., Mohamed G.G., Souaya E.R., Khalil L.H., El-Chaghaby G.A., El-Gammal M.H. Distribution and Health Hazards of Polycyclic Aromatic Hydrocarbons in Egyptian Milk and Dairy-Based Products. Beverages. 2018; 4(3): 63. https://doi.org/10.3390/beverages4030063</mixed-citation><mixed-citation xml:lang="en">Rawash E.-S.A., Mohamed G.G., Souaya E.R., Khalil L.H., El-Chaghaby G.A., El-Gammal M.H. Distribution and Health Hazards of Polycyclic Aromatic Hydrocarbons in Egyptian Milk and DairyBased Products. Beverages. 2018; 4(3): 63. https://doi.org/10.3390/beverages4030063</mixed-citation></citation-alternatives></ref><ref id="cit89"><label>89</label><citation-alternatives><mixed-citation xml:lang="ru">Hasan G.M.M.A., Ali Shaikh M.A., Satter M.A., Hossain M.S. Detectionof indicator polychlorinated biphenyls (I-PCBs) and polycyclic aromatic hydrocarbons (PAHs) in cow milk from selected areas of Dhaka, Bangladesh and potential human health risks assessment. Toxicology Reports. 2022; 9: 1514–1522. https://doi.org/10.1016/j.toxrep.2022.07.008</mixed-citation><mixed-citation xml:lang="en">Hasan G.M.M.A., Ali Shaikh M.A., Satter M.A., Hossain M.S. Detectionof indicator polychlorinated biphenyls (I-PCBs) and polycyclic aromatic hydrocarbons (PAHs) in cow milk from selected areas of Dhaka, Bangladesh and potential human health risks assessment. Toxicology Reports. 2022; 9: 1514–1522. https://doi.org/10.1016/j.toxrep.2022.07.008</mixed-citation></citation-alternatives></ref><ref id="cit90"><label>90</label><citation-alternatives><mixed-citation xml:lang="ru">Rincón J.C. et al. Polycyclic aromatic hydrocarbons (PAHs) in four milk brands sold in Mexico City: evaluating three fat extraction methods. Revista mexicana de ciencias pecuarias. 2019; 10(4): 1064–1076. https://doi.org/10.22319/rmcp.v10i4.4763</mixed-citation><mixed-citation xml:lang="en">Rincón J.C. et al. Polycyclic aromatic hydrocarbons (PAHs) in four milk brands sold in Mexico City: evaluating three fat extraction methods. Revista mexicana de ciencias pecuarias. 2019; 10(4): 1064–1076. https://doi.org/10.22319/rmcp.v10i4.4763</mixed-citation></citation-alternatives></ref><ref id="cit91"><label>91</label><citation-alternatives><mixed-citation xml:lang="ru">Kishikawa N., Wada M., Kuroda N., Akiyama S., Nakashima K. Determination of polycyclic aromatic hydrocarbons in milk samples by high-performance liquid chromatography with fluorescence detection. Journal of Chromatography B. 2003; 789(2): 257–264. https://doi.org/10.1016/S1570-0232(03)00066-7</mixed-citation><mixed-citation xml:lang="en">Kishikawa N., Wada M., Kuroda N., Akiyama S., Nakashima K. Determination of polycyclic aromatic hydrocarbons in milk samples by high-performance liquid chromatography with fluorescence detection. Journal of Chromatography B. 2003; 789(2): 257–264. https://doi.org/10.1016/S1570-0232(03)00066-7</mixed-citation></citation-alternatives></ref><ref id="cit92"><label>92</label><citation-alternatives><mixed-citation xml:lang="ru">Yan K., Wu S., Gong G., Xin L., Ge Y. Simultaneous Determination of Typical Chlorinated, Oxygenated, and European Union Priority Polycyclic Aromatic Hydrocarbons in Milk Samples and Milk Powders. Journal of Agricultural and Food Chemistry. 2021; 69(13): 3923–3931. https://doi.org/10.1021/acs.jafc.1c00283</mixed-citation><mixed-citation xml:lang="en">Yan K., Wu S., Gong G., Xin L., Ge Y. Simultaneous Determination of Typical Chlorinated, Oxygenated, and European Union Priority Polycyclic Aromatic Hydrocarbons in Milk Samples and Milk Powders. Journal of Agricultural and Food Chemistry. 2021; 69(13): 3923–3931. https://doi.org/10.1021/acs.jafc.1c00283</mixed-citation></citation-alternatives></ref><ref id="cit93"><label>93</label><citation-alternatives><mixed-citation xml:lang="ru">Sun Y., Yan K., Wu S., Gong G. Occurrence, spatial distribution and impact factors of 16 polycyclic aromatic hydrocarbons in milks from nine countries. Food Control. 