The scaling and optimization technological processes of cultivation of swine erysipelas bacteria

Abstract

The increased needs in the practice of the active antigen identified the economic importance and urgency of the problem of scaling serial production standard by the activity of the antigen of the bacteria of swine erysipelas. In solution these problems the research was conducted on improvement the means and methods of stationary and periodic cultivation the microorganism. The presented data on the needs of Erysipelotnrix rhusiopathiae Hottinger's broth containing more than 150 mg% of amine nitrogen and the polypeptide fraction of Mm 10,000 D and introduction into the nutrient medium organic form of ferrous iron stimulating growth and the level of accumulation of microorganisms fixed and periodic cultivation ability. It proved the feasibility and effectiveness of scaling conditions and technological processes of breeding bacteria swine erysipelas stationary and periodic processes using statistical methods for monitoring indicators in accordance with the requirements of national and international standards.