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Analysis of risk factors for the development of squamous cell carcinoma and evaluation of approaches to its treatment

https://doi.org/10.32634/0869-8155-2025-394-05-48-55

Abstract

The paper presents an analysis of risk factors contributing to the development of squamous cell carcinoma and assesses approaches to its treatment. Understanding the nature of the risks associated with mortality from squamous cell carcinoma is important for both humans and various animal species diagnosed with it. In recent years, oncological diseases have been gaining momentum around the world. Squamous cell carcinoma is no exception, due to its high prevalence among humans and animals. Of particular interest is the diagnosis of the disease in the early stages, which significantly increases the chances of a positive outcome. Of particular importance are the tasks associated with timely diagnosis and differentiation of oncology from other diseases with similar symptoms. The authors assessed the effectiveness of different approaches to the treatment of squamous cell carcinoma in small domestic animals chosen as the object of study to increase the statistical accuracy of the results and conclusions obtained, since only clinical conditions allow for a detailed medical history of each animal and obtaining dynamic data. Another reason for conducting animal studies in clinical settings is the bioethics of collecting experimental material, which may reduce the number of laboratory tests on model animals, as an alternative to experiments with deliberately immersing animals in a state of disease with a high probability of their lethal outcome. Studying the predisposition and mechanisms of development of squamous cell carcinoma using animals as an example may further contribute to the development of new methods for diagnosing and treating this disease in humans. Studying oncofactors that stimulate the development of carcinoma will help identify risk groups and develop preventive measures aimed at preventing the spread of the disease, as far as possible with the current level of development of medical knowledge.

About the Authors

Yu. O. Lyashchuk
Federal Scientific Agroengineering Center VIM
Russian Federation

Yulia Olegovna Lyashchuk, Candidate of Technical Sciences, Researcher

5 1st Institutsky proezd, Moscow, 109428



K. I. Romanov
Ryazan State Agrotechnological University named after P.A. Kostychev
Russian Federation

Kirill Igorevich Romanov, Candidate of Biological Sciences, Associate Professor of the Department of Anatomy and Physiology of Animals

1 Kostychev Str., Ryazan, 390044



K. A. Ivanishchev
Ryazan State Agrotechnological University named after P.A. Kostychev
Russian Federation

Konstantin Alexandrovich Ivanishchev, Candidate of Veterinary Sciences, Associate Professor of the Department of Anatomy and Physiology of Animals

1 Kostychev Str., Ryazan, 390044



A. V. Kurmatova
Veterinary clinic “Doctor Vet”
Russian Federation

Arina Vladislavovna Kurmatova, Assistant Surgeon

37 Novoselov Str., Ryazan, 390048



G. N. Samarin
Federal Scientific Agroengineering Center VIM
Russian Federation

Gennady Nikolayevich Samarin, Doctor of Technical Sciences, Chief Researcher, Head of Laboratory

5 1st Institutsky proezd, Moscow, 109428



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Review

For citations:


Lyashchuk Yu.O., Romanov K.I., Ivanishchev K.A., Kurmatova A.V., Samarin G.N. Analysis of risk factors for the development of squamous cell carcinoma and evaluation of approaches to its treatment. Agrarian science. 2025;(5):48-55. (In Russ.) https://doi.org/10.32634/0869-8155-2025-394-05-48-55

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ISSN 0869-8155 (Print)
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