Evaluation of the effectiveness of mastitis vaccination in cows at one of the livestock farms in the Ryazan region

Relevance. Mastitis remains one of the most widespread and economically significant diseases in dairy cattle breeding and is a serious problem both in terms of productivity and animal health, as well as in terms of economic losses associated with the costs of veterinary measures and the disposal of inappropriate milk sales.

The article evaluates the effectiveness of three vaccines of different dosage forms with different antigenic composition used for the specific prevention of mastitis in dairy cows in the Russian Federation, shows the impact of immunization on animal health.

The aim of the work is a comparative assessment of the preventive and cost effectiveness of vaccines of various dosage forms with different antigenic compositions used for the specific prevention of mastitis in dairy cows in the field.

Methods. The study was conducted on 580 heads of Holstein rock. The NSC was determined by the viscometric method. Bacteriological analysis of milk was performed by seeding on Columbia blood agar with culture identification by API systems and MALDI-TOF MS. Two Spanish-made cow mastitis vaccines and one Russian-made biopreparation were used in the work, and the vaccine series had valid expiration dates. The animals were vaccinated in accordance with the instructions for the use of immunobiological preparations.

Results. It has been established that the effectiveness of specific prevention of cow mastitis directly depends on the antigenic composition of the vaccines used. Thus, the vaccine in the form of an emulsion (Spain), due to its limited antigenic composition, has demonstrated its ineffectiveness against the dominant pathogen in the farm S. agalactiae. The use of the vaccine in suspension form (Spain) was accompanied by delayed manifestation of mastitis, which indicates the partial effectiveness of the drug against pathogens whose antigens are part of the drug. Vaccine in the form of an emulsion (Russia) it contributed to a significant reduction in the incidence of mastitis in subclinical and clinical forms. The analysis of vaccination costs showed significant economic benefits, even despite the insignificant detection of the incidence of mastitis among vaccinated animals.

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