The use of vitamin complex in combination with chemotherapy in theileriosis of cattle

Relevance. In the Caspian region of Russia, blood parasitic diseases are one of the most common diseases of cattle, which cause significant economic damage to livestock farms due to reduced productivity and death of animals. According to natural and climatic conditions and zonal features, the Republic of Dagestan is a favorable habitat for ixodic mites, the main carriers of pyroplasmidosis pathogens, in particular Theileria annulata. In spring, cattle with impaired resistance, weakened after wintering, are seriously ill with pyroplasmidosis, especially teileriosis, after getting over the gum, rumination, intestinal work, milk yield, and general reaction to the environment recover to physiological norm for a long time. In this regard, further improvement of existing and the search for new methods that ensure maximum conservation of animals from these invasions, with minimal effort and money, remains an urgent task. The aim of the study was to determine the effectiveness of “Delagil” in the combined use of “Ursoferanforte” in spontaneous bovine taileriosis.

Methods. Methods for determining therapeutic efficacy were formed by experimental and control groups of 30 heads of different ages with spontaneous tayleriosis in varying degrees of severity of the disease with a temperature reaction within 40.4 ± 0.03 — 41.5 ± 0.09 °C, parasitemia — 5.47 ± 0.3 — 25.18 ± 0.31% in 100 fields of view of the microscope. In the control group, “Delagil” was used in its pure form at a dose of 2 g / 100 kg (20 mg / kg by DV) (orally) with water in the form of a suspension. In the experimental group, treatment was carried out comprehensively — “Delagil” in the indicated doses in combination with the drug “Ursoferan-forte” in a dose of 10–25 ml (once, intramuscularly).

Results. The use of antimalarial “Delagil” in combination with the drug “Ursoferan-forte” (in combination) increases the effectiveness to 93.3% and avoids significant economic losses. Currently, the safety of susceptible animals from teileriosis is becoming possible with the combined use of chemotherapeutic drugs.

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