Model for studying bovine leukemia virus
https://doi.org/10.32634/0869-8155-2018-320-11-21-23
Abstract
In a series of three tests, a process of infection through the milk obtained from a cow infected with bovine leukemia virus was simulated in calves under natural conditions. The test on rabbits showed that their infection with bovine leukemia virus is possible through alimentary canal. Feeding rabbits with milk or milk with blood taken from the cow infected with bovine leukemia virus caused the following signs: antibodies to virus antigens in the serum and proviral DNA in the blood lymphocytes. Such infection of the rabbits after oral administration of milk obtained from the cow infected with bovine leukemia virus indicates the risk of infection for people. The minimum doses of proviral DNA were established. These doses cause infectious process after intravenous and oral administration of 3,6x107 copies and 2,7x 109 copies, respectively.
About the Authors
T. V. Stepanova
All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Scriabin and Y.R. Kovalenko
Russian Federation
Russian Federation
L. A. Ivanova
All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Scriabin and Y.R. Kovalenko
Russian Federation
Russian Federation
M. I. Gulyukin
All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Scriabin and Y.R. Kovalenko
Russian Federation
Russian Federation
N. G. Kozyreva
All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Scriabin and Y.R. Kovalenko
Russian Federation
Russian Federation
V. V. Stafford
All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Scriabin and Y.R. Kovalenko
Russian Federation
Russian Federation
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Review
For citations:
Stepanova T.V., Ivanova L.A., Gulyukin M.I., Kozyreva N.G., Stafford V.V. Model for studying bovine leukemia virus. Agrarian science. 2018;(11-12):21-23. (In Russ.) https://doi.org/10.32634/0869-8155-2018-320-11-21-23
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