Efficiency of therapy of highly productive cows with comorbid obstetric-gynecological and orthopedic pathology

In veterinary practice, there is a problem of comorbid course of various diseases, which are caused by associations of opportunistic microflora present in farm biocenoses. Comorbid course of gynecological and orthopedic pathologies in cows causes significant economic damage, which is associated with a decrease in milk productivity and an increase in the cost of diagnostics, treatment and prevention of veterinary measures. Therefore, due to the high level of reproductive dysfunction and purulent-necrotic lesions in the hooves of cows, it is necessary to look for effective and pathogenetically substantiated methods of therapeutic action on these pathologies. In this manuscript, clinical and morphological control of the effectiveness of treatment with various schemes of highly productive cows with comorbid course of postpartum endometritis and orthopedic pathology is carried out. It has been established that the most effective treatment regimen for highly productive animals with comorbid postpartum acute purulent-catarrhal endometritis and purulent-necrotic lesions in the toe area is the treatment of cows in the 1st experimental group. This is evidenced by the absence of complications, faster overall clinical improvement by 8.67 days (p < 0.001) and the occurrence of estrus 37.2 days (p < 0.001) earlier, when compared with the basic treatment. The effectiveness of the treatment of cows in the 1st experimental group is supported by the positive dynamics of stabilization of the blood levels of HGB, RBC, PLT and WBC, when compared with the indicators of animals in other experimental groups.

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