Effectiveness of “Avecardit®” use in dogs with mitral valve endocardiosis under anesthesia for oral cavity sanitation: a comparative study of hemodynamics

Mitral valve endocardiosis is one of the most common heart diseases in dogs and poses a significant risk during dental surgery under general anesthesia.

The aim of the study was to evaluate the effectiveness of the pimobendan-based drug “Avecardit®” in tooth extraction in dogs with chronic valvular regurgitation. valve regurgitation. The study involved 40 clinically healthy dogs (from the point of view of other organs) with verified grade B2 mitral valve endocardiosis. Group I (n = 20) received “Avecarditis®” at a dose of 0.25 mg/kg twice daily 7 days before surgery and for 7 days after, group II (n = 20) served as a control without preoperative drug support.

Regional blockade with bupivacaine was used for anesthesia. Monitoring included electrocardiography, pulse oximetry, noninvasive blood pressure measurement, and recording of readings every 5 minutes.

The results of the study showed that the preoperative use of pimobendan-based drugs significantly reduces hemodynamic complications and ensures a more stable course of anesthesia. The dogs of group I demonstrated better hemodynamic stability with a lower degree of reduction in blood pressure (14.2% in group I versus 31.8% in group II). No complications related to the cardiotoxicity of local anesthetics have been reported.

The developed anesthetic protocol can be recommended for use in dental operations in dogs with mitral valve endocardiosis. 

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