The influence of chelated iron-containing complex on the quality of fermented milk products
https://doi.org/10.32634/0869-8155-2025-393-04-159-166
Abstract
The aim of the work is to study the effect of an iron-containing chelate complex (iron ascorbate) on the physico-chemical, organoleptic and microbiological parameters of a fermented milk product. Iron ascorbate tonicotinate was synthesized by a mechanochemical method. The following reagents were used to obtain the complex: ascorbic acid, nicotinic acid, iron (II) sulfate, barium hydroxide 8-aqueous. As a result of studying the physicochemical characteristics, it was found that the introduction of iron ascorbate tonicotinate with different concentrations into the fermented milk product does not significantly affect such parameters as active acidity of the medium, titratable acidity and viscosity. The effect of the concentration of the iron-containing complex on the organoleptic properties of yogurt was studied. It has been established that the taste and smell of the fermented milk product with the addition of iron ascorbate nicotinate do not change compared to the control sample, except for samples with the addition of a chelate complex containing 70% and 100% of the daily iron intake. Fermented milk products enriched with chelate complexes containing 10%, 30% and 50% of the daily iron intake have the best characteristics. It has been established that the color of the resulting drinks changes from milky white, typical of a regular fermented milk product (with the addition of 10 and 30% of the daily iron intake) to a pinkish tint (with the addition of 50%, 70% and 100% of the daily iron intake), which is associated with the color of the chelated iron itself. The paper considers the possibility of enriching a fermented milk product with iron ascorbate nicotinate, which has a positive effect on its quality and properties. The effect of iron ascorbate tonicotinate on the growth and development of Lactobacillus delbrueckii subsp. bulgaricus bacteria was studied. It was found that the chelated form of iron has a stimulating effect on the growth and development of Streptococcus thermophillus and Lactobacillus delbrueckii subsp. Bulgaricus bacteria in concentrations of 1.8 mg/l, 5.4 mg/l and 9 mg/l.
About the Authors
A. V. BlinovRussian Federation
Andrey Vladimirovich Blinov, PhD, Associate Professor, Department of Functional Materials and Engineering Design
Pushkin Str., Stavropol, 355002
A. V. Samovolov
Russian Federation
Artyom Vladimirovich Samovolov, Assistant at the Department of Oil Refining Technology and Industrial Ecology
Pushkin Str., Stavropol, 355002
A. S. Askerova
Russian Federation
Alina Salmanovna Askerova, Laboratory Assistant at the Department of Functional Materials and Engineering Design
Pushkin Str., Stavropol, 355002
A. A. Nagdalyan
Russian Federation
Andrey Ashotovich Nagdalyan, Senior Researcher at the Institute of Food and Industrial Biotechnology
Pushkin Str., Stavropol, 355002
A. M. Serov
Russian Federation
Alexander Mikhailovich Serov, Laboratory Assistant at the Department of Functional Materials and Engineering Design
Pushkin Str., Stavropol, 355002
M. B. Rebezov
Russian Federation
Maksim Borisovich Rebezov, Doctor of Agricultural Sciences, Candidate of Veterinary Sciences, Professor, Chief Researcher; Doctor of Agricultural Sciences, Candidate of Veterinary Sciences, Professor of the Department of Biotechnology and Food Products
26 Talalikhin Str., Moscow, 109316
42 Karl Liebknecht Str., Yekaterinburg, 620075
References
1. Skalnaya M.G., Skalny A.V. Trace elements: the biological role and significance for medical practice. Communication 2. Iron. Problems of biological, medical and pharmaceutical chemistry. 2015; (2): 19-27 (in Russian). https://elibrary.ru/ttgqxv
2. Korobko I.Yu., Zhurnya А.А., Melnikova O.P, Pavlova O.S. Microelements and macroelements and cardiovascular disease. Cardiology in Belarus. 2018; 10(2): 280-289 (in Russian). https://elibrary.ru/lblfmt
3. Kulchavenya E.V. Minerals contributing to human health and well-being. Clinical review for general practice. 2021; 2(1): 58-64 (in Russian). https://doi.org/10.47407/kr2021.2A00033
4. Trukhan D.I., Druk I.V., Viktorova I.A. Not iodine alone. Role of selenium, zinc, vitamins A, C, E in the physiology and pathology of the thyroid gland. Clinical review for general practice. 2024; 5(4): 34-45 (in Russian). https://doi.org/10.47407/kr2024.5A00417
5. Narayanan L. et al. Nutritional and therapeutic potential of bioactive compounds from melons: a mini review. Journal of microbiology, biotechnology and food sciences. 2024; 14(3): e11877. https://doi.org/10.55251/jmbfs.11877