2020; 113: 107197. https://doi.org/10.1016/j.foodcont.2020.107197</mixed-citation><mixed-citation xml:lang="en">Sun Y., Yan K., Wu S., Gong G. Occurrence, spatial distribution and impact factors of 16 polycyclic aromatic hydrocarbons in milks from nine countries. Food Control. 2020; 113: 107197. https://doi.org/10.1016/j.foodcont.2020.107197</mixed-citation></citation-alternatives></ref><ref id="cit94"><label>94</label><citation-alternatives><mixed-citation xml:lang="ru">Aguinaga N., Campillo N., Viñas P., Hernández-Córdoba M. A headspace solid-phase microextraction procedure coupled with gas chromatography–mass spectrometry for the analysis of volatile polycyclic aromatic hydrocarbons in milk samples. Analytical and Bioanalytical Chemistry. 2008; 391(3): 753–758. https://doi.org/10.1007/s00216-008-1841-2</mixed-citation><mixed-citation xml:lang="en">Aguinaga N., Campillo N., Viñas P., Hernández-Córdoba M. A headspace solid-phase microextraction procedure coupled with gas chromatography–mass spectrometry for the analysis of volatile polycyclic aromatic hydrocarbons in milk samples. Analytical and Bioanalytical Chemistry. 2008; 391(3): 753–758. https://doi.org/10.1007/s00216-008-1841-2</mixed-citation></citation-alternatives></ref><ref id="cit95"><label>95</label><citation-alternatives><mixed-citation xml:lang="ru">Girelli A.M., Sperati D., Tarola A.M. Determination of polycyclic aromatic hydrocarbons in Italian milk by HPLC with fluorescence detection. Food Additives &amp; Contaminants: Part A. 2014; 31(4): 703–710. https://doi.org/10.1080/19440049.2013.878959</mixed-citation><mixed-citation xml:lang="en">Girelli A.M., Sperati D., Tarola A.M. Determination of polycyclic aromatic hydrocarbons in Italian milk by HPLC with fluorescence detection. Food Additives &amp; Contaminants: Part A. 2014; 31(4): 703–710. https://doi.org/10.1080/19440049.2013.878959</mixed-citation></citation-alternatives></ref><ref id="cit96"><label>96</label><citation-alternatives><mixed-citation xml:lang="ru">Dobrinas S., Soceanu A., Popescu V., Coatu V. Polycyclic aromatic hydrocarbons and pesticides in milk powder. Journal of Dairy Research. 2016; 83(2): 261–265. https://doi.org/10.1017/S0022029916000169</mixed-citation><mixed-citation xml:lang="en">Dobrinas S., Soceanu A., Popescu V., Coatu V. Polycyclic aromatic hydrocarbons and pesticides in milk powder. Journal of Dairy Research. 2016; 83(2): 261–265. https://doi.org/10.1017/S0022029916000169</mixed-citation></citation-alternatives></ref><ref id="cit97"><label>97</label><citation-alternatives><mixed-citation xml:lang="ru">Hollosi L., Wenzl T. Development and optimisation of a dopant assisted liquid chromatographic-atmospheric pressure photo ionisation-tandem mass spectrometric method for the determination of 15 + 1 EU priority PAHs in edible oils. Journal of Chromatography A. 2011; 1218(1): 23–31. https://doi.org/10.1016/j.chroma.2010.10.015</mixed-citation><mixed-citation xml:lang="en">Hollosi L., Wenzl T. Development and optimisation of a dopant assisted liquid chromatographic-atmospheric pressure photo ionisation-tandem mass spectrometric method for the determination of 15 + 1 EU priority PAHs in edible oils. Journal of Chromatography A. 2011; 1218(1): 23–31. https://doi.org/10.1016/j.chroma.2010.10.015</mixed-citation></citation-alternatives></ref><ref id="cit98"><label>98</label><citation-alternatives><mixed-citation xml:lang="ru">Hernández-Arteseros J.A., Beltrán J.L., Compañó R., Prat M.D. Fast-scanning fluorescence spectroscopy as a detection system in liquid chromatography for confirmatory analysis of flumequine and oxolinic acid. Journal of Chromatography A. 2002; 942(1‒2): 275–281. https://doi.org/10.1016/S0021-9673(01)01359-0</mixed-citation><mixed-citation