Anthelmintic drugs are widely used in veterinary practice. This is due to their high economic efficiency and the widespread distribution of bacteria and parasites. The sensitivity and specificity parameters for the determination of anthelmintic substances in raw meat based on immunomicrochip technology have been developed. The use of immunomicrochip technology for monitoring studies can reduce time and costs compared with classical methods of analysis.

Studies of the prevalence of coronavirus infection of cats on the territory of metropolis allow to determine regularities of development of epizootics in metropolis and to assess emerging risks. Multipoint studies of the incidence of cats with coronavirus infection in various administrative districts of Moscow showed an uniformly high prevalence in the range from 50 to 78%, which corresponds to the nature of the free spread of epizootics in the entire metropolis.

The aim of the study was to develop a differential diagnostic nutrient medium for the rapid diagnosis of animal dermatophytosis. Abroad for these purposes environments such as Dermatophyte Test Medium (DTM) are successfully used, but in Russia such diagnostics has not been developed. As a result of the studies, experimental samples of the DTM-Expert nutrient medium were prepared with the optimal composition and ratio of growth and selective supplements. By the growth, indicator and selective properties the obtained diagnostic medium was not inferior to foreign analogues, while it is cheaper and more ergonomic in use. Using the developed DTM-Expert nutrient medium in laboratories will significantly simplify the diagnosis of dermatophytosis and increase its effectiveness.

Relevance Insufficient attention is paid to the practical use of enzyme preparations, although numerous studies have proven the effectiveness of these substances in the feeding of animals and poultry. Establishing the feasibility and effectiveness of the use of the enzyme preparation as part of animal feed for growing broiler chickens is an urgent task. Methods To conduct the experiment using the method of analog groups, 4 groups of broiler chickens (1 control and 3 experimental) of the COBB 500 cross-breed at a daily age of 100 animals (50 heads of males and 50 heads of hens) in each were formed. The experiments were carried out from daily from 35.7 to 36.3 days of age. Results Experimentally studied different doses of the multienzyme enzyme Axtra XAP 101 in the composition of feed and the optimum doses in the amount of 7-9% of the dry matter of feed. Multienzyme enzyme preparation Axtra XAP 101 effect on indices of meat productivity of broiler chickens. It is established that this preparation promotes increase of average daily gain, reduction of conversion of a forage and positively influences their safety.

The successful introduction of genomic selection into production was a decisive technological leap for the effective implementation of breeding programs around the world. The number of registered populations, the optimization of scientific methods, the use of information technologies, as well as the testing of the animal genome at once by a large number of markers make it possible to achieve more significant genetic progress in the breeds; it is not jellied to select animals by traditional methods. Methods The article reflects the results of a genomic evaluation of the breeding value of 14 repair bulls, obtained by targeted custom mating. Results According to the results of the analysis, it was established that the scope of the total genomic assessment of the calves' value of gobies (GTPI) was from 1276 to 2049, and the average goby index was 1566 with 71% accuracy. The highest breeding value index for milk yield was for two bulls (GPTA = +371 and +721) and two for fat content in milk (+0.16 and +0.15). Conducted organizational and research work has allowed to develop a conceptual scheme for the early selection of high-value genotypes with subsequent seed production (12-14 months) as from bulls-improvers.

Relevance Today, the need of the world market for fine-fiber silk threads and high-quality silk products requires the improvement of scientific research in this area, namely, a thorough study of the effects of various environmental factors on the quality and productivity of the silkworm. As you know, these factors include temperature, air humidity, movement and change of air, quantity and quality of feed, exposure to radiant energy, etc. Methods Scientists of the Department of Sericulture and Tuticulture emphasized the study of the influence of the amount of feed and temperature changes on the activity of the silk gland, and therefore, on the technological parameters of cocoons. During the study, we took mulberry silkworm caterpillars of the Ipacchi-1 x Ipacchi-2 hybrid, widely distributed in Uzbekistan, which was created by scientists of the Silk Production Research Institute. Caterpillars were fed with different amounts of food at different air temperatures. Results The results of the study showed that when feeding silkworm caterpillars with different amounts of feed and at different feeding temperatures, the technological indicators of cocoons, namely the output of raw silk, the total and continuous length of the cocoon thread, and reeling are different. In particular, at 100% feeding and optimal feeding temperature, the yield of raw silk increased by 12.2%, unwinding by 12.5-24.0%, the total length of cocoon thread by 41.4-43.2%, continuous unwinding by 43.6-45.8% and fineness of cocoon filament by 42.3-44.2%. When feeding the caterpillars with a sufficient amount of feed, the larvae develop well, the activity of the silk glands improves and a sufficient amount of silk mass accumulates. As a result, a greater amount of silk is curled in the cocoon shell, which helps to increase the technological parameters of the cocoon.