6. Dolgaya M.N. Influence of microelement composition on physiology status in the conditions of rats’ organism. The Animal Biology. 2011; 13(1-2): 98-102 (in Ukrainian). https://elibrary.ru/rkuvsn
7. Filimonov R.M., Fesyun A.D., Filimonova T.R., Borisevich O.O. Role of microelements in drinking mineral waters in metabolic processes of the gastrointestinal tract. Experimental and Clinical Gastroenterology. 2022; (8): 179-189 (in Russian). https://doi.org/10.31146/1682-8658-ecg-204-8-179-189
8. Atakhodjaeva I., Akramova R., Choriyev A., Toxtayev S. S., Li V. Study of a protein-containing and keto-dietary product based on local raw materials. E3S Web of Conferences. 2023; 401: 03037. https://doi.org/10.1051/e3sconf/202340103037
9. Artemieva I., Litvinova E., Andrianova E. Actual aspects of the use of metalloproteinas in the meat industry for effective resource conservation. 19th International Multidisciplinary Scientific GeoConference SGEM 2019. Conference proceedings. SGEM. 2019; 19: 507-514. https://www.elibrary.ru/sagwih
10. Tangatarova S.B., Zhumaeva A.T., Abdullaeva Zh.D. Biological importance of microelements in the human body. Bulletin of Science and Practice. 2024; 10(7): 65-69 (in Russian). https://doi.org/10.33619/2414-2948/104/08
11. Spivak N.Ya., Kaplunenko V.G., Kosinov M.V, Skalny A.V. Antiviral, antioxidant and catalytic activity of trace elements in a low degree of oxidation. Trace elements in medicine. 2020; 21(3): 3-23 (in Russian). https://doi.org/10.19112/2413-6174-2020-21-3-3-23
12. Renata R.B.N., Arely G.R.A., Gabriela L.M.A., Esther M.L.M. Immunomodulatory Role of Microelements in COVID-19 Outcome: a Relationship with Nutritional Status. Biological Trace Element Research. 2023; 201(4): 1596-1614. https://doi.org/10.1007/s12011-022-03290-8
13. Muzakaeva Kh.S., Duskaev M.Z. Metabolic role of manganese in the body. VestnikMeditsinskogo instituta. 2024; (1): 55-60 (in Russian). https://www.elibrary.ru/xxqsxa
14. Blinov A.V., Rekhman Z.A., Golik A.B., Gvozdenko A.A., Nagdalyan A.A., Rebezov M.B. An innovative form of the essential trace element copper for fortification of dairy products. Agrarian science. 2024; (4): 153-159 (in Russian). https://doi.org/10.32634/0869-8155-2024-381-4-153-159
15. Blinov A.V., Rekhman Z.A., Gvozdenko A.A., Golik A.B., Nagdatyan A.A., Rebezov M.B. Dairy product enriched with triple manganese complex. Agrarian science. 2024; (5): 117-123 (in Russian). https://doi.org/10.32634/0869-8155-2024-382-5-117-123
16. Serikova A.S., Asenova B.K., Smolnikova F.Kh., Konganbaev E.K., Rebezov M.B. Study on the mineral composition of grits. International scientific and practical conference dedicated to the memory of V. M. Gorbatov. Moscow: V.M. Gorbatov Federal Scientific Center for Food Systems. 2015; 416-419 (in Russian). https://elibrary.ru/vbdmcf
17. Tangatarova S.B., Khan A.M.A., Zhumaeva A.T. Importance of chemical elements in the human body. Journal of Osh State University Medicine. 2023; (2): 54-59. https://doi.org/10.52754/16948831_2023_2(2)_7
18. Shchetinina S.Yu. The importance of mineral substances for human health. International journal of humanities and natural sciences. 2024; (4-4): 27-31 (in Russian). https://doi.org/10.24412/2500-1000-2024-4-4-27-31
19. Kulibaba S.V., Dolgaya M.N., Ionov I.A. Effect of feeding chelate complexes of trace elements on the average daily balance of Cu, Zn and Mn in the organism of cows during the period of lactation. Scientific Messenger of Lviv National University of Veterinary Medicine and Biotechnologies. 2017; 19(79): 58-61 (in Ukrainian). https://doi.org/10.15421/nvlvet7912
20. Cadet E., Gadenne M., Capront D., Rochette J. Advances in iron metabolism: a transition state. La Revue de Medecine Interne. 2005; 26(4): 315-324 (in French). https://doi.org/10.1016/j.revmed.2004.09.024
21. Ostapenko V.A. Iron and its role in the human body. Fundamental and applied research in conditions of geopolitical instability Materials of theXXIII All-Russian Scientific and Practical Conference. Rostov-on-Don: Manuskript. 2023; 180-184 (in Russian). https://elibrary.ru/mjzmrp
22. Sant-Rayn P, Tye-Din J., Muckenthaler M.U., Swinkels D.W. Iron deficiency. The Lancet. 2021; 397(10270): 233-248. https://doi.org/10.1016/S0140-6736(20)32594-0
23. Dobrokhotova Yu.E., Kerchelaeva S.B. Use of iron drugs for the treatment of iron deficiency anemia in patients in the postpartum period. Lechebnoye delo. 2022; (2): 38-43 (in Russian). https://doi.org/10.24412/2071-5315-2022-12804
