Integral indices of intoxication of dogs affected by babesiosis

Abstract

The article presents the results of scientific study of the dependence of the severity of clinical signs on the degree of endogenous intoxication (hereinafter DEI) of the body affected by babesiosis. There were examined hematological, biochemical indicators of 20 dogs of different breeds and sexes. The dogs were divided into 3 groups according to the severity of clinical signs - mild, moderate and severe. In each group, the hematological and biochemical indicators were examined and compared, and integral indices for each animal were calculated. The examination of blood hematologic indicators revealed leukopenia, monocytosis, expressed thrombocytopenia, and in some cases, the presence of hemolytic hypochromic microcytic anemia. In all three groups, the biochemical blood test revealed increased AST, alkaline phosphatase and LDH. In the course of the studies, the severity of the disease was correlated with DEI. Thus, in 40% of the cases the indicators of the first and second groups were correlated in severity with the clinical picture, but in the rest cases, there were significant differences. The moderate DEI occurred much more often than the mild or severe -45% against 25% and 30%, respectively. It was noted that in some dogs the clinical picture did not correspond to the DEI, which indicates that the identification of integral indices is the most reliable method for the right treatment.