The effect of helminthic invasion on the level of post-vaccination antibodies against canine distemper and parvovirus enteritis in dogs
https://doi.org/10.32634/0869-8155-2021-352-9-18-24
Abstract
Relevance. In the instructions for the use of vaccines for dogs, there is a clause prescribing mandatory anthelmintic treatment of the animal before vaccination. This is really a correct indication, since it is well known that helminthiasis affects the animal’s body, disrupting many metabolic processes and causing a number of pathological changes in the body. Helminthic infestations affect the level of immunity of the animal by changing the level of immunoglobulins, causing changes in the T- and B-systems of immunity. However, there is no data available in the literature describing how helminths affect the production of post-vaccination antibodies. This paper describes an experiment aimed at establishing how toxocara invasion affects the formation of post- vaccination immunity against canine distemper and parvovirus enteritis in dogs.
Methods. The research was conducted in a shelter for neglected animals in Vitebsk. The object of research was two dogs aged 4 years and seven puppies aged 1–2 months. The animals were divided into two groups. The first group included one adult dog and four puppies. The second group included an adult dog and three puppies. Animals of both groups were vaccinated against carnivorous plague and parvovirus enteritis, but only animals of the second group were dewormed.
Results. By evaluating the results of the study, it was found that helminthic invasion really hinders the development of post-vaccination immunity.
About the Authors
V. A. Gerasimchik
Vitebsk State Academy of Veterinary Medicine
Belarus
Belarus
Gerasimchik Vladimir Aleksandrovich, Doctor of Veterinary Sciences, Professor, Head of the Department of Diseases of Small Animals and Birds of the Vitebsk State Academy of Veterinary Medicine
210026, Vitebsk, 1st Dovatora st., 7/11
E. S. Eremeev
Vitebsk State Academy of Veterinary Medicine; Shelter for homeless animals in Vitebsk
Belarus
Belarus
Eremeev Evgenij Sergeevich, post-graduate student of the Department of Diseases of Small Animals and Birds of the Vitebsk State Academy of Veterinary Medicine, veterinarian of the shelter for homeless animals in Vitebsk
210026, Vitebsk, 1st Dovatora st., 7/11
210101, Vitebsk, Starobabinovich`s tract st., 29
References
1. Gerasimchik, V. A. The effectiveness of prazitab-plus in uncinariasis of dogs / V. A. Gerasimchik, I. Shaaban / Scientific search for youth of the XXI century. // Materials of the XI International Scientific Conference of students and undergraduates dedicated to the 170th anniversary of the BSSA (Gorki, December 2–4, 2009).– Gorki, 2009. – pp. 84–85.
2. Daugalieva, E. H. Immune status and ways of its correction in helminthiasis of farm animals / E. H. Daugalieva, V. V. Filippov. Moscow: Agropromizdat, 1991 – 188 p.
3. Yershov, V. S. Problems of immunity and allergy in helminthiasis / V. S. Yershov / / Probl. vet. immunology. Moscow: Agropromizdat, 1985. – pp. 17–22.
4. Immunocorrection in clinical veterinary medicine / P. A. Krasochko [et al.]; edited by P. A. Krasochko. – Minsk: Technoperspektiva, 2008. – 507 p.
5. Kolevatova, A. I. Clinical course of experimental uncinariosis of dogs in the process of pathogen development: abstract. dis. ... Candidate of Veterinary Sciences / A. I. Kolevatova. – Kirov, 1959 – – 22 p.
6. Kondrakhin, I. P. Clinical laboratory diagnostics in veterinary medicine: reference edition / I. P. Kondrakhin, N. B. Kurilov, A. G. Malakhov ; edited by I. P. Kondrakhin. – Moscow: Agropromizdat, 1985. – 287 p.
7. Kopanev Yu. A. Clinical and microbiological features of the current course of ascariasis and enterobiosis in children: Abstract of the dissertation of the candidate of medical sciences: 03.00.07, 14.00.09. / Russian Medical Academy of Postgraduate Education. – M., 2001. – 27 p.
8. Leikina, E. S. The role of allergic reactions of immediate and delayed types in the mechanisms of immunity in helminthiasis / / Med. parasitol. and parasitic. diseases. – 1975. – No. 4. – pp. 477–484.
9. Moskalets O. V., Paleev F. N., Kotova A. A., Naumova T. E., etc. Pathogenesis of secondary immune insufficiency syndrome and approaches to its treatment / / Clinical medicine. – 2002. – Vol. 80, No. 11. – pp. 18–23.
10. Ozeretskovskaya N. N. Organ pathology in the acute stage of tissue helminthiasis: the role of blood and tissue eosinophilia, immunoglobulinemia E, G4 and factors that induce an immune response // Medical parasitology and parasitic diseases. – 2000. – No. 3. – pp. 3–8.
11. Ozeretskovskaya N. N. Organ pathology in the chronic stage of tissue helminthiasis: the role of blood and tissue eosinophilia, immunoglobulinemia E, G4 and factors that induce an immune response. // Medical parasitology and parasitic diseases. – 2000. – No. 4. – p. 9–14.
12. Ozeretskovskaya N. N. Blood eosinophilia and immunoglobulinemia E: features of regulation in helminthiasis and allergic diseases // Medical parasitology and parasitic diseases. – 1997. – No. 2. – pp. 3–9.
13. Poletaeva, O. G. The phenomenon of rosette formation by B-lymphocytes of the spleen of mice invaded by Ascarissuum larvae / / Med. parasitol. and parasitic. diseases. – 1978. – No. 4. – pp. 34–38.
14. Reutskaya, D. I. Immunity in parvovirus enteritis of dogs / D. I. Reutskaya // Bulletin of the Altai State University–2003–No. 1–p. 228–229.
15. Chudnaya, L. M., Oksiuk V. G., Shekhter A. G., etc. The level of post-vaccination immunity to diphtheria, tetanus and polio, depending on the frequency of vaccinations // Journal of Microbiology, Epidemiology, Immunology. – 1991. – No. 1. – pp. 46–49.
16. Yakubovsky, M. V. Immunity in helminthiasis of animals / M. V. Yakubovsky, T. Ya. Myastsova, V. P. Olenich / / Izvestia of the Academy of Agrarian Sciences of the Republic of BelarusNo. 4 1997. –Minsk, 2012. –pp. 74–77.
Review
For citations:
Gerasimchik V.A., Eremeev E.S. The effect of helminthic invasion on the level of post-vaccination antibodies against canine distemper and parvovirus enteritis in dogs. Agrarian science. 2021;(9):18-24. (In Russ.) https://doi.org/10.32634/0869-8155-2021-352-9-18-24
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