xml:lang="en">Hernández-Arteseros J.A., Beltrán J.L., Compañó R., Prat M.D. Fast-scanning fluorescence spectroscopy as a detection system in liquid chromatography for confirmatory analysis of flumequine and oxolinic acid. Journal of Chromatography A. 2002; 942(1‒2): 275–281. https://doi.org/10.1016/S0021-9673(01)01359-0</mixed-citation></citation-alternatives></ref><ref id="cit99"><label>99</label><citation-alternatives><mixed-citation xml:lang="ru">Bertoz V., Purcaro G., Conchione C., Moret S. A Review on the Occurrence and Analytical Determination of PAHs in Olive Oils. Foods. 2021; 10(2): 324. https://doi.org/10.3390/foods10020324</mixed-citation><mixed-citation xml:lang="en">Bertoz V., Purcaro G., Conchione C., Moret S. A Review on the Occurrence and Analytical Determination of PAHs in Olive Oils. Foods. 2021; 10(2): 324. https://doi.org/10.3390/foods10020324</mixed-citation></citation-alternatives></ref><ref id="cit100"><label>100</label><citation-alternatives><mixed-citation xml:lang="ru">Avagyan R., Nyström R., Boman C., Westerholm R. Determination of hydroxylated polycyclic aromatic hydrocarbons by HPLC-photoionization tandem mass spectrometry in wood smoke particles and soil samples. Analytical and Bioanalytical Chemistry. 2015; 407(16): 4523–4534. https://doi.org/10.1007/s00216-015-8638-x</mixed-citation><mixed-citation xml:lang="en">Avagyan R., Nyström R., Boman C., Westerholm R. Determination of hydroxylated polycyclic aromatic hydrocarbons by HPLC-photoionization tandem mass spectrometry in wood smoke particles and soil samples. Analytical and Bioanalytical Chemistry. 2015; 407(16): 4523–4534. https://doi.org/10.1007/s00216-015-8638-x</mixed-citation></citation-alternatives></ref><ref id="cit101"><label>101</label><citation-alternatives><mixed-citation xml:lang="ru">Luque-Uría Á., Espinosa-Mansilla A., Durán-Merás I. Hplc-Fast Scanning Fluorimetric Detection Determination of Risk Exposure to Polycyclic Aromatics Hydrocarbons Biomarkers in Human Urine. Bioanalysis. 2017; 9(3): 265–278. https://doi.org/10.4155/bio-2016-0125</mixed-citation><mixed-citation xml:lang="en">Luque-Uría Á., Espinosa-Mansilla A., Durán-Merás I. Hplc-Fast Scanning Fluorimetric Detection Determination of Risk Exposure to Polycyclic Aromatics Hydrocarbons Biomarkers in Human Urine. Bioanalysis. 2017; 9(3): 265–278. https://doi.org/10.4155/bio-2016-0125</mixed-citation></citation-alternatives></ref><ref id="cit102"><label>102</label><citation-alternatives><mixed-citation xml:lang="ru">Martin-Tornero E., Luque-Uría A., Durán-Merás I., Espinosa-Mansilla A. A novel analytical methodology for the determination of hydroxy polycyclic aromatic hydrocarbons in breast and cow milk samples. Journal of Chromatography B. 2020; 1136: 121912. https://doi.org/10.1016/j.jchromb.2019.121912</mixed-citation><mixed-citation xml:lang="en">Martin-Tornero E., Luque-Uría A., Durán-Merás I., Espinosa-Mansilla A. A novel analytical methodology for the determination of hydroxy polycyclic aromatic hydrocarbons in breast and cow milk samples. Journal of Chromatography B. 2020; 1136: 121912. https://doi.org/10.1016/j.jchromb.2019.121912</mixed-citation></citation-alternatives></ref><ref id="cit103"><label>103</label><citation-alternatives><mixed-citation xml:lang="ru">Santonicola S. et al. Comparative study on the occurrence of polycyclic aromatic hydrocarbons in breast milk and infant formula and risk assessment. Chemosphere. 2017; 175: 383–390. https://doi.org/10.1016/j.chemosphere.2017.02.084</mixed-citation><mixed-citation xml:lang="en">Santonicola S. et al. Comparative study on the occurrence of polycyclic aromatic hydrocarbons in breast milk and infant formula and risk assessment. Chemosphere. 