Генетическая архитектура мясных показателей свиноматок крупной белой породы

В настоящее время полногеномный анализ ассоциаций является современным и достоверным методом анализа геномной информации о животных, а также определения взаимосвязи «генотип — фенотип». Данное исследование направлено на использование метода GWAS для выявления значимых SNP, находящихся внутри или сцепленных с генами по мясным показателям свиней крупной белой породы — толщине шпика над 6–7-м и 10–12-м позвонками, глубине «мышечного глазка». Проведенный GWA-анализ показал наличие 60 генов, из которых 17 имеют связь с биологическим функционалом, аннотация которых проведена в программе DAVID. Были обнаружены три гена, имеющие кодификацию в базе Pig QTL. Гены были разделены на 10 групп на основании генной онтологии (GO). Из всех генов наибольший интерес представляет ген AUTS2, расположенный на 3-й хромосоме и прогнозирующий количество желтых тел у свиноматок. Результаты данной научной работы будут способствовать разработке системы генетической оценки и улучшению мясных качеств свиней.

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