The influence of ultra-fine metal isotopes on the physiological and biochemical parameters of broiler chickens
https://doi.org/10.32634/0869-8155-2026-404-03-42-49
Abstract
The study examined the growth and development indicators of broiler chickens, the digestibility of feed components, the morpho-biochemical parameters of the blood, and the metabolism of elements in the body under the influence of UFC isotopes. The control group received OR, group I — OR + UFC Fe isotope (17 mg/kg of feed), group II — OR + UFC Cu isotope (1.7 mg/kg of feed). A change in the dynamics of live weight gain was noted compared to the control, most pronounced in the first experimental group (by 2.1–6.0%). Digestibility of organic matter and crude fat was higher than the control in the first and second experimental groups, digestibility of crude protein was higher than the control by 9.55–16.7% in all experimental groups.
In the blood of birds from experimental groups I and II, an increase in the number of lymphocytes was observed, in group I — an increase in hemoglobin and its decrease in group II. Biochemical parameters of the bird’s blood serum (AST, creatinine, total bilirubin) indicate an increase in metabolic processes in groups I and II. In groups I and II, a tendency towards a decrease in the content of toxic elements in the bird’s body and an increase in essential elements was noted. In group III, the content of Zn, Cr, Al and Ni in the bird’s body increased. In experimental group I, a decrease in endogenous losses of Fe and Cu was observed. For experimental group II, an increase in endogenous losses was characteristic compared to the control.
Keywords
Supporting agencies: The research was carried out at the expense of the grant of the Russian Science Foundation №. № 25-16-00111
About the Authors
O. V. Kvan
Federal Scientific Center of Biological Systems and
Agrotechnologies of the Russian Academy of Sciences; Orenburg State University
Russian Federation
Russian Federation
Olga Vilorievna Kvan, Doctor of Biological Sciences
29 January 9th st., Orenburg, 460000
13 Pobedy Ave., Orenburg, 460018
V. V. Grechkina
Federal Scientific Center of Biological Systems and
Agrotechnologies of the Russian Academy of Sciences; Orenburg State Agrarian University
Russian Federation
Russian Federation
Viktoriya Vladimirovna Grechkina, Candidate of Biological Sciences
29 January 9th st., Orenburg, 460000
18 Chelyuskintsev st., Orenburg, 460014
E. V. Sheida
Federal Scientific Center of Biological Systems and
Agrotechnologies of the Russian Academy of Sciences; Orenburg State University
Russian Federation
Russian Federation
Elena Vladimirovna Sheida, Doctor of Biological Sciences
29 January 9th st., Orenburg, 460000
13 Pobedy Ave., Orenburg, 460018
I. A. Vershinina
Federal Scientific Center of Biological Systems and
Agrotechnologies of the Russian Academy of Sciences
Russian Federation
Russian Federation
Irina Aleksandrovna Vershinina, Candidate of Biological Sciences
29 January 9th st., Orenburg, 460000
References
1. Kvan O.V. Endogenous losses of substances: optimization of micronutrient supply of farm animal diets (review). Animal Husbandry and Fodder Production. 2023; 106(4): 148‒163 (in Russian). https://doi.org/10.33284/2658-3135-106-4-148
2. Gadde U., Kim W.H., Oh S.T., Lillehoj H.S. Alternatives to antibiotics for maximizing growth performance and feed efficiency in poultry: a review. Animal Health Research Reviews. 2017; 18(1): 26‒45. https://doi.org/10.1017/S1466252316000207
3. Singh V.V, Singh V.K, Tewari D., Gautam S., Singh V.B, Singh P. Performance of Broiler Chicken Fed Diets Supplemented with a Phytogenic Mixture. Indian Journal of Animal Nutrition. 2019; 36(1): 58‒64. https://doi.org/10.5958/2231-6744.2019.00010.0
4. Jiao L. et al. Preparation, characterization, antimicrobial and cytotoxicity studies of copper/zinc- loaded montmorillonite. Journal of Animal Science and Biotechnology. 2017; 8: 27. https://doi.org/10.1186/s40104-017-0156-6
5. Liu S.Y., Macelline S.P., Chrystal P.V., Selle P.H. Progress towards reduced-crude protein diets for broiler chickens and sustainable chicken-meat production. Journal of Animal Science and
6. Biotechnology. 2021; 12: 20. https://doi.org/10.1186/s40104-021-00550-w