2017; 175: 383–390. https://doi.org/10.1016/j.chemosphere.2017.02.084</mixed-citation></citation-alternatives></ref><ref id="cit104"><label>104</label><citation-alternatives><mixed-citation xml:lang="ru">García Londoño V.A., Reynoso C.M., Resnik S. Polycyclic aromatic hydrocarbons in milk powders marketed in Uruguay. Food Additives &amp; Contaminants: Part B. 2017; 10(4): 284–291. https://doi.org/10.1080/19393210.2017.1349191</mixed-citation><mixed-citation xml:lang="en">García Londoño V.A., Reynoso C.M., Resnik S. Polycyclic aromatic hydrocarbons in milk powders marketed in Uruguay. Food Additives &amp; Contaminants: Part B. 2017; 10(4): 284–291. https://doi.org/10.1080/19393210.2017.1349191</mixed-citation></citation-alternatives></ref><ref id="cit105"><label>105</label><citation-alternatives><mixed-citation xml:lang="ru">Chung T.-L., Liao C.-J., Chen M.-F. Comparison of liquid–liquid extraction and solid-phase extraction for the determination of polycyclic aromatic hydrocarbons in the milk of Taiwan. Journal of the Taiwan Institute of Chemical Engineers. 2010; 41(2): 178–183. https://doi.org/10.1016/j.jtice.2009.07.003</mixed-citation><mixed-citation xml:lang="en">Chung T.-L., Liao C.-J., Chen M.-F. Comparison of liquid– liquid extraction and solid-phase extraction for the determination of polycyclic aromatic hydrocarbons in the milk of Taiwan. Journal of the Taiwan Institute of Chemical Engineers. 2010; 41(2): 178–183. https://doi.org/10.1016/j.jtice.2009.07.003</mixed-citation></citation-alternatives></ref><ref id="cit106"><label>106</label><citation-alternatives><mixed-citation xml:lang="ru">Grova N. et al. Detection of Polycyclic Aromatic Hydrocarbon Levels in Milk Collected Near Potential Contamination Sources. Journal of Agricultural and Food Chemistry. 2002; 50(16): 4640–4642. https://doi.org/10.1021/jf0201071</mixed-citation><mixed-citation xml:lang="en">Grova N. et al. Detection of Polycyclic Aromatic Hydrocarbon Levels in Milk Collected Near Potential Contamination Sources. Journal of Agricultural and Food Chemistry. 2002; 50(16): 4640–4642. https://doi.org/10.1021/jf0201071</mixed-citation></citation-alternatives></ref><ref id="cit107"><label>107</label><citation-alternatives><mixed-citation xml:lang="ru">Aguinaga N., Campillo N., Viñas P., Hernández-Córdoba M. Determination of 16 polycyclic aromatic hydrocarbons in milk and related products using solid-phase microextraction coupled to gas chromatography–mass spectrometry. Analytica Chimica Acta. 2007; 596(2): 285–290. https://doi.org/10.1016/j.aca.2007.06.005</mixed-citation><mixed-citation xml:lang="en">Aguinaga N., Campillo N., Viñas P., Hernández-Córdoba M. Determination of 16 polycyclic aromatic hydrocarbons in milk and related products using solid-phase microextraction coupled to gas chromatography–mass spectrometry. Analytica Chimica Acta. 2007; 596(2): 285–290. https://doi.org/10.1016/j.aca.2007.06.005</mixed-citation></citation-alternatives></ref><ref id="cit108"><label>108</label><citation-alternatives><mixed-citation xml:lang="ru">Lin W., Wei S., Jiang R., Zhu F., Ouyang G. Calibration of the complex matrix effects on the sampling of polycyclic aromatic hydrocarbons in milk samples using solid phase microextraction. Analytica Chimica Acta. 2016; 933: 117–123. https://doi.org/10.1016/j.aca.2016.05.045</mixed-citation><mixed-citation xml:lang="en">Lin W., Wei S., Jiang R., Zhu F., Ouyang G. Calibration of the complex matrix effects on the sampling of polycyclic aromatic hydrocarbons in milk samples using solid phase microextraction. Analytica Chimica Acta. 2016; 933: 117–123. https://doi.org/10.1016/j.aca.2016.05.045</mixed-citation></citation-alternatives></ref><ref id="cit109"><label>109</label><citation-alternatives><mixed-citation xml:lang="ru">Iwegbue C.M.A., Bassey F.I. Concentrations and health hazards of polycyclic aromatic hydrocarbons in selected commercial brands of milk. Journal of Food Measurement and Characterization. 