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Determination of TNFAIP3, CDS1 and MTAP gene expression in a population of large white pigs

https://doi.org/10.32634/0869-8155-2025-391-02-95-100

Abstract

In modern molecular biology and genetics, the study of gene expression plays a key role in understanding the mechanisms of development and functioning of living organisms. In pig farming, where breeding and genetics are important tools for improving animal productivity and resilience, gene expression analysis can provide valuable material for breeding programs. The article devoted to determining the expression of TNFAIP3, CDS1 and MTAP genes in a population of large white pigs is an in-depth study in the field of molecular genetics and animal breeding. The above-mentioned genes were selected in connection with their supposed role in regulating the immune response, metabolism and development of the body. As a result of real-time PCR analysis, differences in the expression of CDS1 (CDP-diacylglycerine synthase) genes in lung and kidney tissues were shown compared with expression in heart tissues. In addition, it was found that the expression level of the MTAR (methylthioadenosine phosphorylase) gene differs in lung and spleen tissues compared to other studied organs. The results of the study may have significant implications for pig breeding programs, as they provide information on genetic factors affecting the productivity, sustainability and quality of pig meat. In addition, the article may be of interest to a wide range of specialists in the field of molecular genetics, animal breeding and veterinary medicine, as it demonstrates the application of modern methods of molecular biology to solve urgent problems in animal husbandry.

About the Authors

A. A. Reshetnikova
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation

Anastasia Alexandrovna Reshetnikova - Junior Researcher.

60 Dubrovitsy, Podolsk, Moscow region, 142132



A. A. Belous
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation

Anna Alexandrovna Belous - Candidate of Biological Sciences, Associate Professor, Head of the Laboratory.

60 Dubrovitsy, Podolsk, Moscow region, 142132



P. I. Otradnov
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation

Petr Ilich Otradnov - Junior Research Assistant.

60 Dubrovitsy, Podolsk, Moscow region, 142132



E. A. Trebunskih
LLC Breeding and Hybrid Center “Top Gene”
Russian Federation

Elena Alekseevna Trebunskikh - Deputy Director of Breeding.

1 Kalinin Str., Verkhnyaya Khava village, Verkhnekhava district, Voronezh region, 396110



A. F. Conte
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation

Alexander Fedorovich Conte - Candidate of Agricultural Sciences, Senior Researcher.

60 Dubrovitsy, Podolsk, Moscow region, 142132



V. V. Volkova
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation

Valeria Vladimirovna Volkova - Candidate of Biological Sciences, Senior Researcher.

60 Dubrovitsy, Podolsk, Moscow region, 142132



N. A. Zinovieva
L.K. Ernst Federal Research Center for Animal Husbandry
Russian Federation

Natalia Anatolyevna Zinovieva - Doctor of Biological Sciences, Academician of the Russian Academy of Sciences, Professor, Director.

60 Dubrovitsy, Podolsk, Moscow region, 142132



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For citations:


Reshetnikova A.A., Belous A.A., Otradnov P.I., Trebunskih E.A., Conte A.F., Volkova V.V., Zinovieva N.A. Determination of TNFAIP3, CDS1 and MTAP gene expression in a population of large white pigs. Agrarian science. 2025;(2):95-100. (In Russ.) https://doi.org/10.32634/0869-8155-2025-391-02-95-100

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