Clinical and ophthalmological characteristics of corneal regeneration during surgical treatment using the amniotic membrane in dogs
https://doi.org/10.32634/0869-8155-2025-399-10-8-16
Abstract
The paper presents data from morphometric studies of the structures of the wall of the small intestine of broiler chickens, especially the layers of its mucous membrane under the influence of stressors, as well as against the background of pharmacological prophylaxis with the pharmacological agent “Peak-antistress”. The first group (control) received complete compound feed, the second (1st experimental) received complete compound feed, including the anti-stress feed additive “Peak-antistress” at a dose of 1.27 kg per 1 ton of feed 5 days before slaughter, the third (2nd experimental) received the feed additive “Peak-antistress” with the inclusion of It contains L-carnitine in a total dose of 1.7 kg per 1 ton of feed 5 days before slaughter. Under the short-term effect of technological stresses on the body of the experimental bird, a change in the morphometric parameters of the small intestine wall was observed, accompanied by a decrease in the thickness of the mucous membrane, the size (height and width) of the villi. Under the influence of pharmacological prophylaxis — the feed additive “Peak-antistress” — and in combination with L-carnitine in the experimental groups, an increase in the thickness of the membranes of the wall of the small intestine, especially mucosa and muscle, was noted, which gives a synergistic effect, L-carnitine potentiates the action of pharmaceutical substances included in the composition of the drug “Peakantistress”. Under the influence of anti-stress therapy, a significant increase in the mucous membrane occurs, especially the duodenum and jejunum due to an increase in the height of the villi and a decrease in the diameter of the crypts and the height of the epithelium.
Keywords
Supporting agencies: The study was funded by the Russian Science Foundation grant No. 24-26-20039. https://rscf.ru/project/24-26-20039.
About the Authors
A. V. Miftakhutdinov
South Ural State Agrarian University
Russian Federation
Russian Federation
Alevtin Viktorovich Miftakhutdinov - Doctor of Biological Sciences, Professor, Head of the
Department of Morphology, Physiology and Pharmacology,
13 Gagarin Str., Troitsk, 457100
E. A. Nogovitsina
South Ural State Agrarian University
Russian Federation
Russian Federation
Elena Aleksandrovna Nogovitsina - Candidate of Biological Sciences, Associate Professor of the Department of Morphology, Physiology and Pharmacology,
13 Gagarin Str., Troitsk, 457100
E. V. Akentieva
South Ural State Agrarian University
Russian Federation
Russian Federation
Elizaveta Viktorovna Akentieva - Student,
13 Gagarin Str., Troitsk, 457100
Yu. S. Shakirova
South Ural State Agrarian University
Russian Federation
Russian Federation
Yulia Sabiryanovna Shakirova - Student,
13 Gagarin Str., Troitsk, 457100
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Review
For citations:
Miftakhutdinov A.V., Nogovitsina E.A., Akentieva E.V., Shakirova Yu.S. Clinical and ophthalmological characteristics of corneal regeneration during surgical treatment using the amniotic membrane in dogs. Agrarian science. 2025;(10):8-16. (In Russ.) https://doi.org/10.32634/0869-8155-2025-399-10-8-16
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