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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vetpress</journal-id><journal-title-group><journal-title xml:lang="ru">Аграрная наука</journal-title><trans-title-group xml:lang="en"><trans-title>Agrarian science</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0869-8155</issn><issn pub-type="epub">2686-701X</issn><publisher><publisher-name>Редакция журнала "Аграрная наука"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.32634/0869-8155-2026-404-03-65-74</article-id><article-id custom-type="elpub" pub-id-type="custom">vetpress-4056</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЗООТЕХНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ZOOTECHNICS</subject></subj-group></article-categories><title-group><article-title>Повышение результативности искусственного осеменения  у высокопродуктивных коров с иммунологическим бесплодием</article-title><trans-title-group xml:lang="en"><trans-title>Improving the efficiency of artificial insemination in high-yielding cows with immunological infertility</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6236-8634</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абилов</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Abilov</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ахмедага Имаш оглы Абилов , доктор биологических наук, профессор, заслуженный деятель науки РФ, главный научный сотрудник</p><p>п. Дубровицы д. 60, г.о. Подольск, Московская область, 142132</p></bio><bio xml:lang="en"><p>Akhmedaga Imash ogly Abilov, Doctor of Biological Sciences, Professor, Honored Scientist of the Russian Federation, Chief Researcher </p><p>60 Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132</p></bio><email xlink:type="simple">ahmed.abilov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3861-4465</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комбарова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kombarova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нина Анатольевна Комбарова , кандидат биологических наук </p><p>п. Дубровицы д. 60, г.о. Подольск, Московская область, 142132</p></bio><bio xml:lang="en"><p>Nina Anatolyevna Kombarova , Candidate of Biological Sciences</p><p>60 Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132</p></bio><email xlink:type="simple">komnina@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1039-0375</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Турбина</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Turbina</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виктория Владимировна Турбина, аспирант </p><p>п. Дубровицы д. 60, г.о. Подольск, Московская область, 142132</p></bio><bio xml:lang="en"><p>Victoria Vladimirovna Turbina, postgraduate student </p><p>60 Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральный исследовательский центр животноводства — ВИЖ им. академика Л.К. Эрнста</institution><country>Россия</country></aff><aff xml:lang="en"><institution>L.K. Ernst Federal Research Center for Animal Husbandry</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>19</day><month>03</month><year>2026</year></pub-date><volume>0</volume><issue>3</issue><fpage>65</fpage><lpage>74</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Абилов А.И., Комбарова Н.А., Турбина В.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Абилов А.И., Комбарова Н.А., Турбина В.В.</copyright-holder><copyright-holder xml:lang="en">Abilov A.I., Kombarova N.A., Turbina V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vetpress.ru/jour/article/view/4056">https://www.vetpress.ru/jour/article/view/4056</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. В настоящее время в молочном скотоводстве все чаще диагностируют случаи бесплодия у высокопродуктивных коров. Ускоренная селекция требует комплексного анализа воспроизводства с целью повышения его эффективности.</p></sec><sec><title>Методы</title><p>Методы. Исследования проведены и результаты апробированы в хозяйствах Московской и Орловской областей. В исследованиях участвовали 52 быка-производителя и 246 коров, у 72 из которых был предварительно установлен диагноз «иммунное бесплодие».</p></sec><sec><title>Результаты</title><p>Результаты. Разработан новый диагностический протокол, позволивший повысить результативность искусственного осеменения у высокопродуктивных генетически ценных коров, имевших в анамнезе более 6 безрезультатных попыток осеменения в течение 8 и более месяцев. Основу протокола составляет индивидуальный подбор быков-производителей методом титрования их нативной спермы в аллосыворотке крови каждой проблемной коровы. Для индивидуального подбора использовали быков, прошедших полную андрологическую диспансеризацию и не имевших титров спермальных ауто антител в собственной сыворотке крови. В разработку метода входила подготовка и проведение искусственного осеменения, определение стельности методом ультразвукового исследования.</p></sec><sec><title>Выводы</title><p>Выводы. Представлено решение проблемы иммунологического бесплодия у многократно безуспешно осеменяемых коров при отсутствии клинических гинекологических патологий. Апробация данного протокола позволила получить стельность в 44,4% случаев у яловых коров с предварительным диагнозом иммунное бесплодие.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. Currently, in dairy farming, cases of infertility in highly productive cows are being diagnosed with increasing frequency. Accelerated selection requires a comprehensive analysis of reproduction in order to improve its efficiency.</p></sec><sec><title>Methods</title><p>Methods. The research was conducted and the results were tested on farms in the Moscow and Oryol regions. The studies involved 52 service bulls and 246 cows, 72 of which had been previously diagnosed with “immune infertility.”</p></sec><sec><title>Results</title><p>Results. A new diagnostic protocol was developed, which improved the effectiveness of artificial insemination in highly productive, genetically valuable cows with a history of more than 6 unsuccessful insemination attempts over 8 or more months. The basis of the protocol is the individual selection of service bulls by titrating their native semen in the alloserum of each problem cow. For individual selection, we used bulls that had undergone a complete andrological examination and had no titers of sperm autoantibodies in their own blood serum. The development of the method included the preparation and execution of artificial insemination, and the determination of pregnancy via ultrasound examination.</p></sec><sec><title>Conclusions</title><p>Conclusions. A solution to the problem of immunological infertility in repeatedly unsuccessfully inseminated cows with no clinical gynecological pathologies is presented. Testing of this protocol resulted in pregnancy in 44.4% of cases in barren cows with a preliminary diagnosis of immune infertility.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>иммунологическое бесплодие</kwd><kwd>аутоантитела</kwd><kwd>аллоантитела</kwd><kwd>яловость</kwd><kwd>индивидуальный подбор быков-производителей</kwd><kwd>результативность осеменения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>immunological infertility</kwd><kwd>autoantibodies</kwd><kwd>alloantibodies</kwd><kwd>barrenness</kwd><kwd>individual  selection of sires</kwd><kwd>insemination success</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Научная статья подготовлена в рамках выполнения исследований  по государственному заданию научно-исследовательских работ № FGGN-2024-0013 ФГБНУ ФИЦ ВИЖ им. ак.Л.К. Эрнста.</funding-statement><funding-statement xml:lang="en">The scientific article was prepared as part of the research carried out under the state assignment for scientific research work No. FGGN-2024-0013 of the Federal State Budgetary Scientific Institution, L.K. Ernst Federal Research Center for Animal Husbandry</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Устименко А.В., Абилов А.И., Козменков П.Л. Послеотельные отклонения у коров и первотелок и способы их коррекции. Аграрная наука. 2025; (10): 45–57. https://doi.org/10.32634/0869-8155-2025-399-10-45-57</mixed-citation><mixed-citation xml:lang="en">Ustimenko A.V., Abilov A.I., Kozmenkov P.L. Postpartum deviations in cows and first-calf heifers and methods for their correction. 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