Quantitative analysis by Raman spectroscopy using potassium hexacyanoferrate (III) as an internal standard
https://doi.org/10.32634/0869-8155-2020-334-1-13-16
Abstract
In this article we proposed a method for quantitative determination of active substance in pharmaceuticals via Raman scattering using potassium ferricyanide as internal standard. We approved this method in ketoprophenum quantitative determination in drug for veterinary use “Ketojekt”. The calculation of metrological requirements of procedures are established proposed method of calibration. Either we demonstrated the focalisation factor of laser beam affects on the method reproducibility. The method provides a precise, rapid, convenient to quantitative analysis that is more effective than the standard HPLC assay.
About the Authors
A. Y. Khrushchev
The Russian State Center for Animal Feed and Drug Standardization and Quality
Russian Federation
123022, Moscow
Russian Federation
123022, Moscow
E. R. Akmaev
The Russian State Center for Animal Feed and Drug Standardization and Quality
Russian Federation
123022, Moscow
Russian Federation
123022, Moscow
V. O. Bondarenko
The Russian State Center for Animal Feed and Drug Standardization and Quality
Russian Federation
123022, Moscow
Russian Federation
123022, Moscow
A. E. Metlin
The Russian State Center for Animal Feed and Drug Standardization and Quality
Russian Federation
123022, Moscow
Russian Federation
123022, Moscow
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Review
For citations:
Khrushchev A.Y., Akmaev E.R., Bondarenko V.O., Metlin A.E. Quantitative analysis by Raman spectroscopy using potassium hexacyanoferrate (III) as an internal standard. Agrarian science. 2020;(1):13-16. (In Russ.) https://doi.org/10.32634/0869-8155-2020-334-1-13-16
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