Preventive efficacy of Forticarb in piroplasmidosis of cattle

Abstract

Relevance. Chemoprophylaxis of piroplasmidosis of cattle in disadvantaged farms due to the lack of vaccination is carried out mainly with the use of DAC, Neosidin. It was found that polyethylene glycol prolongs the preventive effect of these drugs for 20–21 days, naganin with polyvinylpyralidone — for 25 days. Carrying out of treatments with such intervals during the disease season is unacceptable, since it adversely affects the state of the animal organism, contributes to the emergence of resistant types of pathogens and leads to unjustified consumption of drugs. In this regard, finding the treatment and prevention of piroplasmosis of cattle is an urgent task.

Materials and мethods. The comparative prophylactic effect of chemotherapy drugs in piroplasmidoses was studied on 45 animals, which were divided into 3 groups (15 heads). The first group (n = 15) served as control; Neosidin 7% was used at a dose of 3.5 mg/kg. In the second group (n = 15) animals were injected with Neosidin 7% in dose 3.5 ml/kg, with polyethylene glycol (PEG) 20 g per 100 ml of water. The third group (n = 15) was injected with Forticarb at a dose of 2.5 mg/kg at the rate of 2.5 ml/100 kg of live weight, once, intramuscularly. Animals were observed during 40 days. Sick were treated with Forticarb, in dose 4 ml/100 kg.

Results. For the first time under production conditions, the preventive efficacy of Forticarb in piroplasmidoses of cattle was studied, which is manifested by increased safety and obtaining of additional products during the season of diseases. The results showed that the drug Forticarb protects animals during 30 days from diseases.