Comparative population-genetic analysis of the gene pool of the Red Gorbatov breed based on SNP markers
https://doi.org/10.32634/0869-8155-2025-399-10-133-141
Abstract
Comparative studies of the origin of the pool red Gorbatov breed (n = 129) with world breeds of red root cattle were conducted. With the similarity coefficient K = 2, animals of the desired breed differed to the greatest extent from the red Belarusian cattle, Holstein black and redmotley color, red Danish (including the gene pool group), but were more similar in genomic components to the red steppe and Suksun breeds. With K = 4, the greatest homogeneity of the red Gorbatov cattle groups was observed, and with K = 6–10, strong fragmentation in the form of complex genotypes with other compared breeds was noted. It was found that the highest frequency of haplotype clusters was localized on chromosome 6 of cattle for 6 compared red root breeds (37196103–37698422 bp, detectable region), as well as on chromosome 7 of cattle for 6 compared breeds (530447:1915174 bp, detectable region). Analysis of genome regions by QTL showed that the ROH/Fst, hapflk/Fst and hapflk/ROH genes identified by different methods were associated with the fatty acid composition of milk (including conjugated FA), body weight and size of animals, average daily weight gain and feed intake, eye muscle area, milk fat and protein yield, fertility indicators (calving difficulty). A more detailed examination of the LD values by breed and chromosomes at distances of 0–30 kb, 30–70 kb, 70–100 kb and 100–200 kb at r2 > 0.30 revealed pairs of SNPs in fractional terms, most often found on the chromosomes of cattle BTA6, BTA9, BTA14.
Supporting agencies: The research was carried out with the support of the Russian Science Foundation using grant funds No. 23-46-10002.
About the Authors
I. S. Nedashkovsky
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Igor Sergeevich Nedashkovsky - Candidate of Biological Sciences, Senior Researcher,
Head of the National Catalog Department,
60 Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132
A. A. Sermyagin
Russian Research Institute of Farm Animal Genetics and Breeding — Branch of L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Alexander Alexandrovich Sermyagin - Candidate of Agricultural Sciences, Director,
55А Moskovskoe shosse, Pushkin, St. Petersburg, 196601
E. N. Naryshkina
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Elena Nikolaevna Naryshkina - Candidate of Agricultural Sciences, Senior Researcher,
Head of the Department of Population Genetics and Genetic Foundations of Animal Breeding,
60 Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132
A. S. Abdelmanova
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Alexandra Sergeevna Abdelmanova - Doctor of Biological Sciences, Senior Researcher,
Head of the Laboratory of Genetic Monitoring of Farm Animal Resources,
60 Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132
N. A. Zinovieva
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Natalia Anatolyevna Zinovieva - Doctor of Biological Sciences, Professor, Academician
of the Russian Academy of Sciences, Director,
60 Dubrovitsy, Podolsk Municipal District, Moscow Region, 142132
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Review
For citations:
Nedashkovsky I.S., Sermyagin A.A., Naryshkina E.N., Abdelmanova A.S., Zinovieva N.A. Comparative population-genetic analysis of the gene pool of the Red Gorbatov breed based on SNP markers. Agrarian science. 2025;(10):133-141. (In Russ.) https://doi.org/10.32634/0869-8155-2025-399-10-133-141
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