Genetic architecture of meat traits in Large White sows
E. A. Trebunskikh,
A. A. Belous,
P. I. Otradnov,
A. F. Conte,
A. A. Reshetnikova,
V. V. Volkova,
N. A. Zinovieva https://doi.org/10.32634/0869-8155-2024-386-9-71-76
Abstract
Currently, genome-wide association analysis is a modern and reliable method for analyzing genomic information about animals, as well as determining the “genotype — phenotype” relationship. This study aims to use the GWAS method to identify significant SNPs located within or linked to genes for meat traits in Large White pigs — backfat thickness over the 6–7th and 10–12th vertebrae, and loin muscle depth. The conducted GWA analysis revealed 60 genes, of which 17 are associated with biological functionality, annotated using the DAVID program. Three genes were found to have codification in the Pig QTL database. The genes were divided into 10 groups based on gene ontology (GO). Of all the genes, the AUTS2 gene, located on chromosome 3 and predicting the number of corpora lutea in sows, is of greatest interest. The results of this scientific work will contribute to the development of a genetic evaluation system and improvement of meat qualities in pigs.
Keywords
GWAS,
meat characteristics,
structural annotation of genes,
functional annotation of genes,
QTL database,
large white sows
Supporting agencies: This research was funded by Russian Sciece Foundation No. 21-76-10038.
About the Authors
E. A. Trebunskikh
Top Gen Breeding and Hybrid Center LLC
Russian Federation
Russian Federation
Elena Alekseevna Trebunskikh, Deputy Director of Breeding
1 Kalinin Str., Verkhnyaya Khava village, Verkhnekhava district, Voronezh region, 396110
A. A. Belous
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Anna Alexandrovna Belous, Candidate of Biological Sciences, Associate Professor, Head of the Laboratory
60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132
P. I. Otradnov
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Pyotr Ilyich Otradnov, Junior Researcher
60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132
A. F. Conte
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Alexander Fedorovich Conte, Candidate of Agricultural Sciences, Senior Researcher
60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132
A. A. Reshetnikova
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Anastasia Alexandrovna Reshetnikova, Junior Research Assistant
60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132
V. V. Volkova
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Valeria Vladimirovna Volkova, Candidate of Biological Sciences, Senior Researcher
60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132
N. A. Zinovieva
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation
Russian Federation
Natalia Anatolyevna Zinovieva, Director, Doctor of Biological Sciences, Academician of the Russian Academy of Sciences, Professor
60 Dubrovitsy settlement, Podolsk city district, Moscow region, 142132
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Review
For citations:
Trebunskikh E.A., Belous A.A., Otradnov P.I., Conte A.F., Reshetnikova A.A., Volkova V.V., Zinovieva N.A. Genetic architecture of meat traits in Large White sows. Agrarian science. 2024;1(9):71-76. (In Russ.) https://doi.org/10.32634/0869-8155-2024-386-9-71-76
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