7. Yadav S., Jha R. Strategies to modulate the intestinal microbiota and their effects on nutrient utilization, performance, and health of poultry. Journal of Animal Science and Biotechnology. 2019; 10: 2. https://doi.org/10.1186/s40104-018-0310-9
8. Espinosa C.D., Stein H.H. Digestibility and metabolism of copper in diets for pigs and influence of dietary copper on growth performance, intestinal health, and overall immune status: a review. Journal of Animal Science and Biotechnology. 2021; 12: 13. https://doi.org/10.1186/s40104-020-00533-3
9. Byrne L., Murphy R.A. Relative Bioavailability of Trace Minerals in Production Animal Nutrition: A Review. Animals. 2022; 12(15): 1981. https://doi.org/10.3390/ani12151981
10. Sai Kumar B.A.A. Hormonal Regulation of Metabolism, Water, and Minerals. Das P.K., Sejian V., Mukherjee J., Banerjee D. (eds.). Textbook of Veterinary Physiology. Singapore: Springer. 2023; 391–415. https://doi.org/10.1007/978-981-19-9410-4_16
11. Kvan O.V., Sizova E.A., Vershinina I.A., Kamirova A.M. Study of the effect of ultrafine particles of copper and iron on mineral metabolism in the body of broiler chickens on a semisynthetic diet. Agrarian science. 2022; (6): 48–51 (in Russian). https://doi.org/10.32634/0869-8155-2022-360-6-48-51
12. Sizova E.A., Miroshnikov S.A., Lebedev S.V., Levakhin Yu.I., Babicheva I.A., Kosilov V.I. Comparative tests of various sources of microelements in feeding chicken-broilers. Agricultural Вiology. 2018; 53(2): 393–403. https://doi.org/10.15389/agrobiology.2018.2.393eng
13. Scherzad A., Meyer T., Kleinsasser N., Hackenberg S. Molecular Mechanisms of Zinc Oxide Nanoparticle-Induced Genotoxicity. Materials. 2017; 10(12): 1427. https://doi.org/10.3390/ma10121427
14. Garipova N.V., Ryazanov V.A. Ultrafine iron particles in animal husbandry (a review). Trace elements in medicine. 2022; 23(4): 3–13 (in Russian). https://doi.org/10.19112/2413-6174-2022-23-4-3-13
15. Miroshnikov S.A., Garipova N.V., Kholodilina T.N., Kurilkina M.Ya., Duskaev G.K. Productive action and digestibility of feeds after using iron microparticles for feeding of poultry. Animal Husbandry and Fodder Production. 2018; 101(2): 7–16 (in Russian).EDN XZCKLZ
16. Adegbeye M.J. et al. Nanoparticles in Equine Nutrition: Mechanism of Action and Application as Feed Additives. Journal of Equine Veterinary Science. 2019; 78: 29–37. https://doi.org/10.1016/j.jevs.2019.04.001
17. Fan X., et al. Biocatalytic nanomaterials: a new pathway for bacterial disinfection. Adv Mater. 2021;33(33):e2100637. https://doi.org/10.1002/adma.202100637
18. Fisinin V.I., Miroshnikov S.A., Sizova E.A., Ushakov A.S., Miroshnikova E.P. Metal particles as trace-element sources: current state and future prospects. World’s Poultry Science Journal. 2018; 74(3): 523–540. https://doi.org/10.1017/S0043933918000491
19. Sizova E.A. Effect of copper nanoparticles introduced to the diet on cadmium level of broiler chickens. Herald of beef cattle breeding. 2017; (1): 13–20 (in Russian).EDN YHPSKZ
20. Lebedev S. et al. Use of chromium nanoparticles as a protector of digestive enzymes and biochemical parameters for various sources of fat in the diet of calves. AIMS Agriculture and Food. 2021; 6(1): 14–31. https://doi.org/10.3934/agrfood.2021002
21. Xiao M. et al. Taurine regulates mucosal barrier function to alleviate lipopolysaccharide-induced duodenal inflammation in chicken. Amino Acids. 2018; 50(11): 1637–1646. https://doi.org/10.1007/s00726-018-2631-6
22. Grechkina V.V., Kvan O.V., Sheyda Ye.V., Bykov A.V. Experimental assessment of the biotoxicity of Cu-63 and Fe-56 isotopes in relation to modeled microflora. Actual problems of applied biotechnology and engineering. Collection of materials of the International scientific and practical conference. Orenburg: Orenburg State University. 2025; 174–181 (in Russian).EDN MPETUC
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For citations:
Kvan O.V., Grechkina V.V., Sheida E.V., Vershinina I.A. The influence of ultra-fine metal isotopes on the physiological and biochemical parameters of broiler chickens. Agrarian science. 2026;(3):42-49. (In Russ.) https://doi.org/10.32634/0869-8155-2026-404-03-42-49
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