The influence of the drug Acid Lac on the state of natural resistance of the body of broiler chickens

Relevance. In modern conditions of intensive poultry farming, antibiotics are often used unsystematically for therapeutic and prophylactic purposes, which contributes to the widespread development of antibiotic-resistant strains of microorganisms. This circumstance requires the study and introduction into agricultural production of feed additives that have a beneficial effect on the body and productivity of poultry. Preparations based on organic acids, which have antibacterial and growth-stimulating effects, have great potential.
Methods. Four groups of day-old broiler chickens of the Arbor Acres cross were formed. Birds of the II, III and IV experimental groups in addition to the main diet received Acid Lac at the rate of 2.0, 3.0 and 4.0 g/kg of feed. Chickens of the I group served as a control. Blood was collected from birds of all groups at the age of one day, 7, 14, 28, 35 and 42 days for immunological studies. At the end of growing, the broilers were slaughtered with subsequent collection of the thymus, spleen and bursa of Fabricius to determine the weight of the organs.
Results. The use of Acid Lac in broiler chicken diets contributed to the enhancement of humoral factors of natural resistance of the organism. By the end of rearing, the lysozyme activity of blood serum in the birds of the experimental groups exceeded the control values by 6.63–7.77%, bactericidal — by 5.37–6.04%. The phagocytic activity of blood leukocytes increased by 6.87–13.46%, the phagocytic index — by 21.0–28.0%. A decrease in the number of circulating immune complexes by 5.88–9.83% was observed. The weight of the thymus, bursa of Fabricius, spleen was higher in broiler chickens of the experimental groups.

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