Level of prooxidant-antioxidant status in highly productive cows with comorbid obstetric, gynecological and orthopedic pathology
https://doi.org/10.32634/0869-8155-2024-386-9-34-39
Abstract
The lipid peroxidation and antioxidant defense system is a balanced system responsible for the processing and utilization of lipids in the body’s cells. It plays an important role in lipid metabolism, cell protection and overall health of the body. Its proper functioning is necessary to ensure optimal functioning of cells and organs throughout the body. The article clinically and experimentally substantiates the pathogenetic role of lipid peroxidation products and the level of antioxidant protection in cows with endometritis and purulent-necrotic processes in the finger area, as well as with the comorbid course of endometritis and orthopedic pathology. It has been shown that multimorbid manifestation is accompanied by a more severe course than individual diseases. It has been established that the development of postpartum endometritis and purulent-necrotic lesions of the limbs in cows is accompanied by a highly significant increase in lipid peroxidation products in the blood serum against the background of a decrease in the amount of antioxidant enzymes, with the exception of ceruloplasmin. Moreover, these changes are accompanied by a sharp jump in the comorbid course of endometritis and orthopedic pathology in highly productive animals.
Keywords
Supporting agencies: The research was supported by the Russian Science Foundation grant No. 24-26-00172 https://rscf.ru/project/24-26-00172/
About the Authors
V. I. Lutsaу
Russian Biotechnological Universit
Russian Federation
Russian Federation
Vladimir Ivanovich Lutsaу, Doctor of Veterinary Sciences, Head of the Department of Veterinary Medicine
11 Volokolamskoe highway, Moscow, 125080
V. D. Sibirtsev
Russian Biotechnological Universit
Russian Federation
Russian Federation
Vladimir Dmitrievich Sibirtsev, Postgraduate Student of the Department of Veterinary Medicine
11 Volokolamskoe highway, Moscow, 125080
A. M. Nefedov
Russian Biotechnological Universit
Russian Federation
Russian Federation
Anton Maksimovich Nefedov, Postgraduate Student of the Department of Veterinary Medicine
11 Volokolamskoe highway, Moscow, 125080
P. A. Rudenko
Russian Biotechnological Universit; Peoples’ Friendship University of Russia named after Patrice Lumumba
Russian Federation
Russian Federation
Pavel Anatolyevich Rudenko, Doctor of Veterinary Sciences, Professor of the Department of Veterinary Medicine
11 Volokolamskoe highway, Moscow, 125080
6 Miklukho-Maclay Str., Moscow, 117198
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Review
For citations:
Lutsaу V.I., Sibirtsev V.D., Nefedov A.M., Rudenko P.A. Level of prooxidant-antioxidant status in highly productive cows with comorbid obstetric, gynecological and orthopedic pathology. Agrarian science. 2024;1(9):34-39. (In Russ.) https://doi.org/10.32634/0869-8155-2024-386-9-34-39
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