The article presents the results of physiological assessment of the growing fattened young pigs in terms of modeling technological stress. It was found that the use of adaptogens (primarily dihydroquercetin) helps to reduce the negative effects of stress factors on the animal body, including improved digestibility of feed nutrients, metabolism in experimental animals. The experiments were performed at the physiological yard of the Federal Science Center for Animal Husbandry named after Academy Member L.K. Ernst on 36 heads of crossbred pigs (F-2: (BWxL)xD). Groups of animals were formed on the principle of pairs-analogues in the period after reaching a live weight of an average of 35 kg (n = 9) and divided into 4 groups: 1) Base Diet (BD), stress-; 2) BD, stress+; 3) BD, stress+, +organic Se, 20 mg/kg of feed; 4) BD, stress+, +dihydroquercetin, 40 mg/kg of feed. The duration of the experiment was 36 days. The results of studies on the digestibility of nutrients of feed rationation show that the inclusion in the feed for growing young pigs-40 mg dihydroquercetin (adaptogen) per 1 kg of feed contributed to the best use of feed nutrients against the background of simulated technological stress with equality and some increase in individual indicators of digestibility in comparison with control (stress-) - dry matter by 2.9; organic matter by 1.8; crude protein - by 2.6 abs.% (p > 0.05). Compared with the indicators of animals of the 2nd control group, the digestibility of dry and organic matter significantly increased - by 2.2 and 1.8 abs.% (p < 0.05), and with indicators of the 3rd experimental group - dry, organic matter, crude fat and fiber, respectively, 2.4; 2.2; 11.1 and 7.2 abs.% (p < 0.05). The results obtained for the study of blood parameters in animals of experimental groups in comparison with the control, indicate in general the intensive course of anabolic processes in their body, including under the influence of the studied factors, which led to positive changes in some morphological and biochemical parameters of blood in animals (increase in protein index, concentration of magnesium, iron, phospholipids, hemoglobin), from which it can be concluded that the use of a bioflavonoid (dihydroquercetin) improves the adaptation of the body to technological stresses, leveling its negative consequences.

Relevance Despite the available information on the effectiveness of a number of agricultural crops, there remains a discussion of the impact of the main soil treatment methods and the fertilization system in crop rotation on the yield of egg barley in the region. Therefore, the development of the most optimal combination of basic soil and fertilizer treatment for barley will allow to maximize the potential of plants and obtain high yields. Solving this problem remains an important task of farming. Methods In the long stationary field experience laid down at the Belgorodskiy Agrarian Scientific Center in 1987 in the south-western part of the Central Chernozem zone, the effects of the methods of basic soil treatment and various doses of organic and mineral fertilizers on the productivity of egg barley were studied during four rotations of grain-growing crop rotation. Results For an average of four rotations on absolute control variants due to natural soil fertility, barley yields were 2.45 t/ha. Single (NPK) 50 and double doses (NPK) 100 of mineral fertilizers increased yields by 36.7and49.8%, organic - by22.0 and33.5, respectively, and their interactions - by 49.4 and 70.6%. Deep soil treatment methods had little advantage over minimal treatment. In the production process, the share of soil treatment methods is 0.12%, organic fertilizers - 25.6%, and mineral fertilizers - 71.0%.