24. Polyakova O.A., Klepikova M.V., Litvinova S.N., Isaakyan Yu.A., Ostroumova O.D. Iron deficiency and iron deficiency anemia in general medical practice. The Russian Journal of Preventive Medicine. 2022; 25(12): 127-134 (in Russian). https://doi.org/10.17116/profmed202225121127
25. Simion A.Yu., Ovsyannikov E.S. The impact of iron deficiency anemia on the quality of life of patients with coronary heart disease. The Russian Journal of Preventive Medicine. 2023; 26(5-2): 9 (in Russian). https://elibrary.ru/qshkqd
26. Bogdanov A.N., Voloshin S.V., Tyrenko V.V., Polyakov A.S. Iron deficiency anemia in elderly and senile patients. Advances in gerontology. 2020; 33(6): 1150-1157 (in Russian). https://doi.org/10.34922/AE.2020.33.6.018
27. Zyryanov S.K., Baybulatova E.A. Selection of parenteral iron supplement for iron deficiency anemia: A review. Therapeutic archive. 2024; 96(4): 407-418 (in Russian). https://doi.org/10.26442/00403660.2024.04.202693
28. Martynov A.I. et al. Modern view on treatment of iron and folic acid deficiency. The Russian Journal of Preventive Medicine. 2023; 26(7): 80-87 (in Russian). https://doi.org/10.17116/profmed20232607180
29. Kolosova N.G., Bayandina G.N., Mashukova N.G., Geppe N.A. Iron exchange in the body and ways of correction of its abnormalities. Difficult patient. 2011; 9(8-9): 54-58 (in Russian). https://elibrary.ru/oxftmb
30. Mazurenko E.A., Grinchenko V.S., Bakhmet M.P High technologies for enriching the chemical composition of food products with essential components. Science and innovation — modern concepts. Collection of scientific articles based on the results of the International Scientific Forum. Moscow: Infiniti. 2020; 1: 112-117 (in Russian). https://elibrary.ru/tpyach
31. Tretyak L.N., Rebezov M.B., Antipova A.P, Mordvinova A.O. The analysis of consumer preferences in choosing enriched fermented milk product. Regional aspect. International journal of applied and fundamental research. 2015; (12-6): 978-982 (in Russian). https://elibrary.ru/vbunwr
32. Minzanova S.T et al. Complexation of pectin with macro-and microelements. Antianemic activity of Na, Fe and Na, Ca, Fe complexes. Carbohydrate Polymers. 2015; 134: 524-533. https://doi.org/10.1016/j.carbpol.2015.07.034
33. Dubtsov G.G. et al. Bread and bakery products in prevention of iron-deficiency anaemia. Nutrition. 2019; 9(1): 5-10 (in Russian). https://doi.org/10.20953/2224-5448-2019-1-5-10
34. Wu W., Yang Y, Sun N., Bao Z., Lin S. Food protein-derived ironchelating peptides: The binding mode and promotive effects of iron bioavailability. Food Research International. 2020; 131: 108976. https://doi.org/10.1016/j.foodres.2020.108976
35. Blinov A.V., Maglakelidze D.G., Gvozdenko A.A., Golik A.B., Kolodkin M.A., Rekhman Z.A. Functional Milk Drink Enriched with Iron (II) Ascorbate Isoleucinate. Food Industry. 2023; 8(3): 87-96 (in Russian). https://doi.org/10.29141/2500-1922-2023-8-3-9
36. Mikhailina M.A., Shlenkin A.K. Trace elements are essential components of food. In the world of scientific discoveries. Proceedings of the II International student scientific conference. Ulyanovsk: Ulyanovsk State Agrarian University. 2018; 6(2): 149-151 (in Russian). https://elibrary.ru/ynzszn
37. Kodentsova VM., Vrzhesinskaya O.A., Risnik D.V. The analysis of domestic and international policy of food fortification with trace elements and salt iodization. Trace elements in medicine. 2015; 16(4): 3-20 (in Russian). https://elibrary.ru/vsvfgx
38. Logvinchuk T.M. Selection of micronutrients — vitamins and minerals for the development of fortified instant tea drinks. Tendentsii razvitiya naukiiobrazovaniya. 2022; 84(1): 136-138 (in Russian). https://doi.org/10.18411/trnio-04-2022-35
39. Kostenko K.V., Blinov A.V, Poidun F.A., Pirogov M.A., Serov A.M., Rebezov M.B. A functional drink based on reconstituted whey powder and a triple chelate complex of the essential trace element zinc. Agrarian science. 2024; (12): 158-165 (in Russian). https://doi.org/10.32634/0869-8155-2024-389-12-158-165
40. Blinov A.V. et al. Selenium nanoparticles stabilized with chitosan for fortifying dairy products. Agrarian science. 2024; (9): 130-135 (in Russian). https://doi.org/10.32634/0869-8155-2024-386-9-130-135
Review
For citations:
Blinov A.V., Samovolov A.V., Askerova A.S., Nagdalyan A.A., Serov A.M., Rebezov M.B. The influence of chelated iron-containing complex on the quality of fermented milk products. Agrarian science. 2025;1(4):159-166. (In Russ.) https://doi.org/10.32634/0869-8155-2025-393-04-159-166