Inactivated marked vaccine against Aujeszky’s disease
https://doi.org/10.32634/0869-8155-2021-347-4-85-88
Abstract
The article presents data on the results of assessing the intensity and duration of the immune response in piglets to the introduction of inactivated marked vaccine against Aujeszky’s disease in comparison with similar indicators for immunization with live labeled and inactivated unlabeled vaccines. Immunization with an inactivated marked vaccine induced the production of virus neutralizing antibodies at a high level.
About the Authors
E. V. Shemelkov
LLC “Vetbiohim”
Russian Federation
Russian Federation
Ph.D., Head of the quality control department
105120, Moscow, 3rd Syromyatnichesky per., 3/9
O. A. Verkhovsky
Scientific Research Institute for Diagnostics and Prevention of Human and Animal Diseases
Russian Federation
Russian Federation
Doctor of Biological Sciences, President
123098, Moscow, st. Gamalei, 16-2
T. I. Aliper
LLC “Vetbiohim”
Russian Federation
Russian Federation
Doctor of Biological Sciences, Chairman of the Board of Directors
105120, Moscow, 3rd Syromyatnichesky per., 3/9
T. S. Kulikova
LLC “Vetbiohim”
Russian Federation
Russian Federation
employee of the quality control department
105120, Moscow, 3rd Syromyatnichesky per., 3/9
S. A. Afanasyev
LLC “Vetbiohim”
Russian Federation
Russian Federation
microbiologist of the quality control department
105120, Moscow, 3rd Syromyatnichesky per., 3/9
References
1. Lviv DK. Viruses and viral infections of humans and animals. M.: “Meditsinskoe informationnoe agenstvo”. 2013.1200 p. (In Russ).
2. Sergeev VA, Nepoklonov EA, Aliper TI. Viruses and viral vaccines. M.: Biblionika. 2007. 524 p. (In Russ).
3. Syurin VN, Samuilenko AYa, Soloviev BV, Fomina NV. Viral diseases of animals. M.: VNIITIBP, 1998. 928 p. (In Russ).
4. Shemelkov EV, Kotelnikov AP, Kulikova TS, Mishin AM, Verkhovsky OA, Aliper TI. Development and evaluation of the effectiveness of live labeled vaccine against Aujeszky’s disease “VERRES-BAgE-” Veterinariya. 2018 (6): 21-27. (In Russ.).
5. Chernov AN. Peculiarities of the epizootic situation and assessment of the effectiveness of vaccine prophylaxis in Aujeszky’s disease. In the collection: Scientific notes of the Kazan State Academy of Veterinary Medicine. N.E. Bauman. Kazan. 2013; 213: 314-318 p. (In Russ).
6. Gu Z, Hou C, Sun H, Yang W, Dong J, Bai J, Jiang P. Emergence of highly virulent pseudorabies virus in southern China. Can J Vet Res. 2015 Jul 31; 79(3):221-8.
7. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals chapter 2.1.2. http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.01.02_AUJESZKYS_DIS.pdf
8. Kukushkin SA. Fundamentals of control and eradication of Aujeszky’s disease in pig farms in Russia. Veterinariya. 2015 (4): 13-18. (In Russ.).
9. Ma W, Lager KM, Richt JA, Stoffregen WC, Zhou F, Yoon KJ. Development of real-time polymerase chain reaction assays for rapid detection and differentiation of wild-type pseudorabies and gene-deleted vaccine viruses. J Vet Diagn Invest. 2008 Jul; 20(4):440-7. https://doi.org/10.1177/104063870802000405
10. Bayry J. (editor) Emerging and Re-emerging Infectious Diseases of Livestock. Springer International Publishing AG 2017 513 p.
11. Baborenko EP. Study of postvaccinal immunity after use of marked strain-based vaccine against Aujeszky’s disease in pigs. Veterinary Science Today. 2016;(4):49-52. (In Russ.).
12. Dong B, Zarlenga DS, Ren X. An overview of live attenuated recombinant pseudorabies viruses for use as novel vaccines. J Immunol Res. Published online 2014 Jun 5. doi: 10.1155/2014/824630
Review
For citations:
Shemelkov E.V., Verkhovsky O.A., Aliper T.I., Kulikova T.S., Afanasyev S.A. Inactivated marked vaccine against Aujeszky’s disease. Agrarian science. 2021;(4S):85-88. (In Russ.) https://doi.org/10.32634/0869-8155-2021-347-4-85-88
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