General clinical blood parameters of service dogs under the influence of potassium humate

This study investigated the effects of a feed additive containing potassium humate on hematological parameters in working dogs (n = 20) subjected to significant physical exertion. Such intense exercise can induce metabolic disorders, inflammatory processes, and endogenous intoxication, which negatively affect erythrocyte function, blood rheology, and tissue oxygenation. Humic acids, known for their antioxidant, detoxifying, and hemostasis-modulating properties, were administered at a dosage of 25 mg daily for 21 days as a supplement to the main diet. Hematological analysis, performed using an analyzer and phase-contrast microscopy, revealed significant improvements in hematological parameters: an 18.2% increase in red blood cell count, a 16.8% increase in hemoglobin levels, and a 17.7% improvement in the Mean Corpuscular Hemoglobin Concentration (MCHC). Morphological changes in erythrocytes included a 100% increase in normocytes relative to the baseline value, as well as reductions in microcytosis (25.0%), hypochromia (14.3%), echinocytosis (30.0%), and spherocytosis (50.0%). These data indicate an enhanced oxygen transport capacity, improved erythrocyte morphology, and a decreased number of pathological cell forms. No adverse reactions were detected during the experiment. This study demonstrates the efficacy of humic acids in stabilizing hematological parameters and improving erythrocyte function in dogs under heavy physical loads.

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