2013; 7(4): 177–184. https://doi.org/10.1007/s11694-013-9153-4</mixed-citation><mixed-citation xml:lang="en">Iwegbue C.M.A., Bassey F.I. Concentrations and health hazards of polycyclic aromatic hydrocarbons in selected commercial brands of milk. Journal of Food Measurement and Characterization. 2013; 7(4): 177–184. https://doi.org/10.1007/s11694-013-9153-4</mixed-citation></citation-alternatives></ref><ref id="cit110"><label>110</label><citation-alternatives><mixed-citation xml:lang="ru">Viteri F., Sánchez N.E., Alexandrino K. Determination of Polycyclic Aromatic Hydrocarbons (PAHs) in Leaf and Bark Samples of Sambucus nigra Using High-Performance Liquid Chromatography (HPLC). Methods and Protocols. 2023; 6(1): 17. https://doi.org/10.3390/mps6010017</mixed-citation><mixed-citation xml:lang="en">Viteri F., Sánchez N.E., Alexandrino K. Determination of Polycyclic Aromatic Hydrocarbons (PAHs) in Leaf and Bark Samples of Sambucus nigra Using High-Performance Liquid Chromatography (HPLC). Methods and Protocols. 2023; 6(1): 17. https://doi.org/10.3390/mps6010017</mixed-citation></citation-alternatives></ref><ref id="cit111"><label>111</label><citation-alternatives><mixed-citation xml:lang="ru">Rey-Salgueiro L., Martínez-Carballo E., García-Falcón M.S., González-Barreiro C., Simal-Gándara J. Occurrence of polycyclic aromatic hydrocarbons and their hydroxylated metabolites in infant foods. Food Chemistry. 2009; 115(3): 814–819. https://doi.org/10.1016/j.foodchem.2008.12.095</mixed-citation><mixed-citation xml:lang="en">Rey-Salgueiro L., Martínez-Carballo E., García-Falcón M.S., González-Barreiro C., Simal-Gándara J. Occurrence of polycyclic aromatic hydrocarbons and their hydroxylated metabolites in infant foods. Food Chemistry. 2009; 115(3): 814–819. https://doi.org/10.1016/j.foodchem.2008.12.095</mixed-citation></citation-alternatives></ref><ref id="cit112"><label>112</label><citation-alternatives><mixed-citation xml:lang="ru">Naccari C., Cristani M., Giofrè F., Ferrante M., Siracusa L., Trombetta D. PAHs concentration in heat-treated milk samples. Food Research International. 2011; 44(3): 716–724. https://doi.org/10.1016/j.foodres.2010.12.029</mixed-citation><mixed-citation xml:lang="en">Naccari C., Cristani M., Giofrè F., Ferrante M., Siracusa L., Trombetta D. PAHs concentration in heat-treated milk samples. Food Research International. 2011; 44(3): 716–724. https://doi.org/10.1016/j.foodres.2010.12.029</mixed-citation></citation-alternatives></ref><ref id="cit113"><label>113</label><citation-alternatives><mixed-citation xml:lang="ru">Rey-Salgueiro L., García-Falcón M.S., Martínez-Carballo E., Simal-Gándara J. Effects of toasting procedures on the levels of polycyclic aromatic hydrocarbons in toasted bread. Food Chemistry. 2008; 108(2): 607–615. https://doi.org/10.1016/j.foodchem.2007.11.026</mixed-citation><mixed-citation xml:lang="en">Rey-Salgueiro L., García-Falcón M.S., Martínez-Carballo E., Simal-Gándara J. Effects of toasting procedures on the levels of polycyclic aromatic hydrocarbons in toasted bread. Food Chemistry. 2008; 108(2): 607–615. https://doi.org/10.1016/j.foodchem.2007.11.026</mixed-citation></citation-alternatives></ref><ref id="cit114"><label>114</label><citation-alternatives><mixed-citation xml:lang="ru">Garcia Londoño V.A., Garcia L.P., Scussel V.M., Resnik S. Polycyclic aromatic hydrocarbons in milk powders marketed in Argentina and Brazil. Food Additives &amp; Contaminants: Part A. 2013; 30(9): 1573–1580. https://doi.org/10.1080/19440049.2013.810347</mixed-citation><mixed-citation xml:lang="en">Garcia Londoño V.A., Garcia L.P., Scussel V.M., Resnik S. Polycyclic aromatic hydrocarbons in milk powders marketed in Argentina and Brazil. Food Additives &amp; Contaminants: Part A. 2013; 30(9): 1573–1580. https://doi.org/10.1080/19440049.2013.810347</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