Relevance One of the most effective means of increasing the yield of buckwheat in the Volga-Vyatka region is the creation of new highly productive, resistant to adverse environmental conditions and valuable quality varieties that meet the requirements of intensive agriculture. Methods One of the most effective means of increasing buckwheat yields in the Volga-Viatsk region is the creation of new high-productivity, resistant to unfavourable environmental conditions and valuable varieties that meet the requirements of intensive farming. In order to realize this goal, research work on buckwheat selection is being carried out in Nizhny Novgorod Research Agricultural Institute - Branch of Federal Agricultural Research Center of the North-East. This article presents the results of studies of promising varieties of buckwheat in the competitive class testing according to the main economic and biological indicators determining the suitability of the variety for use in agricultural production. The studies were carried out in 2016-2018 according to the method of state testing. Result As a result of the examination of nine grade samples in the competitive grade test, samples 45/14-1 and 145/15-1 were isolated for a number of household values. Their harvest averaged 1.80 and 2.03 t/ha, respectively, during the test years, which is 0.11 and 0.34 t/ ha higher than the Arrow standard. Varieties with high productivity elements are identified. It has been found that all samples studied by weight of 1000 grains belong to the group of large-grain varieties.

Modern agriculture sets as its main goal the search and implementation of environmentally friendly technologies for cultivating crops, restoring soil fertility and reducing pesticidal load. One of the main components of this technology is the use of integrated pest management that use both chemical and biological plant protection products. In this regard, the aim of the work was to compare the effectiveness of individual technology elements, namely seed treatment and treatment with plant and chemical fungicides and their combination with the development of diseases, harvest and spring wheat crop. As a result of the studies, it was found that the use of the biofungicide Phytosporin-M, Zh together with chemical fungicides on spring wheat crops contributes to the greatest reduction in the development of root rot, increase in the number of productive plant stems, increases the number of grains in the ear and its weight in comparison with traditional and biologized protection technologies plants. It was found that on average over three years the highest yield of spring wheat of the Ekada 109 variety was obtained using a variant using chemical and biological fungicides (2.33 t/ha) with a profitability level of grain production of 61%.

Relevance One of the main factors negatively affecting agriculture and the environment in Uzbekistan is soil salinization. Methods In this article given the results of field experiments on improving leaching technology in the salty fields of Bukhara oasis with using chemical component Biosolvent. Scientific researches were carried in irrigated fields of scientific-research center of Tashkent institute of irrigation and agricultural mechanization engineers Bukhara Branch (TIIAME BB) which is located in Bukhara region, Kagan district, during 2017-2019 years. Results Leaching saline soils with using Biosolvent reduces salt content in the active soil layer from 0.376% to 0.204, while desalinization ratio will be 1.84. With this technology leaching norm was 30% less compared to the control.

As a rule, it takes on average 25 years to develop new apple cultivars and include them in the State Register of breeding achievements. Usually the same time is spent for the widespread introduction of a new cultivar into production. This does not suit the producers, as during this time, as a rule, the requirements for cultivars change and increase due to changes in the technology of cultivation of apple orchards. Breeders face a difficult task to accelerate the creation of apple cultivars and their rapid introduction into industrial and amateur gardens. The time of single breeders is over, and in order for new cultivars to meet the requirements, they must be with a certain habit, immunity to scab, precocity, regular and high yield; have fruits with a bright color (red, yellow or green) of certain weight and size. Winter cultivars should have durability of fruit, rich taste and high marketability. Only a large interdisciplinary team of researchers can solve the problem with such requirements. Besides breeders, these groups also should include gardeners, geneticists, cytoembriologists, physiologists, biochemists, phytopathologists and agronomists with the corresponding machinery equipment. Large hybrid funds, giving the opportunity to rigidly reject hybrid seedlings, are needed for constant updating of the assortment. The establishing of small production testing of varieties in the institution-originator already in the transfer of the varieties to the state test can seriously reduce the time of introduction of new varieties into production. Such well-coordinated interdisciplinary teams can create apple cultivars with a whole range of economic and biological characteristics that meet the high requirements of the production.

Relevance The effectiveness of creating integrated structures is estimated by the magnitude of the synergistic effect. Methods The article substantiates the need for its purposeful formation and proposes a methodology for analytical support for the effective integration of agricultural organizations. Results The internal and external sources of the synergistic effect are identified, which form the corresponding integration potentials: production, organizational and personnel, potential for working capital savings, potential for increasing market power, investment, financial, potential for specific assets, market, state support and regulation, replacement of the transaction sector. A system of models is presented that reflects the formation of integration benefits and the classification of the external development potential of integration processes.