The use of phonophoresis and wound healing dressing based on “Collachit-FA” collagen chitosan complex in the treatment of superficial wounds in rabbits
https://doi.org/10.32634/0869-8155-2025-399-10-25-31
Abstract
Relevance. Superficial wounds are one of the most common injuries in domestic and farm animals. Their healing is complicated by factors such as conditions of detention, lifestyle and untimely access to veterinary specialists. In this regard, the search for effective treatment methods that accelerate tissue regeneration remains an urgent task in veterinary medicine.
The aim of the work is to evaluate the effectiveness of the combined use of the “Collachit-FA” wound healing coating and phonophoresis in comparison with using only the “Collachit-FA” wound coating.
Methods. The work was performed on the basis of the animal hospital, the Vita clinic and the histological laboratory of the Krasnoyarsk State Agrarian University. For the experiment, female hybrid rabbits were selected according to the principle of analogues, kept in the same conditions. The material for the study was modeled wounds, tissue samples for histological studies. The research methodology included morphometric, macroscopic and histological methods.
Results. It was found that in the experimental group (phonophoresis + “Collachit-FA”), the wound surface area decreased faster: by the 28th day, it was 3.86±0.23 cm2 (6.8% less than in the control group; p < 0.05). Histological analysis confirmed the acceleration of reparative processes: by day 21, complete restoration of the epithelium was observed in the experimental group, while in the control group the basement membrane remained uneven and the epithelium was immature. By day 28, complete healing of the skin was noted in the experimental groups. Thus, the combination of “Collachit-FA” wound healing coating with ultrasound stimulation significantly accelerates tissue regeneration in animals.
About the Author
N. A. Chuev
Krasnoyarsk State Agrarian University
Russian Federation
Russian Federation
Nikita Anatolyevich Chuev - Graduate Student,
90 Mira Ave., Krasnoyarsk, 660049
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Review
For citations:
Chuev N.A. The use of phonophoresis and wound healing dressing based on “Collachit-FA” collagen chitosan complex in the treatment of superficial wounds in rabbits. Agrarian science. 2025;(10):25-31. (In Russ.) https://doi.org/10.32634/0869-8155-2025-399-10-25-31
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