Immunotropic effect of feed additives based on metaprobiotics and phytobiotics in providing specific immunity in broiler chickens

Relevance. The use of biologically active feed additives that support the development of normal intestinal microflora and aimed at stimulating the body’s defenses is considered by modern immunology as one of the most promising approaches to solving the problem of resisting infectious processes. Therefore, research on replacing antibiotics with drugs that are safe for humans and animals, and the introduction of technologies for the production of environmentally friendly products are a priority. One of the alternative solutions to this problem may be the use of metaprobiotics and phytobiotics.
Methods. 3 groups of broiler chickens were formed: the first — OR + “Probiotsid©-Fito” (“Biotrof” LLC, Russia) at a dosage of 1 kg per 1 ton of feed, the second — OR+ “Probiotsid©-Ultra” (LLC “Biotrof”, Russia) at a dosage of 1 kg per 1 ton of feed, the third is control. Maternal and post-vaccination humoral immunity to IBD, IBD and NB were assessed using test systems ID Screen® IBD Indirect, ID Screen® Infectious Bronchitis Indirect 2.0 (“ID.vet”, France), provided by “Vet Faktor” LLC and a kit for detecting antibodies to NB virus in the hemagglutination inhibition reaction (HI) (FSBI “ARRIAH”, Russia). During the experiment, live weight, the amount of feed consumed were taken into account daily, and production indicators (feed conversion and European productivity index) were calculated according to the Ross 308 broiler breeding guide.
Results. In our study, both drugs had a positive effect on the immunity and zootechnical parameters of broiler chickens. When these drugs are introduced into the diet, the live weight of broiler chickens, the average daily increase in live weight, the safety of livestock increases and the feed conversion decreases. Based on the results of a serological study, the immunotropic effect of drugs based on metaprobiotics and phytobiotics was revealed.

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