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Dynamics of antioxidant system indices and lipid peroxidation products in cows with comorbid obstetric-gynecological and orthopedic pathology

https://doi.org/10.32634/0869-8155-2025-395-06-40-47

Abstract

In this manuscript, a pro-oxidant-antioxidant control of the effectiveness of treatment with various schemes of highly productive cows in the comorbid course of postpartum acute purulent-catarrhal endometritis and purulent-necrotic disease in the finger area was carried out.

As a result of the conducted studies, it was found that the most effective complex treatment for highly productive cows with comorbid course of postpartum endometritis and orthopedic pathology turned out to be scheme I of the experimental group, as evidenced by the general condition of the experimental animals, as well as the positive dynamics of the increase in the number of antioxidant enzymes against the background of a decrease in the amount of lipoperoxidation products in the blood serum. It was found that the complex treatment of highly productive cows according to scheme I contributes to a faster overall clinical improvement already on day 9.42±0.25 (***), the onset of sexual hunting on day 52.00±0.88 (***), and the absence of complications when compared with the basic treatment of animals of the IV experimental group. It should be noted that in blood serum samples of animals of the First experimental group, the level of POL products (DC, MDA, MSM) decreases significantly faster against the background of an increase in the AOS system (SOD, CT, GLP, OAOA) compared with other experimental groups, reaching reference values.

About the Authors

V. I. Lutsaу
Russian Biotechnological University
Russian Federation

Vladimir Ivanovich Lutsaу, Doctor of Veterinary Sciences, Head of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080



P. A. Rudenko
Russian Biotechnological University; Patrice Lumumba Peoples’ Friendship University of Russia
Russian Federation

Pavel Anatolievich Rudenko, Doctor of Veterinary Sciences, Professor of the Department of Veterinary Medicine; Professor of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080

6 Miklukho-Maclay Str., Moscow, 117198



V. D. Sibirtsev
Russian Biotechnological University
Russian Federation

Vladimir Dmitrievich Sibirtsev, Postgraduate Student of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080



A. M. Nefedov
Russian Biotechnological University
Russian Federation

Anton Maksimovich Nefedov, Рostgraduate Student of the Department of Veterinary Medicine

11 Volokolamskoe highway, Moscow, 125080



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Review

For citations:


Lutsaу V.I., Rudenko P.A., Sibirtsev V.D., Nefedov A.M. Dynamics of antioxidant system indices and lipid peroxidation products in cows with comorbid obstetric-gynecological and orthopedic pathology. Agrarian science. 2025;1(6):40-47. (In Russ.) https://doi.org/10.32634/0869-8155-2025-395-06-40-47

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